摘要:
2-Amino-3,5-di-(halomethyl)-pyrazines of the general formula I ##STR1## where X is either chlorine or bromine, m and n may each be 0, 1, 2 or 3 and R.sup.1 and R.sup.2 are each hydrogen or a protective group or may furthermore be bonded to one another, in particular those compounds of the formula I in which m is 1 and n is 2 and/or R.sup.1 and R.sup.2 together form a phthaloyl radical, are useful intermediates for the pteridine building block of folic acid or folic acid analogs.They are obtained by a method in which a 2-amino-3,5-dimethylpyrazine of the general formula II ##STR2## is treated with a chlorinating or brominating agent and, where R.sup.1 and/or R.sup.2 are protective groups, these are, if desired, eliminated when the chlorination or bromination is complete.
摘要:
2-Amino-3-cyano-5-dialkoxymethylpyrazine derivatives of the general formula III ##STR1## where R.sup.1 and R.sup.2 are each hydrogen or a protective group usually employed for amino groups and R.sup.5 and R.sup.6 are each alkyl of 1 to 4 carbon atoms, or together form an ethylene or propylene radical which is unsubstituted or substituted by methyl, are prepared starting from a novel 3-halomethyl-5-dihalomethyl-2-aminopyrazine derivative of the formula IV ##STR2## where X is Cl or Br, via a novel intermediate of the general formula I ##STR3## where R.sup.3 is --CH.sub.2 --O--CO--CH.sub.3 (a), --CH.sub.2 OH (b), ##STR4## or --C.tbd.N (d) and R.sup.4 is --CHCl.sub.2 or --CHBr.sub.2 or, where R.sup.1 and R.sup.2 are each a protective group, R.sup.4 may furthermore be ##STR5##The compounds according to the invention are useful intermediates for the preparation of folic acid and active compounds derived from this.
摘要:
.alpha.-(o-Chlorophenyl)-aminomethylene-.beta.-formylaminopropionitrile, process for its preparation by reacting a metal salt of .alpha.-formyl-.beta.-formylaminopropionitrile with a salt of o-chloroaniline in an aqueous medium, and use of the product to prepare the compound of the formula ##STR1## by reaction with acetamidine. The pyrimidine thus obtained is an intermediate for the preparation of vitamin B.sub.1.
摘要:
An improved method of manufacture of 2-methyl-4-amino-5-formylaminomethylpyrimidine (II), wherein a N-substituted or unsubstituted .alpha.-aminomethylene-.beta.-formylaminopropionitrile (I) is reacted with acetamidine.Compound II is an intermediate for the manufacture of vitamin B.sub.1.
摘要:
The invention relates to a pumped storage power plant (1) comprising at least one lower storage space (11) that is arranged underground and at least one upper storage space (12) that is separate from the lower storage space and arranged above ground or underground, wherein the lower storage space (11) is arranged in a greater depth than the upper storage space (12), and comprising at least one liquid line (15, 16) that is/are guided within the upper storage space (12) and within the lower storage space (11) respectively and that is/are connected to at least one hydraulic force and/or work machine (26, 27) of the pumped storage plant or can be connected via switchable valves (28, 29), and comprising at least one pressurized gas line (17, 18) that is/are guided within the upper storage space (12) and within the lower storage space (11) respectively and that is/are connected to a pressurized gas force and/or work machine (21, 22) of the pumped storage power plant or can be connected via switchable valves (24, 25), wherein the pumped storage power plant is configured for transporting a liquid medium (5, 7) from the upper storage space (12) into the lower storage space (11) and vice versa through the liquid lines (15, 16) and the hydraulic force and/or work machine (26, 27), and the pressurized gas force and/or working machine (21, 22) is configured for optionally producing a pressurized gas pressure of a pressurized gas (4, 6) at least in the lower storage space (11), which gas pressure can differ from a gas pressure in the upper storage space (12). Furthermore, the invention relates to a power plant and to methods for energy storage.
摘要:
The invention relates to a pumped storage power plant (1) comprising at least one lower storage space (11) that is arranged underground and at least one upper storage space (12) that is separate from the lower storage space and arranged above ground or underground, wherein the lower storage space (11) is arranged in a greater depth than the upper storage space (12), and comprising at least one liquid line (15, 16) that is/are guided within the upper storage space (12) and within the lower storage space (11) respectively and that is/are connected to at least one hydraulic force and/or work machine (26, 27) of the pumped storage plant or can be connected via switchable valves (28, 29), and comprising at least one pressurized gas line (17, 18) that is/are guided within the upper storage space (12) and within the lower storage space (11) respectively and that is/are connected to a pressurized gas force and/or work machine (21, 22) of the pumped storage power plant or can be connected via switchable valves (24, 25), wherein the pumped storage power plant is configured for transporting a liquid medium (5, 7) from the upper storage space (12) into the lower storage space (11) and vice versa through the liquid lines (15, 16) and the hydraulic force and/or work machine (26, 27), and the pressurized gas force and/or working machine (21, 22) is configured for optionally producing a pressurized gas pressure of a pressurized gas (4, 6) at least in the lower storage space (11), which gas pressure can differ from a gas pressure in the upper storage space (12). Furthermore, the invention relates to a power plant and to methods for energy storage.
摘要:
A device for fine honing cylindrical surfaces, such as the bearings of a crankshaft, in which the surface is stationarily supported while an annular tool holder separable along a diameter is disposed around the surface. The tool holder has housing elements therein and is rotated about the axis of the surface while being oscillated in a direction parallel to the axis. The tool holder is rotatable in a housing which is also separable along a diameter of the tool holder while the housing is supported for adjustable positioning to align the tool holder with the surface.
摘要:
Heavy crude oil is recovered from a subterranean formation by a process comprising(a) heating said formation, and(b) subsequently flooding the formation with a cold aqueous solution containing a polymer additive which increases its viscosity.