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公开(公告)号：US5157262A
公开(公告)日：1992-10-20
申请号：US706004
申请日：1991-05-28
申请人： Hermann Marsoner , Herbert Kroneis , Hellfried Karpf , Otto S. Wolfbeis , Helmut List , Alfred Leitner
发明人： Hermann Marsoner , Herbert Kroneis , Hellfried Karpf , Otto S. Wolfbeis , Helmut List , Alfred Leitner
CPC分类号： G01N21/77 , G01N21/255 , G01N2021/174 , G01N2021/7786 , G01N21/6428 , G01N21/81 , G01N2201/0621 , G01N2201/0622
摘要： Due to the size of the devices used for the excitation and measuring of light, conventional sensor elements for optically determining the concentrations of substances contained in gaseous and liquid samples, featuring an indicator layer with one or more indicator substances, are not well suited for use with microanalysis equipment, nor are they easy to mass-produce. These disadvantages are eliminated by integrating on the carrier layer (1) at least one photosensitive element (3) and its electric contact leads in planar arrangement, and by establishing optical contact between the indicator substance (7, 7') of the indicator layer (6) stimulated by the excitation radiation (11), and the photosensitive elements (3).
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公开(公告)号：US5039490A
公开(公告)日：1991-08-13
申请号：US40163
申请日：1987-04-17
申请人： Hermann Marsoner , Herbert Kroneis , Hellfried Karpf , Otto S. Wolfbeis , Helmut List , Alfred Leitner
发明人： Hermann Marsoner , Herbert Kroneis , Hellfried Karpf , Otto S. Wolfbeis , Helmut List , Alfred Leitner
CPC分类号： G01N21/77 , G01N21/255 , G01N2021/174 , G01N2021/7786 , G01N21/6428 , G01N21/81 , G01N2201/0621 , G01N2201/0622
摘要： Due to the size of the devices used for the excitation and measuring of light, conventional sensor elements for optically determining the concentrations of substances contained in gaseous and liquid samples, featuring an indicator layer with one or more indicator substances, are not well suited for use with microanalysis equipment, nor are they easy to mass-produce. These disadvantages are eliminated by using a unitary sensor element having a carrier layer, at least one photosensitive element with electric contact leads in contact with the carrier layer, and an indicator layer containing an indicator substance.
摘要翻译： 由于用于激发和测量光的装置的尺寸，用于光学确定气态和液体样品中所含物质浓度的常规传感器元件，其特征在于具有一个或多个指示剂物质的指示剂层，不太适用于 使用微量分析设备，也不易于批量生产。 这些缺点通过使用具有载体层的单一传感器元件，至少一个具有电接触引线与载体层接触的感光元件以及含有指示物质的指示剂层来消除。
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公开(公告)号：US4755667A
公开(公告)日：1988-07-05
申请号：US40628
申请日：1987-04-17
CPC分类号： G02B6/34 , G01N21/7703 , G02B6/42 , G01N2201/0622
摘要： A sensor element for use in determining the concentrations of substances contained in gaseous and liquid samples includes a carrier layer and an indicator layer containing one or more indicator substances whose optical properties change depending on the concentration of the substances to be measured, the carrier layer being provided with at least one photosensitive element with electrical contacts in planar arrangement, the indicator layer acting as a waveguide for excitation radiation coupled therein by an optical element.
摘要翻译： 用于确定气态和液体样品中所含物质浓度的传感器元件包括载体层和含有一种或多种指示物质的指示剂层，其指示剂物质的光学性质根据待测物质的浓度而变化，载体层为 设置有至少一个具有平面布置的电触头的感光元件，所述指示器层用作通过光学元件耦合在其中的激发辐射的波导。
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公开(公告)号：USRE37412E1
公开(公告)日：2001-10-16
申请号：US09271164
申请日：1999-03-17
IPC分类号： G01N2175
CPC分类号： G01N21/77 , G01N21/78 , G01N2021/7723 , G01N2021/773 , G01N2021/7779
摘要： An optochemical sensor for measuring concentrations of analytes is provided with a reactive matrix preferably made of polymeric material capable of swelling. Further provided are a mirror layer and a layer of a plurality of discrete islands that are electrically conductive, between which layers the reactive matrix is positioned, the diameter of the islands being smaller than the wavelength of the light employed for monitoring and evaluation.
摘要翻译： 用于测量分析物浓度的光化学传感器具有优选由能够溶胀的聚合材料制成的反应性基质。 进一步提供了镜面层和导电的多个离散岛的层，反射矩阵位于该层之间，岛的直径小于用于监测和评估的光的波长。
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5.发明授权Optochemical fluorescence sensor and method for measuring the concentration of at least one analyte in a sample 失效光化学荧光传感器和测量样品中至少一种分析物浓度的方法
公开(公告)号：US5866433A
公开(公告)日：1999-02-02
申请号：US616153
申请日：1996-03-14
IPC分类号： G01N21/64 , G01N21/78 , G01N33/487 , G01N33/543 , G01N33/553
CPC分类号： G01N21/648 , G01N21/6428 , G01N33/54373 , G01N2021/6432 , Y10S435/808 , Y10S436/805 , Y10S436/807
摘要： An optochemical fluorescence sensor with a biorecognitive layer for measuring the concentration of one or more analytes in a sample is provided with at least one island layer which is applied on a sensor substrate. The islands of the island layer are in the form of electrically-conductive material and have a diameter of less than 300 nm, the biorecognitive layer being directly applied on the island layer or bound via a spacer film. In addition, an analyte-specific fluorescent compound is provided which may be added to the sample or is provided in the sensor itself. The biorecognitive layer can bind the analyte to be measured directly or by means of analyte-binding molecules, the originally low quantum yield of the fluorescent compound increasing strongly in the vicinity of the island layer.
摘要翻译： 具有用于测量样品中一种或多种分析物的浓度的生物识别层的光化学荧光传感器设置有施加在传感器基底上的至少一个岛层。 岛层的岛是导电材料的形式，其直径小于300nm，生物识别层直接施加在岛层上或通过间隔膜结合。 此外，提供了可以添加到样品中或者设置在传感器本身中的分析物特异性荧光化合物。 生物识别层可以直接结合要测量的分析物或通过分析物结合分子结合，荧光化合物的原始低量子产率在岛层附近强烈增加。
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公开(公告)号：US5611998A
公开(公告)日：1997-03-18
申请号：US419615
申请日：1995-04-10
CPC分类号： G01N21/77 , G01N21/78 , G01N2021/7723 , G01N2021/773 , G01N2021/7779
摘要： An optochemical sensor for measuring concentrations of analytes is provided with a reactive matrix preferably made of polymeric material capable of swelling. Further provided are a mirror layer and a layer of a plurality of discrete islands that are electrically conductive, between which layers the reactive matrix is positioned, the diameter of the islands being smaller than the wavelength of the light employed for monitoring and evaluation.
摘要翻译： 用于测量分析物浓度的光化学传感器具有优选由能够溶胀的聚合材料制成的反应性基质。 进一步提供了镜面层和导电的多个离散岛的层，反射矩阵位于该层之间，岛的直径小于用于监测和评估的光的波长。
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