公开(公告)号：US20090318814A1

公开(公告)日：2009-12-24

申请号：US12096178

申请日：2006-12-01

申请人： Hirohiko Kuratsune ,  Akikazu Sakudo ,  Kazuyoshi Ikuta ,  Yasuyoshi Watanabe ,  Yoshiki Nishizawa ,  Yukiyoshi Hirase ,  Seiki Tajima ,  Yoshikazu Suganuma

发明人： Hirohiko Kuratsune ,  Akikazu Sakudo ,  Kazuyoshi Ikuta ,  Yasuyoshi Watanabe ,  Yoshiki Nishizawa ,  Yukiyoshi Hirase ,  Seiki Tajima ,  Yoshikazu Suganuma

IPC分类号： A61B6/00

CPC分类号： A61B5/0059 ,  G01N21/35 ,  G01N21/359

摘要： The present invention is a method and an apparatus for examination/diagnosis of lifestyle related disease, wherein the test sample from a human or other animal subject is irradiated with light having a wavelength region of a region of 400 nm-2,500 nm or a part of the region, of which the reflection light, the transmission light, or the transmission reflection light is then detected to give spectroscopic data of absorbance, and afterward a previously prepared analysis model is used to execute an analysis of the absorbance at the whole or specific wavelength used for the measurement.

摘要翻译： 本发明是一种用于生活方式相关疾病的检查/诊断的方法和装置，其中来自人或其他动物受试者的测试样品用波长区域为400nm-2500nm的光或部分 然后检测其中反射光，透射光或透射反射光的区域，以得到吸光度的光谱数据，然后使用预先制备的分析模型来执行整个或特定波长处的吸光度的分析 用于测量。

公开(公告)号：US20110028808A1

公开(公告)日：2011-02-03

申请号：US12307263

申请日：2008-12-31

申请人： Hirohiko Kuratsune ,  Akikazu Sakudo ,  Junzo Nojima ,  Kazuyoshi Ikuta ,  Yasuyoshi Watanabe ,  Yukiko Kato ,  Takanori Kobayashi ,  Seiki Tajima

发明人： Hirohiko Kuratsune ,  Akikazu Sakudo ,  Junzo Nojima ,  Kazuyoshi Ikuta ,  Yasuyoshi Watanabe ,  Yukiko Kato ,  Takanori Kobayashi ,  Seiki Tajima

IPC分类号： A61B6/00 ,  G01J5/02

CPC分类号： A61B5/0059 ,  A61B2562/0238 ,  G01N21/359 ,  G01N21/474

摘要： An object of the present invention is to provide apparatuses for examining/diagnosing clinical disease of cancer, systemic lupus erythematosus (SLE), or antiphospholipid antibody syndrome. Blood, blood-derived component, urine, sweat, nail, skin, or hair is irradiated with light having a wavelength of 400 to 2,500 nm or a part of the range, of which the reflection light, the transmission light, or the transmission reflection light is then detected to give spectroscopic absorbance data, and afterward a previously prepared analysis model is used to analyze the absorbance over the whole wavelengths or at a specific wavelength for the measurement to allow the achievement of the object.

摘要翻译： 本发明的目的是提供用于检查/诊断癌症，系统性红斑狼疮（SLE）或抗磷脂抗体综合征的临床疾病的装置。 用波长为400〜2500nm的光或其范围的一部分照射血液，血液成分，尿液，汗液，指甲，皮肤或毛发，其中反射光，透射光或透射反射 然后检测光以得到光谱吸收数据，然后使用预先制备的分析模型来分析整个波长或特定波长处的吸光度用于测量以允许实现该目的。

公开(公告)号：US20130210045A1

公开(公告)日：2013-08-15

申请号：US13805449

申请日：2011-08-22

申请人： Yosky Kataoka ,  Guanghua Jin ,  Yasuyoshi Watanabe ,  Seiki Tajima ,  Tomoyoshi Soga ,  Hirohiko Kuratsune ,  Emi Yamano

发明人： Yosky Kataoka ,  Guanghua Jin ,  Yasuyoshi Watanabe ,  Seiki Tajima ,  Tomoyoshi Soga ,  Hirohiko Kuratsune ,  Emi Yamano

IPC分类号： C12Q1/54 ,  C12Q1/34 ,  C12Q1/527 ,  C12Q1/32 ,  C12Q1/48 ,  C12Q1/52

CPC分类号： C12Q1/54 ,  C12Q1/32 ,  C12Q1/34 ,  C12Q1/485 ,  C12Q1/52 ,  C12Q1/527 ,  G01N33/50 ,  G01N2570/00 ,  G01N2800/306

摘要： Ratios of measured values of glucose, citrate, and cis-aconitate in a biological sample obtained from a subject to measured values of glucose, citrate, and cis-aconitate in a biological sample obtained from a healthy subject are calculated, and the glucose ratio, the citrate ratio, and the cis-aconitate ratio are used to evaluate and/or assess fatigue. Similarly, an isocitrate ratio, a succinate ratio, a malate ratio, and a lactate ratio are calculated, and these ratios are used together with the three ratios to evaluate and/or assess fatigue. This makes it possible to objectively and easily diagnose and evaluate fatigue.

摘要翻译： 计算从受试者获得的生物样品中的葡萄糖，柠檬酸盐和顺式乌头酸的测量值与从健康受试者获得的生物样品中的葡萄糖，柠檬酸盐和顺式乌头酸的测量值的比例， 柠檬酸盐比例和顺式乌头酸比率用于评估和/或评估疲劳。 类似地，计算异柠檬酸酯比例，琥珀酸酯比例，苹果酸酯比例和乳酸盐比例，并且将这些比率与三种比率一起使用以评估和/或评估疲劳。 这使得客观，轻松地诊断和评估疲劳成为可能。