公开(公告)号：US20240288369A1

公开(公告)日：2024-08-29

申请号：US18659638

申请日：2024-05-09

Applicant: Uster Technologies AG

Inventor： Peyman H. Dehkordi ,  Kent A. Rinehart ,  David Dickson McAlister, III

IPC: G01N21/64 ,  G01N21/17 ,  G01N21/25 ,  G01N21/27 ,  G01N21/31 ,  G01N21/47 ,  G01N21/55 ,  G01N33/36

CPC classification number: G01N21/6456 ,  G01N21/256 ,  G01N21/276 ,  G01N21/31 ,  G01N21/55 ,  G01N33/367 ,  G01N2021/174 ,  G01N2021/178 ,  G01N2021/3155 ,  G01N2021/4766 ,  G01N2021/6423 ,  G01N2021/6471

Abstract: An apparatus (100) for optically characterizing a textile sample (106) comprises a presentation subsystem (102) comprising a viewing window (108). A radiation subsystem (114) comprises a radiation source (120) for directing a first, ultraviolet radiation (122) and a second, visible radiation (123) toward the sample (106), and causing the sample (106) to produce a fluorescent radiation (124) and a reflected radiation (125). A sensing subsystem (126) comprises an imager (130) for capturing the fluorescent radiation (124) and the reflected radiation (125) in an array of pixels (408). A control subsystem (132) comprises a processor (136) for controlling the presentation subsystem (102), the radiation subsystem (114), and the sensing subsystem (126), and for creating a fluorescent and reflected radiation image (400) containing both spectral information and spatial information in regard to the fluorescent radiation (124) and the reflected radiation (125).

公开(公告)号：US20180067087A1

公开(公告)日：2018-03-08

申请号：US15653535

申请日：2017-07-19

Applicant: TOSHIBA TEC KABUSHIKI KAISHA

Inventor： Ryozo AKIYAMA

IPC: G01N31/22 ,  G01N21/17 ,  G01N1/28 ,  C07C63/331

CPC classification number: G01N31/22 ,  C07C63/331 ,  G01N1/28 ,  G01N21/1717 ,  G01N33/582 ,  G01N33/68 ,  G01N2021/174

Abstract: An amine compound detection marker has a composition that allows for detection of an amine compound, in particular histamine, with high sensitivity. The composition of the amine compound detection marker comprises a solvent and an aggregate phosphor that aggregates as a result of coexistence with an amine compound when an extract liquid of the analyte containing the amine compound comes into contact with the composition. The aggregate phosphor is a tetraarylethene compound represented by the following formula (1).

公开(公告)号：US20170356848A1

公开(公告)日：2017-12-14

申请号：US15528123

申请日：2015-11-24

Applicant: GE HEALTHCARE BIO-SCIENCES AB

Inventor： Hanno Ehring

IPC: G01N21/64 ,  G01N21/05 ,  G01N21/33 ,  G01J3/42 ,  G01N21/17 ,  G01J3/44

CPC classification number: G01N21/645 ,  G01J3/42 ,  G01J3/4406 ,  G01J2003/421 ,  G01N21/05 ,  G01N21/33 ,  G01N2021/1736 ,  G01N2021/1738 ,  G01N2021/174 ,  G01N2021/6482 ,  G01N2021/6484 ,  G01N2021/6491 ,  G01N2201/0696

Abstract: Disclosed is apparatus (1) for measuring fluorescence and absorbance of a substance in a sample, said apparatus (1) comprising: a flow cell (2) for containing a sample, a first light source (3), a first conductor (5) for transmitting light from the first light source (3) to the flow cell (2) for irradiating a sample contained therein, a second conductor (7) for transmitting light from the flow cell (2) to a sample detector (9) arranged to detect an electromagnetic radiation that has passed through said cell (2), and a processing unit (16) arranged to receive a first signal (31) from a reference detector (15) and a second signal (32) from the sample detector (9) and to determine an absorbance based on said first and second signals (31,32), said apparatus (1) further comprising a second light source (4), a third conductor (6) for transmitting light from the second light source (4) to the cell (2) and wherein the sample detector (9) is further arranged to also detect fluorescence signals in the light that has passed through the flow cell (2). The invention also relates to a method for measuring the absorbance and the fluorescence of a substance in a sample.

公开(公告)号：US20170307528A1

公开(公告)日：2017-10-26

申请号：US15138660

申请日：2016-04-26

Applicant: Molecular Devices, LLC

Inventor： Josef J. Atzler ,  Michael Katzlinger ,  Klaus Wagner

IPC: G01N21/64

CPC classification number: G01N21/6428 ,  G01N21/6408 ,  G01N21/6445 ,  G01N21/645 ,  G01N2021/174 ,  G01N2201/061 ,  G01N2201/063

Abstract: In an optical-based sample analysis, for example fluorescence-based or absorbance-based measurement, a selection is made between a first excitation light path and a second excitation light path. The first excitation light path directs excitation light from a light source, through an excitation monochromator, through an excitation filter, and to a sample. The second excitation light path directs excitation light from the light source, through the excitation filter, and to the sample while bypassing the excitation monochromator. Excitation light generated by the light source is transmitted along either the first excitation light path or the second excitation light path in accordance with the selection made, thereby irradiating the sample. In response the sample produces emission light (transmitted light in the case of absorbance measurements), which is transmitted to and measured by a light detector.

公开(公告)号：US09127245B2

公开(公告)日：2015-09-08

申请号：US12738045

申请日：2008-11-27

Applicant: Takeshi Miyazaki ,  Kohei Watanabe ,  Toshio Tanaka ,  Yasuhito Shimada ,  Norihiro Nishimura

Inventor： Takeshi Miyazaki ,  Kohei Watanabe ,  Toshio Tanaka ,  Yasuhito Shimada ,  Norihiro Nishimura

IPC: C12M3/00 ,  C12M1/12 ,  C12M1/42 ,  C12M1/32 ,  G01N21/64 ,  G01N21/03 ,  G01N21/17

CPC classification number: C12M21/06 ,  C12M23/12 ,  C12M25/01 ,  C12M25/06 ,  C12M35/08 ,  G01N21/6456 ,  G01N2021/0339 ,  G01N2021/0342 ,  G01N2021/0378 ,  G01N2021/174

Abstract: A method of arranging a large number of living bodies, such as cells, embryos, or organisms rapidly, individually, and one by one, a holding sheet for the method, and a device for processing the living bodies. The method of holding living bodies includes using a sheet in which multiple through-holes with a size capable of holding one of the target living bodies, but not capable of holding two or more of the living bodies, are provided, to thereby arrange and hold the living bodies one by one in the multiple through-holes in the sheet together with a liquid.

Abstract translation: 快速，单独地，逐个地排列大量生物体如细胞，胚胎或生物的方法，用于该方法的保持片，以及用于处理活体的装置。 保持生物体的方法包括使用其中设置有能够容纳目标生物体之一但不能容纳两个或多个生物体的尺寸的多个通孔的片材，从而布置和保持 活体在片材中的多个通孔中一个一个地连同液体。

公开(公告)号：US08585880B2

公开(公告)日：2013-11-19

申请号：US13246090

申请日：2011-09-27

Applicant: Sayandev Chatterjee ,  Samuel A. Bryan ,  Cynthia A. Schroll ,  William R. Heineman

Inventor： Sayandev Chatterjee ,  Samuel A. Bryan ,  Cynthia A. Schroll ,  William R. Heineman

IPC: G01N21/75

CPC classification number: G01N21/17 ,  G01N21/64 ,  G01N27/305 ,  G01N2021/1721 ,  G01N2021/174

Abstract: An apparatus and method of simultaneous spectroelectrochemical analysis is disclosed. A transparent surface is provided. An analyte solution on the transparent surface is contacted with a working electrode and at least one other electrode. Light from a light source is focused on either a surface of the working electrode or the analyte solution. The light reflected from either the surface of the working electrode or the analyte solution is detected. The potential of the working electrode is adjusted, and spectroscopic changes of the analyte solution that occur with changes in thermodynamic potentials are monitored.

Abstract translation: 公开了同步光谱电化学分析的装置和方法。 提供透明表面。 透明表面上的分析物溶液与工作电极和至少一个其他电极接触。 来自光源的光聚焦在工作电极或分析物溶液的表面上。 检测从工作电极的表面或分析物溶液反射的光。 调整工作电极的电位，并监测随着热力学势的变化而发生的分析物溶液的光谱变化。

公开(公告)号：US08379193B2

公开(公告)日：2013-02-19

申请号：US12802994

申请日：2010-06-17

Applicant: Charles W. Gardner, Jr. ,  Matthew Nelson

Inventor： Charles W. Gardner, Jr. ,  Matthew Nelson

IPC: G01N21/00

CPC classification number: G01J3/02 ,  G01J3/0221 ,  G01J3/0264 ,  G01J3/2823 ,  G01J3/36 ,  G01J3/44 ,  G01N21/6456 ,  G01N21/65 ,  G01N2021/1738 ,  G01N2021/174 ,  G01N2021/1744

Abstract: The present disclosure provides for a system and method for detecting explosives and other materials in a sample scene. First interacted photons are produced from a target area wherein the first interacted photons are generated via solar radiation. The first interacted photons are assessed to thereby generate a SWIR hyperspectral image. The SWIR hyperspectral image is analyzed to identify an area of interest likely of comprising an explosive material. The area of interest is illuminated using laser light illumination to generate second interacted photons from the area of interest. These second interacted photons are assessed to determine whether it not an explosive material is present in the area of interest. The system and method may be configured in standoff, OTM, static and UGV configurations.

Abstract translation: 本公开提供了用于在样本场景中检测爆炸物和其他材料的系统和方法。 从目标区域产生第一相互作用的光子，其中通过太阳辐射产生第一相互作用的光子。 评估第一相互作用的光子，从而产生SWIR高光谱图像。 分析SWIR高光谱图像以识别可能包含爆炸物质的感兴趣区域。 使用激光照明来照亮感兴趣区域，以从感兴趣区域产生第二相互作用的光子。 评估这些第二个相互作用的光子，以确定在感兴趣区域中是否存在爆炸物质。 系统和方法可以配置为隔离，OTM，静态和UGV配置。

公开(公告)号：US20040132196A1

公开(公告)日：2004-07-08

申请号：US10655739

申请日：2003-09-05

Inventor： Toshihiro Mizukami ,  Yusuke Mori ,  Kanako Horisaka ,  Sunao Atogami

IPC: G01N033/48 ,  G01N021/64

CPC classification number: G01N21/51 ,  G01N15/1456 ,  G01N21/645 ,  G01N2015/0076 ,  G01N2015/1486 ,  G01N2021/1734 ,  G01N2021/174 ,  G01N2021/178 ,  G01N2021/4707 ,  Y10T436/10 ,  Y10T436/101666

Abstract: Methods and devices are described for monitoring a therapeutic effect in a red blood cell-related disease by detecting the size of a reticulocyte using a full-automatic blood cell counting device.

Abstract translation: 描述了用于通过使用全自动血细胞计数装置检测网织红细胞的大小来监测红细胞相关疾病的治疗效果的方法和装置。

公开(公告)号：US5219527A

公开(公告)日：1993-06-15

申请号：US758291

申请日：1991-08-28

Applicant: Henry K. Hui ,  Charles S. Bankert

Inventor： Henry K. Hui ,  Charles S. Bankert

IPC: G01N33/49 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1459 ,  G01N21/64 ,  G01N21/77 ,  G01N21/78 ,  G01N21/82

CPC classification number: G01N21/643 ,  G01N21/7703 ,  G01N2021/174 ,  G01N2021/6434 ,  G01N2021/772 ,  G01N2021/773 ,  G01N2021/775 ,  G01N2021/7786

Abstract: A sensor element includes an analyte-permeable matrix which supports and maintains a sensing solution containing an analyte-sensitive indicator substance in a plurality of tiny vesicles. The sensor element is prepared by combining the sensing solution with an emuslifier that renders the solution dispersed within the matrix material. The sensing solution remains suspended in these dispersed vesicles after the matrix solidifies. A sensor element made in accordance with the present invention may be placed at the end of an optical fiber.

公开(公告)号：US5047351A

公开(公告)日：1991-09-10

申请号：US351315

申请日：1989-05-10

Applicant: Hajime Makiuchi ,  Yuzo Iwata ,  Kikuo Hirai ,  Kenji Murabayashi

Inventor： Hajime Makiuchi ,  Yuzo Iwata ,  Kikuo Hirai ,  Kenji Murabayashi

IPC: C12Q1/00 ,  G01N21/27 ,  G01N21/75 ,  G01N21/78 ,  G01N31/22 ,  G01N33/52

CPC classification number: C12Q1/00 ,  G01N21/272 ,  G01N33/521 ,  G01N2021/174 ,  G01N21/78

Abstract: A method for shortening the analysis time, without adversely affecting the accuracy in the colorimetric analysis of an analyte. The method including the steps of:(a) Measuring the optical density for two or more times at suitable time intervals after the beginning of reaction to follow the variation of optical density,(b) Judging based upon the optical density obtained at the earlier measurement whether the reaction is to be further continued or not,(c) When it is judged that the continuation of the reaction is not necessary in terms of analytical accuracy, selecting the calibration curve corresponding to the reaction time,(d) While, when it is judged that the continuation of the reaction is necessary, further continuing the reaction, and(e) Repeating steps (b) and (d) until the judgement that the continuation of the reaction is not necessary is obtained.

Abstract translation: 用于缩短分析时间的方法，而不会不利地影响分析物的比色分析的准确性。 该方法包括以下步骤：（a）在反应开始后以合适的时间间隔测量光密度两次或更多次，以遵循光密度的变化，（b）基于在较早测量时获得的光密度 反应是否进一步持续，（c）当判断在分析精度方面不需要继续反应时，选择与反应时间对应的校准曲线，（d）当 判断反应的持续是必要的，进一步继续反应，（e）重复步骤（b）和（d），直到判断出不需要反应的延续为止。