公开(公告)号：US09757357B2

公开(公告)日：2017-09-12

申请号：US14113877

申请日：2012-04-27

申请人： Hideya Yuasa ,  Shun-ichiro Ogura ,  Kiwamu Takahashi ,  Katushi Inoue ,  Tohru Tanaka

发明人： Hideya Yuasa ,  Shun-ichiro Ogura ,  Kiwamu Takahashi ,  Katushi Inoue ,  Tohru Tanaka

IPC分类号： A61K31/409 ,  A61K41/00 ,  A61K49/00 ,  A61K31/197

CPC分类号： A61K31/409 ,  A61K31/197 ,  A61K41/0061 ,  A61K41/0071 ,  A61K49/0019 ,  A61K49/0021 ,  A61K49/0052 ,  A61K49/0093

摘要： It is intended to provide a therapeutic and/or diagnostic agent that can be used in photodynamic therapy (PDT) or photodynamic diagnosis (PDD) capable of utilizing infrared-spectrum light such as near-infrared light (NIR), infrared light, or far-infrared light, which attains a deep body penetration. The present invention provides a photodynamic therapeutic or diagnostic agent or a photodynamic therapeutic or diagnostic kit for cancer or infectious disease, comprising: a particle (e.g., a lanthanide particle) that emits upconversion luminescence by infrared-spectrum light such as near-infrared light having a wavelength of 0.7 μm to 2.5 μm; and a photosensitizer (e.g., porphyrin) or a 5-aminolevulinic acid group.

公开(公告)号：US20140056817A1

公开(公告)日：2014-02-27

申请号：US14113877

申请日：2012-04-27

申请人： Hideya Yuasa ,  Shun-ichiro Ogura ,  Kiwamu Takahashi ,  Katushi Inoue ,  Tohru Tanaka

发明人： Hideya Yuasa ,  Shun-ichiro Ogura ,  Kiwamu Takahashi ,  Katushi Inoue ,  Tohru Tanaka

IPC分类号： A61K31/409 ,  A61K49/00 ,  A61K31/197

CPC分类号： A61K31/409 ,  A61K31/197 ,  A61K41/0061 ,  A61K41/0071 ,  A61K49/0019 ,  A61K49/0021 ,  A61K49/0052 ,  A61K49/0093

摘要： It is intended to provide a therapeutic and/or diagnostic agent that can be used in photodynamic therapy (PDT) or photodynamic diagnosis (PDD) capable of utilizing infrared-spectrum light such as near-infrared light (NIR), infrared light, or far-infrared light, which attains a deep body penetration. The present invention provides a photodynamic therapeutic or diagnostic agent or a photodynamic therapeutic or diagnostic kit for cancer or infectious disease, comprising: a particle (e.g., a lanthanide particle) that emits upconversion luminescence by infrared-spectrum light such as near-infrared light having a wavelength of 0.7 μm to 2.5 μm; and a photosensitizer (e.g., porphyrin) or a 5-aminolevulinic acid group.

摘要翻译： 旨在提供可用于能够利用红外光谱（例如近红外光（NIR），红外光或远）的光动力学治疗（PDT）或光动力学诊断（PDD）的治疗和/或诊断剂 - 红外光，其深度穿透力。 本发明提供了一种用于癌症或感染性疾病的光动力学治疗或诊断剂或光动力学治疗或诊断试剂盒，其包括：通过红外光谱如近红外光发射上转换发光的颗粒（例如镧系元素颗粒），其具有 波长0.7μm至2.5μm; 和光敏剂（例如卟啉）或5-氨基乙酰丙酸基团。