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公开(公告)号：US20190382480A1
公开(公告)日：2019-12-19
申请号：US16269413
申请日：2019-02-06
发明人： Valeria Lifke , Guy Georges , Victor Levitsky , Oliver Ploettner , Stefan Seeber , Barbara Weiser , Ildiko Wuensche , Adrian Zwick
摘要： The invention provides anti-TIM3 antibodies and methods of using the same.
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公开(公告)号：US20220363755A1
公开(公告)日：2022-11-17
申请号：US17645272
申请日：2021-12-20
发明人： Valeria Lifke , Guy Georges , Victor Levitsky , Oliver Ploettner , Stefan Seeber , Barbara Weiser , Ildiko Wuensche , Adrian Zwick
摘要： The invention provides anti-TIM3 antibodies and methods of using the same.
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公开(公告)号：US10287352B2
公开(公告)日：2019-05-14
申请号：US15280372
申请日：2016-09-29
发明人： Laura Codarri-Deak , Georg Fertig , Jens Fischer , Christian Klein , Viktor Levitski , Valeria Lifke , Mario Perro , Joerg Thomas Regula , Tilman Schlothauer , Stefan Seeber , Pablo Umana , Ildiko Wuensche , Adrian Zwick
摘要： The invention relates to bispecific antibodies comprising a first antigen-binding site that specifically binds to PD1 and a second antigen-binding site that specifically binds to TIM3, in particular to bispecific antibodies, wherein the bispecific antibody binds to TIM3 with a lower binding affinity when compared to the binding to PD1. The invention further relates to methods of producing these molecules and to methods of using the same.
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公开(公告)号：US20180072804A1
公开(公告)日：2018-03-15
申请号：US15493559
申请日：2017-04-21
发明人： Valeria Lifke , Guy Georges , Victor Levitsky , Oliver Ploettner , Stefan Seeber , Barbara Weiser , Ildiko Wuensche , Adrian Zwick
IPC分类号： C07K16/28
摘要： The invention provides anti-TIM3 antibodies and methods of using the same.
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公开(公告)号：US20170247454A1
公开(公告)日：2017-08-31
申请号：US15280810
申请日：2016-09-29
发明人： Joerg Benz , Laura Codarri Deak , Stefan Dengl , Sebastian Fenn , Jens Fischer , Guy Georges , Christian Klein , Viktor Levitski , Valeria Lifke , Oliver Ploettner , Stefan Seeber , Barbara Weiser , Ildiko Wuensche , Adrian Zwick
IPC分类号： C07K16/28
CPC分类号： C07K16/2818 , A61K2039/505 , C07K2317/24 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/76 , C07K2317/92
摘要： The present invention relates to anti-PD1 antibodies and methods of using the same.
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公开(公告)号：US11130810B2
公开(公告)日：2021-09-28
申请号：US16367017
申请日：2019-03-27
发明人： Laura Codarri-Deak , Georg Fertig , Jens Fischer , Christian Klein , Viktor Levitski , Valeria Lifke , Mario Perro , Joerg Thomas Regula , Tilman Schlothauer , Stefan Seeber , Pablo Umana , Ildiko Wuensche , Adrian Zwick
摘要： The invention relates to bispecific antibodies comprising a first antigen-binding site that specifically binds to PD1 and a second antigen-binding site that specifically binds to TIM3, in particular to bispecific antibodies, wherein the bispecific antibody binds to 5 TIM3 with a lower binding affinity when compared to the binding to PD1. The invention further relates to methods of producing these molecules and to methods of using the same.
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公开(公告)号：US20160257749A1
公开(公告)日：2016-09-08
申请号：US14935309
申请日：2015-11-06
发明人： Valeria Lifke , Guy Georges , Victor Levitsky , Oliver Ploettner , Stefan Seeber , Barbara Weiser , Ildiko Wuensche , Adrian Zwick
摘要： The invention provides anti-TIM3 antibodies and methods of using the same.
摘要翻译： 本发明提供抗TIM3抗体及其使用方法。
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