公开(公告)号：US11879904B2

公开(公告)日：2024-01-23

申请号：US17507874

申请日：2021-10-22

Applicant: Roche Diagnostics Operations, Inc. ,  Hitachi High-Technologies Corporation

Inventor： Kouhei Nonaka ,  Takamichi Mori ,  Yoichi Aruga ,  Yosuke Horie ,  Andrew McCaughey ,  Alexander Seiler

IPC: G01N35/10 ,  B01L3/02 ,  G01N35/00 ,  B01F31/00

CPC classification number: G01N35/1004 ,  G01N35/1009 ,  B01F31/00 ,  B01L3/0275 ,  G01N2035/00524 ,  G01N2035/00554

Abstract: A method of washing an aspiration probe of an in-vitro diagnostic system is disclosed. The aspiration probe comprises an outer surface and an inner surface forming an inner space for receiving a fluid. The method comprises dipping the aspiration probe into a first wash fluid so that the outer surface is immersed at least in part into the first wash fluid, aspirating an amount of the first wash fluid into the inner space of the aspiration probe, propagating an ultrasonic vibration to the outer surface of the aspiration probe via the first wash fluid, and rinsing the outer surface and the inner surface of the aspiration probe with a second wash fluid. Further, an in-vitro diagnostic method and an in-vitro diagnostic system are disclosed.

公开(公告)号：US11175301B2

公开(公告)日：2021-11-16

申请号：US15752616

申请日：2016-08-23

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION ,  ROCHE DIAGNOSTICS OPERATIONS, INC.

Inventor： Takamichi Mori ,  Kouhei Nonaka ,  Masaki Hara ,  Masato Ishizawa ,  Hitoshi Tokieda ,  Stephan Sattler

IPC: G01N35/10 ,  G01N35/00 ,  G01N35/04

Abstract: An automatic analyzer includes: a reagent mounting unit 103 in which a plurality of reagent bottles 10 are installed when a reagent bottle 10 is loaded into the automatic analyzer; a reagent conveying mechanism 101 including a gripper mechanism 106; and a reagent mounting mechanism 102 for moving the reagent mounting unit 103 between an installation position at which an operator installs the reagent bottle 10 in the reagent mounting unit 103 and a position at which the gripper mechanism 106 grips the reagent bottle 10. It is thereby possible to achieve saving of a mechanism installation space and reduction of the number of constituent components, automatically carry out an operation from opening of the reagent bottle to loading of the reagent bottle into the reagent disk, and alleviate an operator's burden.

公开(公告)号：US20220113331A1

公开(公告)日：2022-04-14

申请号：US17507874

申请日：2021-10-22

Applicant: Roche Diagnostics Operations, Inc. ,  Hitachi High-Technologies Corporation

Inventor： Kouhei Nonaka ,  Takamichi Mori ,  Yoichi Aruga ,  Yosuke Horie ,  Andrew McCaughey ,  Alexander Seiler

IPC: G01N35/10

Abstract: A method of washing an aspiration probe of an in-vitro diagnostic system is disclosed. The aspiration probe comprises an outer surface and an inner surface forming an inner space for receiving a fluid. The method comprises dipping the aspiration probe into a first wash fluid so that the outer surface is immersed at least in part into the first wash fluid, aspirating an amount of the first wash fluid into the inner space of the aspiration probe, propagating an ultrasonic vibration to the outer surface of the aspiration probe via the first wash fluid, and rinsing the outer surface and the inner surface of the aspiration probe with a second wash fluid. Further, an in-vitro diagnostic method and an in-vitro diagnostic system are disclosed.

公开(公告)号：US10786835B2

公开(公告)日：2020-09-29

申请号：US15580910

申请日：2016-06-27

Applicant: Hitachi High-Technologies Corporation

Inventor： Yosuke Horie ,  Tomohiro Inoue ,  Takamichi Mori ,  Kouhei Nonaka ,  Masato Ishizawa ,  Isao Yamazaki ,  Hitoshi Tokieda ,  Akihiro Nojima

IPC: B08B3/12 ,  B08B3/14 ,  G01N1/14 ,  G01N35/10

Abstract: An ultrasonic cleaner according to the present invention includes a vibrating part 222 for enlarging ultrasonic vibration of a BLT 100 on a side surface side in a cleaning tank 211, generates cavitation by the ultrasonic vibration with respect to cleaning liquid supplied into the cleaning tank 211 by driving the BLT 100 on the periphery of a nozzle without unevenness, and is capable of performing effective nozzle cleaning.

公开(公告)号：US10768193B2

公开(公告)日：2020-09-08

申请号：US15747446

申请日：2016-07-13

Applicant: Hitachi High-Technologies Corporation

Inventor： Masaru Miyazaki ,  Takamichi Mori ,  Kouhei Nonaka

IPC: G01N35/10 ,  G01N35/00 ,  G01N35/02 ,  B01L3/00 ,  G01N35/04

Abstract: A needle for forming a cut in a reagent bottle lid is shaped such that an expansion portion which pushes and opens a cut and a piercing portion which forms the cut are integrated with each other. Consequently, only a single operation for moving the needle downwardly will form a cut using the needle and expand the cut using the expansion portion. Further, the smaller diameter of the expansion portion than the diameter of a circumscribed circle of a cross section of the piercing portion but equal to or greater than the diameter of the reagent probe can form cuts uniformly.