摘要:
In a vehicle diagnostic method and an external diagnostic device, sensor detection values acquired by communicating with an ECU are measured to determine whether the values are in a normal range while a vehicle is idling. After an engine is started, an operation to measure soundness is prohibited at least until the sensor detection values including the engine rotational frequency reach a threshold value region indicating the completion of the warm-up operation. The fluctuation state of the sensor detection values is displayed on an operation screen until the sensor detection values reach the threshold value region.
摘要:
In a vehicle diagnostic method and an external diagnostic device, sensor detection values acquired by communicating with an ECU are measured to determine whether the values are in a normal range while a vehicle is idling. After an engine is started, an operation to measure soundness is prohibited at least until the sensor detection values including the engine rotational frequency reach a threshold value region indicating the completion of the warm-up operation. The fluctuation state of the sensor detection values is displayed on an operation screen until the sensor detection values reach the threshold value region.
摘要:
In a vehicle diagnostic method and an external diagnostic device, the acceleration of a vehicle is detected while the vehicle is travelling with an acceleration detection means that is provided to the external diagnostic device mounted on the vehicle, and the external diagnostic device acquires operation information of the vehicle from the vehicle. The external diagnostic device performs at least one of a vehicle performance diagnosis, a driving technique diagnosis of the driver, and a fault diagnosis using the operation information and the acceleration of the vehicle.
摘要:
In a vehicle diagnostic method and an external diagnostic device, the acceleration of a vehicle is detected while the vehicle is travelling with an acceleration detection means that is provided to the external diagnostic device mounted on the vehicle, and the external diagnostic device acquires operation information of the vehicle from the vehicle. The external diagnostic device performs at least one of a vehicle performance diagnosis, a driving technique diagnosis of the driver, and a fault diagnosis using the operation information and the acceleration of the vehicle.
摘要:
The present invention provides 4-isopropylphenyl glucitol compounds which have no tendency to accumulate in the body and which inhibit SGLT1 activity to suppress postprandial hyperglycemia (or impaired glucose tolerance) through suppression of glucose absorption in the small intestine, whereby the compounds, for example, can suppress the onset of diabetes and metabolic syndrome or can treat these diseases.A 4-isopropylphenyl glucitol compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof: wherein R1 represents a hydrogen atom, etc., R2 represents a methyl group, etc., R3 represents a C1-4 alkyl group substituted with an amino group(s), etc., and R4 represents a hydrogen atom, etc.
摘要:
Provided is a novel C-phenyl glycitol compound that may serve as a prophylactic or therapeutic agent for diabetes by inhibiting both SGLT1 activity and SGLT2 activity, thereby exhibiting a glucose absorption suppression action and a urine glucose excretion action. A C-phenyl glycitol compound represented by Formula (I) below or a pharmaceutically acceptable salt thereof or a hydrate thereof wherein R1 and R2 are the same or different and represent a hydrogen atom, a hydroxyl group, a C1-6 alkyl group, a C1-6 alkoxy group or a halogen atom, R3 is a hydrogen atom, a C1-6 alkyl group, a C1-6 alkoxy group or a halogen atom, Y is a C1-6 alkylene group, —O—(CH2)n— (n is an integer of 1 to 4) or a C2-6 alkenylene group, provided that when Z is —NHC(═NH)NH2 or —NHCON(RB)RC, n is not 1, Z is —CONHRA, —NHC(═NH)NH2 or —NHCON(RB)RC,
摘要:
There is provided a 5-thio-β-D-glucopyranoside compound of the following formula, which has an inhibitory effect on SGLT2 activity, or a pharmaceutically acceptable salt thereof or a hydrate thereof. There is also provided a pharmaceutical preparation, particularly a prophylactic or therapeutic agent for diabetes, diabetes-related diseases or diabetic complications, which comprises such a compound as an active ingredient.
摘要:
A compound, which inhibits SGLT1 (sodium-dependent glucose transporter 1) activity to suppress absorption of glucose or the like, thereby suppressing abnormal glucose tolerance or postprandial hyperglycemia in diabetes, is provided. Specifically, a 4-isopropyl-6-methoxyphenyl glucitol compound represented by the following formula (I), or a pharmaceutically acceptable salt thereof, is provided:
摘要:
A 1-phenyl 1-thio-D-glucitol compound represented by formula (I) or the like: or a pharmaceutically acceptable salt thereof or a hydrate thereof, or a pharmaceutical preparation comprising the same as an active ingredient is useful as a novel type of prophylactic or therapeutic agent for diabetes, diabetes-related diseases or diabetic complications, which inhibits both SGLT1 and SGLT2 activities to achieve not only suppression of glucose absorption from the digestive tract but also excretion of urinary sugars.
摘要:
There is provided a heteroaryl 5-thio-β-D-glucopyranoside compound of the following formula, which has an inhibitory effect on SGLT2 activity, or a pharmaceutically acceptable salt thereof or a hydrate thereof. There is also provided a pharmaceutical preparation, particularly a prophylactic or therapeutic agent for diabetes, diabetes-related diseases or diabetic complications, which comprises such a compound as an active ingredient.