摘要:
The present invention provides a vaccine composition for transnasal mucous membrane administration, which contains an influenza virus antigen, polyriboinosinic polyribocytidylic acid (poly (I:C)) or a derivative thereof and a carboxyvinyl polymer. The present invention also provides a prophylactic method of influenza, including a step of administering the vaccine composition at least once to the nasal mucosa of a subject in need thereof.
摘要:
The present invention provides a vaccine composition for transnasal mucous membrane administration, which contains an influenza virus antigen, polyriboinosinic polyribocytidylic acid (poly (I:C)) or a derivative thereof and a carboxyvinyl polymer. The present invention also provides a prophylactic method of influenza, including a step of administering the vaccine composition at least once to the nasal mucosa of a subject in need thereof.
摘要:
A fluid container according to the present invention includes a container body having upper and lower openings, and further having a shoulder member and a side wall which extend between the upper and lower openings. The fluid container also includes a spacer abutting on the shoulder member of the container body, and a slidable valve slidably moving along an inner surface of the side wall of the container body in a hermetically sealed manner. The slidable valve defines a container space for holding fluid, in conjunction with the side wall of the container body. Further, a bottom cover is provided for covering across the lower opening of the container body. The spacer and the slidable valve include a spacer surface and a valve surface, respectively, which oppose to each other and are inclined at tilt angles between 5 and 30 degrees relative to a horizontal surface. Therefore, an airless fluid dispensing system using the fluid container securely prevents a small air bubble from being trapped in the container body when filled in with the fluid, thereby to dispense a constant dosage without requiring undesired pumping actions prior to actual use.
摘要:
The present invention provides a sprayable gel-type skin/mucosa-adhesive preparation comprising a gel formulation which contains an active pharmaceutical ingredient in a gel base material comprising a skin/mucosa-adhesive agent and an administration system comprising the preparation.
摘要:
The present invention provides a sprayable gel-type skin/mucosa-adhesive preparation comprising a gel formulation which contains an active pharmaceutical ingredient in a gel base material comprising a skin/mucosa-adhesive agent and an administration system comprising the preparation.
摘要:
A fluid container according to the present invention includes a container body having upper and lower openings, and further having a shoulder member and a side wall which extend between the upper and lower openings. The fluid container also includes a spacer abutting on the shoulder member of the container body, and a slidable valve slidably moving along an inner surface of the side wall of the container body in a hermetically sealed manner. The slidable valve defines a container space for holding fluid, in conjunction with the side wall of the container body. Further, a bottom cover is provided for covering across the lower opening of the container body. The spacer and the slidable valve include a spacer surface and a valve surface, respectively, which oppose to each other and are inclined at tilt angles between 5 and 30 degrees relative to a horizontal surface. Therefore, an airless fluid dispensing system using the fluid container securely prevents a small air bubble from being trapped in the container body when filled in with the fluid, thereby to dispense a constant dosage without requiring undesired pumping actions prior to actual use.
摘要:
The present invention provides a sprayable gel-type skin/mucosa-adhesive preparation comprising a gel formulation which contains an active pharmaceutical ingredient in a gel base material comprising a skin/mucosa-adhesive agent and an administration system comprising the preparation.