公开(公告)号：US5725370A

公开(公告)日：1998-03-10

申请号：US581203

申请日：1995-12-29

申请人： Hiroshi Himeno ,  Kazuko Himeno ,  Kenichi Kita ,  Tadashi Imanishi

发明人： Hiroshi Himeno ,  Kazuko Himeno ,  Kenichi Kita ,  Tadashi Imanishi

IPC分类号： F02D45/00 ,  A61C3/03 ,  F02D29/04 ,  F02D41/14 ,  F02D41/16 ,  A61C1/07

CPC分类号： A61C3/03

摘要： A dental tip comprises a proximal end portion connected to a drive source and a distal end portion adapted to act on a region to be subjected to dental treatment. The distal and proximal end portions are formed of a composite-material molded product which includes a plastic base material and an inorganic filler or/and an organic filler compounded therewith. This tip can produce the same treatment effect as a conventional one without damaging teeth or prostheses in dental treatment, and can be manufactured with ease. Thus, the tip is low-priced and disposable.

摘要翻译： 牙尖包括连接到驱动源的近端部分和适于作用于经受牙齿治疗的区域的远端部分。 远端部分和近端部分由复合材料模制产品形成，该复合材料模制产品包括塑料基材和无机填料或/和与其混合的有机填料。 该尖端可以产生与常规的一样的治疗效果，而不会在牙齿治疗中损伤牙齿或假体，并且可以容易地制造。 因此，尖端是低价和一次性的。

公开(公告)号：US20090137505A1

公开(公告)日：2009-05-28

申请号：US11992261

申请日：2006-09-20

申请人： Roberto Antonio Barrero ,  Takuro Tamura ,  Takashi Gojobori ,  Kazuho Ikeo ,  Tadashi Imanishi

发明人： Roberto Antonio Barrero ,  Takuro Tamura ,  Takashi Gojobori ,  Kazuho Ikeo ,  Tadashi Imanishi

IPC分类号： A61K31/7088 ,  G06F19/00 ,  G01N33/48 ,  C07H21/00

CPC分类号： C12Q1/6876 ,  C12N15/111 ,  C12N2310/14 ,  C12N2320/11 ,  C12N2330/10 ,  C12Q2600/158 ,  C12Q2600/178 ,  G16B15/00 ,  G16B20/00

摘要： It is intended to identify or estimate miRNAs and one or more target genes (target mRNAs) targeted thereby.A method of predicting or identifying miRNAs and one or more target mRNAs targeted thereby, which comprises calculating the most stable secondary structures of double-stranded RNAs, which can be formed by all partial sequences in all of the subject mRNAs with miRNAs, and the secondary structure energies thereof to thereby search for all partial sequences capable of having stable structures through the binding of miRNAs to mRNAs, and then calculating the most stable secondary structure, which can be formed by a subject partial sequence or regions in the vicinity of the subject partial sequence with partial sequences of the concerned mRNA, and the secondary structure energy thereof to thereby determine whether or not the subject partial sequence of the concerned mRNA has a structure capable of interacting with the miRNA.

摘要翻译： 旨在鉴定或估计miRNA和靶向靶基因的一个或多个靶基因（靶mRNA）。 一种预测或鉴定miRNA和由此靶向的一种或多种靶mRNA的方法，其包括计算双链RNA的最稳定的二级结构，其可以由所有与miRNA相关的所有受试者mRNA中的所有部分序列形成，并且次级 结构能量，从而通过miRNA与mRNA的结合搜索能够具有稳定结构的所有部分序列，然后计算最稳定的二级结构，其可以由受试者部分序列或受试者部分附近的区域形成 序列与相关mRNA的部分序列及其二级结构能，从而确定相关mRNA的受试者部分序列是否具有能够与miRNA相互作用的结构。