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公开(公告)号：US08481963B2
公开(公告)日：2013-07-09
申请号：US13406157
申请日：2012-02-27
IPC分类号： H01J37/147 , H01J37/04 , G21K1/04 , H01J49/06
CPC分类号： H01J37/045 , G21K1/04 , H01J37/147 , H01J49/067
摘要： Described herein is an ion slicer that: a) accelerates an ion beam towards a first electrode comprising an ion entrance slit, where the first electrode blocks a portion of ions with high displacement from the axis of the ion beam, thereby slicing the ion beam; and then b) decelerates the ion beam after it is sliced.
摘要翻译： 本文描述的是一种离子切片机，其特征在于：a）将离子束加速至包括离子入口狭缝的第一电极，其中第一电极阻挡离子束轴线高位移的一部分离子，从而切割离子束; 然后b）在离子束切片后减速。
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公开(公告)号：US20120217388A1
公开(公告)日：2012-08-30
申请号：US13406182
申请日：2012-02-27
CPC分类号： H01J37/045 , G21K1/04 , H01J37/147 , H01J49/067
摘要： Provided herein is a bladed ion slicer for blocking ions in an ion beam that have significant distance from the beam axis. In certain embodiments, the bladed ion slicer comprises a body; a first elongated blade; and a second elongated blade; wherein the ion slicer comprises a slit that extends through the body through which ions pass and wherein the edges of the first and second elongated blades define the entrance of the slit and are pointing towards the ion beam. A mass spectrometer system and method for removing unwanted ions are also provided.
摘要翻译： 本文提供了一种叶片式离子限制器，用于阻挡离子束离子的距离远离束轴。 在某些实施例中，叶片离子限制器包括主体; 第一细长刀片; 和第二细长叶片; 其中所述离子限定器包括延伸穿过所述主体的狭缝，离子通过所述狭缝，并且所述第一和第二细长叶片的边缘限定所述狭缝的入口并指向所述离子束。 还提供了用于去除不想要的离子的质谱仪系统和方法。
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公开(公告)号：US20120217387A1
公开(公告)日：2012-08-30
申请号：US13406157
申请日：2012-02-27
CPC分类号： H01J37/045 , G21K1/04 , H01J37/147 , H01J49/067
摘要： Described herein is an ion slicer that: a) accelerates an ion beam towards a first electrode comprising an ion entrance slit, where the first electrode blocks a portion of ions with high displacement from the axis of the ion beam, thereby slicing the ion beam; and then b) decelerates the ion beam after it is sliced.
摘要翻译： 本文描述的是一种离子切片机，其特征在于：a）将离子束加速至包括离子入口狭缝的第一电极，其中第一电极阻挡离子束轴线高位移的一部分离子，从而切割离子束; 然后b）在离子束切片后减速。
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公开(公告)号：US5777325A
公开(公告)日：1998-07-07
申请号：US643708
申请日：1996-05-06
申请人： Scot R. Weinberger , Edward P. Donlon , Yevgeny Kaplun , Tor C. Anderson , Liang Li , Larry Russon , Randy Whittal
发明人： Scot R. Weinberger , Edward P. Donlon , Yevgeny Kaplun , Tor C. Anderson , Liang Li , Larry Russon , Randy Whittal
CPC分类号： H01J49/40 , H01J49/025
摘要： A laser desorption ionization instrument for and method of measuring the molecular weight of large organic molecules includes a time of flight mass spectrometer (TOF MS). The TOF MS instrument provides optimized optic design for both DC and TLF modes. The invention further provides dynamic resolution enhancement for a given ejection pulse, along with optimized ion ejection pulses relative to the ion optic elements. The invention also provides means for compensating for difference in total kinetic energy among ions of different mass; high resolution detection means for improved sensitivity for large molecular weight species. The invention further provides x-y-z stage for sample presentation of both standard MALDI and gel or membrane based samples.
摘要翻译： 用于测量大型有机分子分子量的激光解吸电离仪及其测定方法包括飞行时间质谱仪（TOF MS）。 TOF MS仪器为DC和TLF模式提供优化的光学设计。 本发明还提供了对于给定的喷射脉冲的动态分辨率增强以及相对于离子光学元件的优化的离子喷射脉冲。 本发明还提供了补偿不同质量离子之间总动能差异的方法; 高分辨率检测手段，用于提高大分子量物种的灵敏度。 本发明还提供用于标准MALDI和基于凝胶或膜的样品的样品呈现的x-y-z级。
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