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    Method for detecting an endogenous biomolecule
    1.
    发明授权
    Method for detecting an endogenous biomolecule 失效
    检测内源性生物分子的方法

    公开(公告)号：US08722420B2

    公开(公告)日：2014-05-13

    申请号：US13504890

    申请日：2010-10-29

    申请人： Hideo Utsumi ,  Fuminori Hyodo ,  Kazuhiro Ichikawa

    发明人： Hideo Utsumi ,  Fuminori Hyodo ,  Kazuhiro Ichikawa

    IPC分类号： G01N24/00

    CPC分类号： A61K49/20 ,  G01R33/48 ,  G01R33/485 ,  G01R33/5601 ,  G01R33/60 ,  G01R33/62 ,  Y10T436/141111 ,  Y10T436/142222 ,  Y10T436/200833 ,  Y10T436/24

    摘要： Provided is a method for the real-time visualization of an endogenous biomolecule to clarify the mechanisms of various diseases and enable diagnosis and treatment of these diseases. Specifically provided is a novel method for visualizing an endogenous biomolecule by using a magnetic resonance method (including Overhauser MRI and the electron spin resonance method). The aforesaid visualization method, whereby an endogenous biomolecule is visualized on a real-time basis, comprises: a step for treating a living organism to be examined by a magnetic resonance method and thus acquiring data of the endogenous biomolecule; a step for processing the data of the endogenous biomolecule thus obtained to give imaging data; and a step for displaying the imaging data thus obtained.

    摘要翻译： 提供了一种内源性生物分子的实时可视化方法，以澄清各种疾病的机制，并能够诊断和治疗这些疾病。 具体提供的是通过使用磁共振法（包括Overhauser MRI和电子自旋共振法）来观察内源性生物分子的新方法。 上述可视化方法，其中内生生物分子在实时的基础上可视化，包括：通过磁共振方法处理待检查的活生物体，从而获取内源性生物分子的数据的步骤; 用于处理由此获得的内源性生物分子的数据以提供成像数据的步骤; 以及用于显示由此获得的成像数据的步骤。

    Method for Detecting Endogenous Biomolecules
    2.
    发明申请
    Method for Detecting Endogenous Biomolecules 失效
    检测内源性生物分子的方法

    公开(公告)号：US20120276644A1

    公开(公告)日：2012-11-01

    申请号：US13504890

    申请日：2010-10-29

    申请人： Hideo Utsumi ,  Fuminori Hyodo ,  Kazuhiro Ichikawa

    发明人： Hideo Utsumi ,  Fuminori Hyodo ,  Kazuhiro Ichikawa

    IPC分类号： A61B5/055 ,  G01N24/08

    CPC分类号： A61K49/20 ,  G01R33/48 ,  G01R33/485 ,  G01R33/5601 ,  G01R33/60 ,  G01R33/62 ,  Y10T436/141111 ,  Y10T436/142222 ,  Y10T436/200833 ,  Y10T436/24

    摘要： Provided is a method for the real-time visualization of an endogenous biomolecule to clarify the mechanisms of various diseases and enable diagnosis and treatment of these diseases. Specifically provided is a novel method for visualizing an endogenous biomolecule by using a magnetic resonance method (including Overhauser MRI and the electron spin resonance method). The aforesaid visualization method, whereby an endogenous biomolecule is visualized on a real-time basis, comprises: a step for treating a living organism to be examined by a magnetic resonance method and thus acquiring data of the endogenous biomolecule; a step for processing the data of the endogenous biomolecule thus obtained to give imaging data; and a step for displaying the imaging data thus obtained.

    摘要翻译： 提供了一种内源性生物分子的实时可视化方法，以澄清各种疾病的机制，并能够诊断和治疗这些疾病。 具体提供的是通过使用磁共振法（包括Overhauser MRI和电子自旋共振法）来观察内源性生物分子的新方法。 上述可视化方法，其中内生生物分子在实时的基础上可视化，包括：通过磁共振方法处理待检查的活生物体，从而获取内源性生物分子的数据的步骤; 用于处理由此获得的内源性生物分子的数据以提供成像数据的步骤; 以及用于显示由此获得的成像数据的步骤。

    MEASUREMENT DEVICE AND MEASUREMENT METHOD
    3.
    发明申请
    MEASUREMENT DEVICE AND MEASUREMENT METHOD 有权
    测量装置和测量方法

    公开(公告)号：US20110112395A1

    公开(公告)日：2011-05-12

    申请号：US13002920

    申请日：2009-07-07

    申请人： Kazuhiro Ichikawa ,  Hideo Utsumi

    发明人： Kazuhiro Ichikawa ,  Hideo Utsumi

    IPC分类号： A61B5/055

    CPC分类号： A61B5/0555 ,  A61B5/0035 ,  A61B2503/40 ,  G01N24/10 ,  G01R33/3806 ,  G01R33/381 ,  G01R33/3815 ,  G01R33/383 ,  G01R33/481 ,  G01R33/4812 ,  G01R33/56375 ,  G01R33/56383 ,  G01R33/60 ,  G01R33/62

    摘要： A measurement device and measurement method make it possible to eliminate the load generated by stopping on a measurement subject that is moved among multiple magnetic field generating devices. The measurement device includes a first external magnetic field generating device that generates a magnetic field of a set size, a second external magnetic field generating device that generates a magnetic field of a size that differs from that of the magnetic field of the first external magnetic field generating device, a rotating table that causes the subject of measurement to pass in sequence through the magnetic fields of the first and second external magnetic field generating devices by causing the subject of measurement to move rotationally, and an OMRI measurement processing part and MRI measurement processing part that measures images such as functional images or structural images of the subject of measurement while it is being moved rotationally by the rotating table.

    摘要翻译： 测量装置和测量方法可以消除由在多个磁场产生装置之间移动的测量对象停止而产生的负载。 测量装置包括产生一定尺寸的磁场的第一外部磁场产生装置，产生尺寸与第一外部磁场的磁场的磁场不同的磁场的第二外部磁场产生装置 生成装置，通过使测量对象旋转移动使得测量对象依次通过第一外部磁场产生装置和第二外部磁场产生装置的磁场的旋转台，以及OMRI测量处理部分和MRI测量处理 在通过旋转台被旋转移动的同时测量诸如测量对象的功能图像或结构图像的图像的部分。

    Measurement device and measurement method
    4.
    发明授权
    Measurement device and measurement method 有权
    测量装置及测量方法

    公开(公告)号：US08896311B2

    公开(公告)日：2014-11-25

    申请号：US13258743

    申请日：2010-03-25

    申请人： Hideo Utsumi ,  Kazuhiro Ichikawa ,  Tetsuhiko Takahashi

    发明人： Hideo Utsumi ,  Kazuhiro Ichikawa ,  Tetsuhiko Takahashi

    IPC分类号： G01V3/00 ,  A61B5/055 ,  G01R33/563 ,  G01R33/60 ,  G01R33/48 ,  G01R33/565 ,  G01R33/38 ,  G01R33/44

    CPC分类号： G01R33/4808 ,  A61B5/055 ,  A61B5/0555 ,  G01R33/3806 ,  G01R33/445 ,  G01R33/56383 ,  G01R33/56509 ,  G01R33/60

    摘要： A measuring instrument and a measurement method which measures, using magnetic resonance, images such as a functional image, a morphologic image of an object to be measured eliminate the influences of the moving speed of the object to be measured during moving, thereby obtaining a precise measured image. The instrument comprises: the first and second external magnetic field generation devices which generate magnetic fields for exciting the magnetic resonance of a mouse (M) as a living body to be measured; a turntable which rotates and moves the mouse (M) as an object to be measured, thereby moving the mouse (M) in the magnetic fields of the first and second external magnetic field generation devices; an OMRI measurement processing unit and an MRI measurement processing unit which obtain measured image signals within the mouse (M) by phase encoding while applying a gradient magnetic field in the moving direction (y) of the mouse (M) without stopping during the movement by the turntable; and a measured signal correction unit which corrects the measured image signal (S (k., ky)), thereby obtaining a corrected image signal (S′ (k., ky)) wherein influence of movement in y-direction is corrected.

    摘要翻译： 使用磁共振测量功能图像，待测量对象的形态图像的测量仪器和测量方法消除了移动期间被测量物体的移动速度的影响，从而获得精确的 测量图像。 仪器包括：第一和第二外部磁场产生装置，其产生用于激发作为要测量的活体的鼠标（M）的磁共振的磁场; 旋转并移动作为测量对象的鼠标（M）的转台，从而在第一和第二外部磁场产生装置的磁场中移动鼠标（M）; OMRI测量处理单元和MRI测量处理单元，其通过相位编码获得鼠标（M）内的测量图像信号，同时在移动期间不停止地在鼠标（M）的移动方向（y）上施加梯度磁场， 转盘; 以及校正测量图像信号（S（k，ky））的测量信号校正单元，从而获得校正了在y方向上的移动影响的校正图像信号（S'（k，ky））。

    Measurement device and measurement method
    5.
    发明授权
    Measurement device and measurement method 有权
    测量装置及测量方法

    公开(公告)号：US08532740B2

    公开(公告)日：2013-09-10

    申请号：US13002920

    申请日：2009-07-07

    申请人： Kazuhiro Ichikawa ,  Hideo Utsumi

    发明人： Kazuhiro Ichikawa ,  Hideo Utsumi

    IPC分类号： A61B5/05

    CPC分类号： A61B5/0555 ,  A61B5/0035 ,  A61B2503/40 ,  G01N24/10 ,  G01R33/3806 ,  G01R33/381 ,  G01R33/3815 ,  G01R33/383 ,  G01R33/481 ,  G01R33/4812 ,  G01R33/56375 ,  G01R33/56383 ,  G01R33/60 ,  G01R33/62

    摘要： A measurement device and measurement method make it possible to eliminate the load generated by stopping on a measurement subject that is moved among multiple magnetic field generating devices. The measurement device includes a first external magnetic field generating device that generates a magnetic field of a set size, a second external magnetic field generating device that generates a magnetic field of a size that differs from that of the magnetic field of the first external magnetic field generating device, a rotating table that causes the subject of measurement to pass in sequence through the magnetic fields of the first and second external magnetic field generating devices by causing the subject of measurement to move rotationally, and an OMRI measurement processing part and MRI measurement processing part that measures images such as functional images or structural images of the subject of measurement while it is being moved rotationally by the rotating table.

    摘要翻译： 测量装置和测量方法可以消除由在多个磁场产生装置之间移动的测量对象停止而产生的负载。 测量装置包括产生一定尺寸的磁场的第一外部磁场产生装置，产生尺寸与第一外部磁场的磁场的磁场不同的磁场的第二外部磁场产生装置 生成装置，通过使测量对象旋转移动使得测量对象依次通过第一外部磁场产生装置和第二外部磁场产生装置的磁场的旋转台，以及OMRI测量处理部分和MRI测量处理 在通过旋转台旋转移动的同时测量诸如测量对象的功能图像或结构图像的图像的部分。

    MEASUREMENT DEVICE AND MEASUREMENT METHOD
    6.
    发明申请
    MEASUREMENT DEVICE AND MEASUREMENT METHOD 有权
    测量装置和测量方法

    公开(公告)号：US20120068705A1

    公开(公告)日：2012-03-22

    申请号：US13258743

    申请日：2010-03-25

    申请人： Hideo Utsumi ,  Kazuhiro Ichikawa ,  Tetsuhiko Takahashi

    发明人： Hideo Utsumi ,  Kazuhiro Ichikawa ,  Tetsuhiko Takahashi

    IPC分类号： G01R33/56

    CPC分类号： G01R33/4808 ,  A61B5/055 ,  A61B5/0555 ,  G01R33/3806 ,  G01R33/445 ,  G01R33/56383 ,  G01R33/56509 ,  G01R33/60

    摘要： A measuring instrument and a measurement method which measures, using magnetic resonance, images such as a functional image, a morphologic image of an object to be measured eliminate the influences of the moving speed of the object to be measured during moving, thereby obtaining a precise measured image. The instrument comprises: the first and second external magnetic field generation devices which generate magnetic fields for exciting the magnetic resonance of a mouse (M) as a living body to be measured; a turntable which rotates and moves the mouse (M) as an object to be measured, thereby moving the mouse (M) in the magnetic fields of the first and second external magnetic field generation devices; an OMRI measurement processing unit and an MRI measurement processing unit which obtain measured image signals within the mouse (M) by phase encoding while applying a gradient magnetic field in the moving direction (y) of the mouse (M) without stopping during the movement by the turntable; and a measured signal correction unit which corrects the measured image signal (S (k., ky)), thereby obtaining a corrected image signal (S′ (k., ky)) wherein influence of movement in y-direction is corrected.

    摘要翻译： 使用磁共振测量功能图像，待测量对象的形态图像的测量仪器和测量方法消除了移动期间被测量物体的移动速度的影响，从而获得精确的 测量图像。 仪器包括：第一和第二外部磁场产生装置，其产生用于激发作为要测量的活体的鼠标（M）的磁共振的磁场; 旋转并移动作为测量对象的鼠标（M）的转台，从而在第一和第二外部磁场产生装置的磁场中移动鼠标（M）; OMRI测量处理单元和MRI测量处理单元，其通过相位编码获得鼠标（M）内的测量图像信号，同时在移动期间不停止地在鼠标（M）的移动方向（y）上施加梯度磁场， 转盘; 以及校正测量图像信号（S（k，ky））的测量信号校正单元，从而获得校正了在y方向上的移动影响的校正图像信号（S'（k，ky））。

    Printer, printer setting method and corresponding program, and cartridge
    7.
    发明授权
    Printer, printer setting method and corresponding program, and cartridge 失效
    打印机，打印机设置方法和相应的程序以及墨盒

    公开(公告)号：US07324232B2

    公开(公告)日：2008-01-29

    申请号：US10443144

    申请日：2003-05-22

    申请人： Osamu Ishibashi ,  Kazuhiro Ichikawa

    发明人： Osamu Ishibashi ,  Kazuhiro Ichikawa

    IPC分类号： G06K15/02

    CPC分类号： G06F3/1205 ,  G06F3/1204 ,  G06F3/1229 ,  G06F3/1257 ,  G06F3/1284

    摘要： A color laser printer 10 compares a pervious printer, which a toner cartridge 40 has been attached to immediately before attachment to the current printer, with the current printer. In the case where the previous printer is different from the current printer, the color laser printer 10 obtains setting information on the previous printer, which is stored in a storage element 50 of the toner cartridge 40, and applies the obtained setting information for the current printer. The various settings in the previous printer are thus turned over to the current printer, when the toner cartridge 40 is detached from the previous printer and is attached to the current printer. This arrangement ensures smooth printing operations without requiring any troublesome settings to use the current printer.

    摘要翻译： 彩色激光打印机10将当前打印机附着之前已经安装了调色剂盒40的透光打印机与当前打印机进行比较。 在前一打印机与当前打印机不同的情况下，彩色激光打印机10获取存储在调色剂盒40的存储元件50中的先前打印机的设置信息，并将获得的当前设置信息 打印机。 因此，当墨粉盒40与先前的打印机分离并且附接到当前的打印机时，上一个打印机中的各种设置因此被翻转到当前的打印机。 这种布置确保平滑的打印操作，而不需要使用当前打印机的任何麻烦的设置。

    Image formation device and recording agent cartridge attached thereto
    8.
    发明申请
    Image formation device and recording agent cartridge attached thereto 有权
    图像形成装置和附着于其上的记录剂盒

    公开(公告)号：US20050123310A1

    公开(公告)日：2005-06-09

    申请号：US10797564

    申请日：2004-03-11

    申请人： Osamu Ishibashi ,  Kazuhiro Ichikawa

    发明人： Osamu Ishibashi ,  Kazuhiro Ichikawa

    IPC分类号： G03G21/00 ,  G03G15/00 ,  G03G15/01 ,  G03G15/08

    CPC分类号： G03G15/553 ,  G03G15/556 ,  G03G2221/163 ,  G03G2221/1823

    摘要： Toner cartridges 32C, 32M, 32Y, and 32K have storage elements 33C, 33M, 33Y, and 33K mounted thereon to transmit information carried on electromagnetic wave in a predetermined frequency band. An information receiver transmitter unit 30 is located in a neighborhood of an end of a developer unit 23 with the toner cartridges 32C, 32M, 32Y, and 32K attached thereto to transmit information carried on the electromagnetic wave in the predetermined frequency band to and from a color laser printer 20. While the developer unit 23 is rotated to develop each color component image with a supply of toner from the corresponding one of the toner cartridges 32C, 32M, 32Y, and 32K, the information receiver transmitter unit 30 is controlled to write a cumulative toner consumption and a cumulative number of printed sheets into the corresponding one of the storage elements 33C, 33M, 33Y, and 33K.

    摘要翻译： 调色剂盒32C，32M，32Y和32K具有安装在其上的存储元件33C，33M，33Y和33K，以在预定频带中传送在电磁波上承载的信息。 信息接收器发送器单元30位于显影单元23的端部附近，附带有调色剂盒32C，32M，32Y和32K，以便在预定频带内传送电磁波上携带的信息 来自彩色激光打印机20。 当显影单元23旋转以通过从相应的一个调色剂盒32C，32M，32Y和32K供应调色剂来显影每个颜色分量图像时，控制信息接收器发送器单元30写入 累积调色剂消耗量和累积打印片数到存储元件33C，33M，33Y和33K中相应的一个。