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公开(公告)号：US06348175B1
公开(公告)日：2002-02-19
申请号：US09412483
申请日：1999-10-05
IPC分类号： A61M114
CPC分类号： B01F7/00758 , A61M1/1698 , A61M1/262 , A61M2206/14 , B01D63/02 , B01D63/043 , B01D63/16 , B01D65/08 , B01D2313/20 , B01D2321/2041 , B01D2321/2083 , Y10S261/28
摘要： A blood membrane oxygenator having a housing defining a blood flow path, a rotor hub in the form of a double lumen shaft, and a plurality of distributor disks each having a plurality of hollow fibers which extend across the housing blood flow path. The plurality of distributor disks rotate within the housing to mix the blood resulting in three-dimensional mixing, disruption of the blood boundary layer and efficient blood oxygenation.
摘要翻译： 具有限定血液流动通道的壳体的血液膜氧合器，双腔轴心形式的转子轮毂，以及多个分配器盘，每个分配盘具有跨过壳体血液流路延伸的多个中空纤维。 多个分配器盘在壳体内旋转以混合血液，导致三维混合，血液边界层破裂和有效的血氧合。
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公开(公告)号：US6106776A
公开(公告)日：2000-08-22
申请号：US837048
申请日：1997-04-11
IPC分类号： A61M1/16 , A61M1/22 , A61M1/26 , B01D63/02 , B01D63/04 , B01D63/16 , B01D65/08 , B01F7/00 , A61M1/14
CPC分类号： B01F7/00758 , A61M1/262 , B01D63/02 , B01D63/043 , B01D63/16 , B01D65/08 , A61M1/1698 , A61M2206/14 , B01D2313/20 , B01D2321/2041 , B01D2321/2083 , Y10S261/28
摘要： A blood membrane oxygenator has a housing defining a blood flow path, a rotor hub in the form of a double lumen shaft, and a plurality of distributor disks each having a plurality of hollow fibers which extend across the housing blood flow path. The plurality of distributor disks rotate within the housing to mix the blood resulting in three-dimensional mixing, disruption of the blood boundary layer and efficient blood oxygenation.
摘要翻译： 血液膜氧合器具有限定血流路径的壳体，双腔轴心形式的转子轮毂，以及多个分配盘，每个分配盘具有跨过壳体血液流路延伸的多个中空纤维。 多个分配器盘在壳体内旋转以混合血液，导致三维混合，血液边界层破裂和有效的血氧合。
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3.发明授权Membrane apparatus with enhanced mass transfer, heat transfer and pumping capabilities via active mixing 失效膜装置通过主动混合具有增强的传质，传热和泵送能力公开(公告)号：US06723284B1
公开(公告)日：2004-04-20
申请号：US09707040
申请日：2000-11-06
IPC分类号： A61M114
CPC分类号： B01F7/00758 , A61M1/1006 , A61M1/101 , A61M1/1012 , A61M1/1029 , A61M1/1629 , A61M1/1698 , A61M1/26 , A61M1/262 , A61M1/267 , A61M2206/14 , B01D63/026 , B01D63/043 , B01D63/16 , B01D65/08 , B01D2313/38 , B01D2321/2066 , B01D2321/2083 , Y10S128/03 , Y10S165/357
摘要： A combination mass transfer and pump apparatus, which in a single step actively mixes a first mass and a second mass and simultaneously pumps one of the first mass and the second mass through the apparatus. The combination mass transfer and pump apparatus substantially comprises a housing and at least one distributor element having a plurality of selectively fluid-permeable membrane elements wherein the at least one distributor element is agitated within the second mass such that the first mass diffuses across the selectively fluid-permeable membrane elements, mixing with the second mass, and in the same step the second mass is pumped through the housing.
摘要翻译： 组合质量传递和泵装置，其在单步中主动混合第一质量块和第二质量块，同时通过装置泵送第一质量块和第二质量块中的一种。 组合质量传递和泵装置基本上包括壳体和至少一个具有多个选择性流体可渗透膜元件的分配器元件，其中至少一个分配器元件在第二质量块内被搅动，使得第一质量块扩散穿过选择性流体 不渗透膜元件，与第二质量块混合，并且在相同步骤中，第二质量泵送通过壳体。
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4.发明授权Membrane apparatus with enhanced mass transfer, heat transfer and pumping capabilities via active mixing 失效膜装置通过主动混合具有增强的传质，传热和泵送能力公开(公告)号：US07122151B2
公开(公告)日：2006-10-17
申请号：US10827400
申请日：2004-04-19
CPC分类号： B01F7/00758 , A61M1/1006 , A61M1/101 , A61M1/1012 , A61M1/1029 , A61M1/1629 , A61M1/1698 , A61M1/26 , A61M1/262 , A61M1/267 , A61M2206/14 , B01D63/026 , B01D63/043 , B01D63/16 , B01D65/08 , B01D2313/38 , B01D2321/2066 , B01D2321/2083 , Y10S128/03 , Y10S165/357
摘要： A combination mass transfer and pump apparatus, which in a single step actively mixes a first mass and a second mass and simultaneously pumps one of the first mass and the second mass through the apparatus. The combination mass transfer and pump apparatus substantially comprises a housing and at least one distributor element having a plurality of selectively fluid-permeable membrane elements wherein the at least one distributor element is agitated within the second mass such that the first mass diffuses across the selectively fluid-permeable membrane elements, mixing with the second mass, and in the same step the second mass is pumped through the housing.
摘要翻译： 组合质量传递和泵装置，其在单步中主动混合第一质量块和第二质量块，同时通过装置泵送第一质量块和第二质量块中的一种。 组合质量传递和泵装置基本上包括壳体和至少一个具有多个选择性流体可渗透膜元件的分配器元件，其中至少一个分配器元件在第二质量块内被搅动，使得第一质量块扩散穿过选择性流体 不渗透膜元件，与第二质量块混合，并且在相同步骤中，第二质量泵送通过壳体。
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5.发明授权Membrane apparatus with enhanced mass transfer, heat transfer and pumping capabilities via active mixing 有权膜装置通过主动混合具有增强的传质，传热和泵送能力公开(公告)号：US06217826B1
公开(公告)日：2001-04-17
申请号：US09157815
申请日：1998-09-21
IPC分类号： A61M114
CPC分类号： B01F7/00758 , A61M1/1006 , A61M1/101 , A61M1/1025 , A61M1/1086 , A61M1/1629 , A61M1/1698 , A61M1/26 , A61M1/262 , A61M1/267 , A61M2205/33 , A61M2205/3303 , A61M2206/14 , B01D63/02 , B01D63/026 , B01D63/043 , B01D63/16 , B01D65/08 , B01D2313/243 , B01D2313/38 , B01D2321/2041 , B01D2321/2066 , B01D2321/2083
摘要： A combination mass transfer and pump apparatus, which in a single step actively mixes a first mass and a second mass and simultaneously pumps one of the first mass and the second mass through the apparatus. The combination mass transfer and pump apparatus substantially comprises a housing and at least one distributor element having a plurality of selectively fluid-permeable membrane elements wherein the at least one distributor element is agitated within the second mass such that the first mass diffuses across the selectively fluid-permeable membrane elements, mixing with the second mass, and in the same step the second mass is pumped through the housing.
摘要翻译： 组合质量传递和泵装置，其在单步中主动混合第一质量块和第二质量块，同时通过装置泵送第一质量块和第二质量块中的一种。 组合质量传递和泵装置基本上包括壳体和至少一个具有多个选择性流体可渗透膜元件的分配器元件，其中至少一个分配器元件在第二质量块内被搅动，使得第一质量块扩散穿过选择性流体 不渗透膜元件，与第二质量块混合，并且在相同步骤中，第二质量泵送通过壳体。
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公开(公告)号：US5501663A
公开(公告)日：1996-03-26
申请号：US87487
申请日：1993-07-02
CPC分类号： A61M1/1678 , A61M1/1698 , A61M1/26 , Y10S128/03 , Y10S261/28
摘要： An intravenous fiber membrane oxygenator is disclosed in several embodiments wherein the fibers either run at a transverse angle relative to the longitudinal axis of the oxygenator and/or are of a reduced length to optimize the gas transfer efficiency of the oxygenator. Various helical or spiral wraps of fibers are disclosed. One embodiment utilizes two sets of longitudinally extending fibers wherein the oxygen gas is moved in opposite directions from a central location of the oxygenator.
摘要翻译： 在几个实施方案中公开了静脉内纤维膜氧合器，其中纤维相对于氧合器的纵向轴线以横向角度运行和/或具有减小的长度以优化氧合器的气体转移效率。 公开了各种螺旋或螺旋形的纤维卷。 一个实施例使用两组纵向延伸纤维，其中氧气从氧合器的中心位置沿相反方向移动。
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公开(公告)号：US5537335A
公开(公告)日：1996-07-16
申请号：US554109
申请日：1995-11-06
IPC分类号： A61F2/24 , G05D16/20 , A61B5/0235
CPC分类号： G05D16/2013 , A61F2/2472 , Y10T137/0352
摘要： A fluid delivery apparatus including a chamber for holding a conduit, such as a portion of a human vascular tissue, a fluid supply source for delivering a fluid into the conduit and a fluid pressure modulating device for modulating the fluid pressure supplied from the fluid source before the fluid enters the conduit. The modulating device produces a fluid having a desired pressure waveform for delivery to the conduit. The modulating device includes a microprocessor that digitizes the desired pressure waveform into a plurality of discrete digitized data points and stores a motion controller computer program. The modulating device further includes a motion controller which receives the digitized data points and the motion controller computer program and which at least partially restricts the delivery of the fluid to the conduit based on the digitized data points and the motion controller computer program to produce the desired pressure waveform for delivery to the conduit. An associated method of delivering a fluid having desired pressure to a conduit is also provided.
摘要翻译： 一种流体输送装置，包括用于保持诸如人血管组织的一部分的导管的腔室，用于将流体输送到导管中的流体供应源，以及用于调节从流体源供应的流体压力的流体压力调节装置， 流体进入管道。 调制装置产生具有用于输送到导管的期望压力波形的流体。 调制装置包括微处理器，其将所需压力波形数字化为多个离散数字化数据点并存储运动控制器计算机程序。 调制装置还包括运动控制器，其接收数字化的数据点和运动控制器计算机程序，并且至少部分地基于数字化的数据点和运动控制器计算机程序来限制流体输送到导管，以产生期望的 用于输送到导管的压力波形。 还提供了将具有期望压力的流体输送到导管的相关方法。
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