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    Sensor element for determination of concentration of substances
    3.
    发明授权
    Sensor element for determination of concentration of substances 失效
    用于测定物质浓度的传感器元件

    公开(公告)号：US4755667A

    公开(公告)日：1988-07-05

    申请号：US40628

    申请日：1987-04-17

    申请人： Hermann Marsoner ,  Hellfried Karpf ,  Alfred Leitner

    发明人： Hermann Marsoner ,  Hellfried Karpf ,  Alfred Leitner

    IPC分类号： G01N21/64 ,  G01N21/27 ,  G01N21/77 ,  G02B6/34 ,  G02B6/42 ,  G01N21/00

    CPC分类号： G02B6/34 ,  G01N21/7703 ,  G02B6/42 ,  G01N2201/0622

    摘要： A sensor element for use in determining the concentrations of substances contained in gaseous and liquid samples includes a carrier layer and an indicator layer containing one or more indicator substances whose optical properties change depending on the concentration of the substances to be measured, the carrier layer being provided with at least one photosensitive element with electrical contacts in planar arrangement, the indicator layer acting as a waveguide for excitation radiation coupled therein by an optical element.

    摘要翻译： 用于确定气态和液体样品中所含物质浓度的传感器元件包括载体层和含有一种或多种指示物质的指示剂层，其指示剂物质的光学性质根据待测物质的浓度而变化，载体层为 设置有至少一个具有平面布置的电触头的感光元件，所述指示器层用作通过光学元件耦合在其中的激发辐射的波导。

    Sensor membrane of an optical sensor
    4.
    发明授权
    Sensor membrane of an optical sensor 失效
    传感器的传感器膜

    公开(公告)号：US6139798A

    公开(公告)日：2000-10-31

    申请号：US843296

    申请日：1997-04-14

    申请人： Ingo Klimant ,  Hellfried Karpf ,  Otto S. Wolfbeis

    发明人： Ingo Klimant ,  Hellfried Karpf ,  Otto S. Wolfbeis

    IPC分类号： G01N21/77 ,  G01N21/17 ,  G01N21/62 ,  G01N21/64 ,  G01N31/22

    CPC分类号： G01N31/225 ,  G01N31/223 ,  Y10T436/207497

    摘要： The sensor membrane of an optical sensor for detection of O.sub.2, H.sub.2 O.sub.2, SO.sub.2 or halogenated hydrocarbons in a sample contains an indicator substance that is homogeneously immobilized in the polymer matrix of the sensor membrane and is, at least indirectly, in contact with the sample, changing at least one of its optical properties upon a change of the parameter to be measured. The indicator substance contains an inorganic salt of a transition metal complex with .alpha.-diimine ligands. The indicator substance is homogeneously distributed in the polymer matrix, which essentially consists of at least one substance belonging to the group of cellulose derivatives, polystyrenes, polytetrahydrofuranes, or their respective derivatives.

    摘要翻译： 用于检测样品中的O 2，H 2 O 2，SO 2或卤代烃的光学传感器的传感器膜包含均匀地固定在传感器膜的聚合物基质中的指示物质，并且至少间接地与样品接触， 在要测量的参数的变化时改变其光学特性中的至少一个。 指示物质含有与α-二亚胺配体的过渡金属络合物的无机盐。 指示剂物质均匀分布在聚合物基质中，其基本上由属于纤维素衍生物，聚苯乙烯，聚四氢呋喃或它们各自的衍生物的至少一种物质组成。

    Device for measuring chemical and physical parameters of a liquid or gaseous medium
    5.
    发明授权
    Device for measuring chemical and physical parameters of a liquid or gaseous medium 失效
    用于测量液体或气体介质的化学和物理参数的装置

    公开(公告)号：US5128019A

    公开(公告)日：1992-07-07

    申请号：US437202

    申请日：1989-11-16

    申请人： Hellfried Karpf ,  Helmut Offenbacher ,  Erich Kleinhappl ,  Hermann Marsoner ,  Ewald Jobstl

    发明人： Hellfried Karpf ,  Helmut Offenbacher ,  Erich Kleinhappl ,  Hermann Marsoner ,  Ewald Jobstl

    IPC分类号： G01N21/64 ,  G01N21/25 ,  G01N21/77 ,  G01N21/78 ,  G01N33/49

    CPC分类号： G01N21/7703 ,  G01N21/251

    摘要： In order to reduce the measuring volume in a device for measuring chemical and physical parameters of liquid or gaseous media by means of optical sensor elements whose optodes may be replaced easily, a measuring unit with a sample channel is provided which may be inserted into a supporting frame of the device and which may be connected to ingoing and outgoing sample lines via capillary bores. The measuring unit contains a sensor carrier forming the boundary of the sample channel on one side, which sensor carrier has bores holding the optodes. The indicator film of each individual optode is situated in the plane of the sensor carrier facing the sample channel.

    摘要翻译： 为了减少用于测量液体或气体介质的化学和物理参数的装置中的测量体积，该光学传感器元件可以容易地替换其光学部件，可以提供具有样品通道的测量单元，其可插入支撑 框架，并且可以通过毛细管孔连接到入口和出口的样品管线。 测量单元包含传感器载体，该传感器载体在一侧形成样品通道的边界，该传感器载体具有保持光电极的孔。 每个单独光电的指示膜位于传感器载体面向样品通道的平面内。

    Device and method for management of operating materials and/or supplies of an analyzer and analyzing system
    7.
    发明申请
    Device and method for management of operating materials and/or supplies of an analyzer and analyzing system 审中-公开
    用于管理分析仪和分析系统的操作材料和/或供应的装置和方法

    公开(公告)号：US20070118422A1

    公开(公告)日：2007-05-24

    申请号：US11652046

    申请日：2007-01-11

    申请人： Hans Berger ,  Ulrich Kanter ,  Hellfried Karpf ,  Werner Ziegler

    发明人： Hans Berger ,  Ulrich Kanter ,  Hellfried Karpf ,  Werner Ziegler

    IPC分类号： G07G1/00 ,  G06F17/30

    CPC分类号： G06Q10/087

    摘要： An automation process for the management of operating materials and/or supplies of an analyzer or analyzing system, preferably for applications in medical, environmental or food technology, comprising the following steps: (a) automatic recording of data on operating materials and/or supplies, in particular type and maximum useful life of the operating materials used, as well as types, expiry dates and quantities of the required supplies, (b) entering the desired frequency of analysis, or automatic calculation of the estimated frequency of analysis from past frequencies of use of the analyzer or analyzing system, (c) automatic calculation of the operating materials and/or supplies required per unit of time, based on the data obtained in steps (a) and (b), (d) determining an optimum point in time for ordering the required operating materials and/or supplies, (e) automated ordering of the operating materials and/or supplies via a device for remote data transmission, preferably via an internet connection.

    摘要翻译： 用于管理分析器或分析系统的操作材料和/或供应的自动化过程，优选地用于医疗，环境或食品技术中的应用，包括以下步骤：（a）自动记录操作材料和/或用品上的数据 ，特别是使用的操作材料的类型和最大使用寿命，以及所需耗材的类型，到期日期和数量，（b）输入所需的分析频率，或自动计算过去频率的分析估计频率 使用分析器或分析系统，（c）基于步骤（a）和（b）中获得的数据，（d）确定最佳点，自动计算每单位时间所需的操作材料和/或耗材 及时为订购所需的操作材料和/或耗材，（e）经由用于远程数据传输的设备的操作材料和/或电源的自动排序，优选地经由 rnet连接。

    Optical indicator for determining the activity of an ion in a sample
    8.
    发明授权
    Optical indicator for determining the activity of an ion in a sample 失效
    用于确定样品中离子活性的光学指示剂

    公开(公告)号：US5723340A

    公开(公告)日：1998-03-03

    申请号：US645891

    申请日：1996-05-14

    申请人： Hellfried Karpf

    发明人： Hellfried Karpf

    IPC分类号： G01N21/78 ,  C09K11/06 ,  G01N31/22 ,  G01N33/84 ,  G01N33/86 ,  G01N33/20

    CPC分类号： G01N31/22 ,  G01N33/84

    摘要： An optical indicator for determining the activity of an ion in a sample is provided with an ionophor which is capable of selectively binding the ion to be measured. The ionophor has at least two functional groups that can form an electron donor acceptor (EDA) complex, the complex bond being broken up by the attachment of the ion to be determined. This will lead to a change in at least one of the measurable optical properties of the indicator in dependence on the activity of the ion to be measured.

    摘要翻译： 用于测定样品中的离子的活性的光学指示器具有能够选择性地结合待测量的离子的离子体。 电离子具有至少两个可以形成电子给体受体（EDA）络合物的官能团，复合键被待测定的离子的附着分解。 这将导致指示剂的至少一个可测量的光学性质根据待测离子的活性而发生变化。

    Method for detecting biological activities in a specimen
    10.
    发明授权
    Method for detecting biological activities in a specimen 失效
    检测标本中生物活性的方法

    公开(公告)号：US5372936A

    公开(公告)日：1994-12-13

    申请号：US108540

    申请日：1993-08-19

    申请人： Robert Fraatz ,  Ewald Joebstl ,  Hellfried Karpf

    发明人： Robert Fraatz ,  Ewald Joebstl ,  Hellfried Karpf

    IPC分类号： C12M1/34 ,  C12Q1/04 ,  G01N21/77 ,  G01N21/85 ,  G01N21/76

    CPC分类号： C12Q1/04 ,  G01N21/77 ,  G01N2021/1738 ,  G01N21/8507 ,  G01N2201/08 ,  Y10S435/805 ,  Y10S435/817 ,  Y10S435/968 ,  Y10S436/80 ,  Y10S436/805

    摘要： A method, a sensor and apparatus for detecting biological activities in a specimen, for example in a blood sample, are provided in which a sealable container is sealed with a culture medium therein into which the sample is introduced, metabolic processes are enhanced in the presence of microorganisms in the sample and changes taking place in the concentrations of the substances. Such processes are detected and monitored with an excitation and detection assembly assigned to concentration sensors, in the form of optodes which are optically coupled to the excitation and detection assembly and to thereby to an evaluation unit for determining concentration changes of the substances over time as indications of the presence of microorganisms.

    摘要翻译： 提供了一种用于检测样品中例如血液样品中生物活性的方法，传感器和装置，其中可密封容器用其中引入样品的培养基密封，代谢过程在存在下增强 的样品中的微生物和发生在物质浓度上的变化。 通过分配给浓度传感器的激发和检测组件来检测和监测这些过程，所述浓度传感器以光学形式与光学耦合到激发和检测组件并由此到达用于确定物质随时间的浓度变化的指示 微生物的存在。