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公开(公告)号：US09693997B2
公开(公告)日：2017-07-04
申请号：US14768915
申请日：2014-03-03
发明人： Joseph Anthony Bilotta , Zhi Chen , Feng Chi , Elbert Chin , Qingjie Ding , Shawn David Erickson , Stephen Deems Gabriel , Nan Jiang , Buelent Kocer , Eric Mertz , Jean-Marc Plancher , Robert J. Weikert , Jing Zhang , Qiang Zhang
IPC分类号： C07D249/14 , C07D401/12 , C07D403/12 , C07D405/12 , C07D417/12 , C07D491/107 , C07D495/04 , A61K31/4196 , A61K31/454 , A61K31/428 , A61K31/496 , A61K31/5377 , A61K31/538 , A61K31/541 , A61K31/5415 , A61K45/06 , C07D411/12 , C07D413/12
CPC分类号： A61K31/4196 , A61K31/428 , A61K31/454 , A61K31/496 , A61K31/5377 , A61K31/538 , A61K31/541 , A61K31/5415 , A61K45/06 , C07D249/14 , C07D401/12 , C07D403/12 , C07D405/12 , C07D411/12 , C07D413/12 , C07D417/12 , C07D491/107 , C07D495/04
摘要： The present invention discloses compounds of Formula I: wherein the variables in Formula I are defined as described herein. Also disclosed are pharmaceutical compositions containing such compounds and methods for using the compounds of Formula I in the prevention or treatment of HCV infection.
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公开(公告)号：US20170081312A1
公开(公告)日：2017-03-23
申请号：US15370568
申请日：2016-12-06
发明人： Steven Joseph Berthel , Zhi Chen , Feng Chi , Elbert Chin , David Shawn Erickson , Stephen Deems Gabriel , Buelent Kocer , Eric Mertz , Jean-Marc Plancher , Robert J. Weikert
IPC分类号： C07D401/12 , A61K38/21 , A61K31/4439 , C07D403/12 , A61K31/506 , C07D409/12 , A61K31/4196 , A61K31/501 , C07D471/04 , A61K31/437 , A61K31/496 , A61K45/06 , C07D487/10
CPC分类号： C07D401/12 , A61K31/4196 , A61K31/437 , A61K31/4439 , A61K31/496 , A61K31/501 , A61K31/506 , A61K38/21 , A61K45/06 , C07D249/14 , C07D403/12 , C07D409/12 , C07D471/04 , C07D487/10
摘要： The present invention discloses compounds of Formula (I): wherein the variables in Formula (I) are defined as described herein. Also disclosed are pharmaceutical compositions containing such compounds and methods for using the compounds of Formula (I) in the prevention or treatment of HCV infection.
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公开(公告)号：US20150368228A1
公开(公告)日：2015-12-24
申请号：US14766905
申请日：2014-03-03
发明人： Steven Joseph Berthel , Zhi Chen , Feng Chi , Elbert Chin , David Shawn Erickson , Stephen Deems Gabriel , Buelent Kocer , Eric Mertz , Jean-Marc Plancher , Robert J. Weikert
IPC分类号： C07D401/12 , C07D403/12 , A61K31/506 , C07D487/10 , A61K31/4196 , A61K38/21 , C07D471/04 , A61K31/437 , C07D249/14 , A61K31/496 , C07D409/12 , A61K45/06 , A61K31/4439 , A61K31/501
CPC分类号： C07D401/12 , A61K31/4196 , A61K31/437 , A61K31/4439 , A61K31/496 , A61K31/501 , A61K31/506 , A61K38/21 , A61K45/06 , C07D249/14 , C07D403/12 , C07D409/12 , C07D471/04 , C07D487/10
摘要： The present invention discloses compounds of Formula (I): wherein the variables in Formula (I) are defined as described herein. Also disclosed are pharmaceutical compositions containing such compounds and methods for using the compounds of Formula (I) in the prevention or treatment of HCV infection.
摘要翻译： 本发明公开了式（I）的化合物：其中式（I）中的变量如本文所述定义。 还公开了含有这些化合物的药物组合物和使用式（I）化合物在预防或治疗HCV感染中的方法。
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公开(公告)号：US20160000760A1
公开(公告)日：2016-01-07
申请号：US14768915
申请日：2014-03-03
发明人： Joseph Anthony Bilotta , Zhi Chen , Feng Chi , Elbert Chin , Qingjie Ding , Shawn David Erickson , Stephen Deems Gabriel , Nan Jiang , Buelent Kocer , Eric Mertz , Jean-Marc Plancher , Robert J. Weikert , Jing Zhang , Qiang Zhang
IPC分类号： A61K31/4196 , A61K31/454 , A61K45/06 , C07D403/12 , C07D249/14 , C07D417/12 , A61K31/428 , A61K31/496 , A61K31/5377 , C07D495/04 , C07D413/12 , A61K31/538 , A61K31/541 , A61K31/5415 , C07D405/12 , C07D491/107 , C07D401/12
CPC分类号： A61K31/4196 , A61K31/428 , A61K31/454 , A61K31/496 , A61K31/5377 , A61K31/538 , A61K31/541 , A61K31/5415 , A61K45/06 , C07D249/14 , C07D401/12 , C07D403/12 , C07D405/12 , C07D411/12 , C07D413/12 , C07D417/12 , C07D491/107 , C07D495/04
摘要： The present invention discloses compounds of Formula I: wherein the variables in Formula I are defined as described herein. Also disclosed are pharmaceutical compositions containing such compounds and methods for using the compounds of Formula I in the prevention or treatment of HCV infection.
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公开(公告)号：US09540345B2
公开(公告)日：2017-01-10
申请号：US14766905
申请日：2014-03-03
发明人： Steven Joseph Berthel , Zhi Chen , Feng Chi , Elbert Chin , David Shawn Erickson , Stephen Deems Gabriel , Buelent Kocer , Eric Mertz , Jean-Marc Plancher , Robert J. Weikert
IPC分类号： C07D401/12 , C07D403/12 , C07D487/10 , C07D471/04 , C07D409/12 , C07D249/14 , A61K31/4196 , A61K31/437 , A61K31/496 , A61K31/501 , A61K31/4439 , A61K31/506 , A61K38/21 , A61K45/06
CPC分类号： C07D401/12 , A61K31/4196 , A61K31/437 , A61K31/4439 , A61K31/496 , A61K31/501 , A61K31/506 , A61K38/21 , A61K45/06 , C07D249/14 , C07D403/12 , C07D409/12 , C07D471/04 , C07D487/10
摘要： The present invention discloses compounds of Formula (I): wherein the variables in Formula (I) are defined as described herein. Also disclosed are pharmaceutical compositions containing such compounds and methods for using the compounds of Formula (I) in the prevention or treatment of HCV infection.
摘要翻译： 本发明公开了式（I）的化合物：其中式（I）中的变量如本文所述定义。 还公开了含有这些化合物的药物组合物和使用式（I）化合物在预防或治疗HCV感染中的方法。
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公开(公告)号：US20160002180A1
公开(公告)日：2016-01-07
申请号：US14768619
申请日：2014-03-03
发明人： Qingjie Ding , Nan Jiang , Robert J. Weikert
IPC分类号： C07D249/14 , C07D401/12 , A61K38/21 , A61K31/5377 , A61K45/06 , A61K31/4196 , A61K31/4439
CPC分类号： C07D249/14 , A61K31/4196 , A61K31/4439 , A61K31/5377 , A61K38/21 , A61K45/06 , C07D401/12
摘要： The present invention discloses compounds of Formula (I) wherein the variables in Formula (I) are defined as described herein. Also disclosed are pharmaceutical compositions containing such compounds and methods for using the compounds of Formula (I) in the prevention or treatment of HCV infection.
摘要翻译： 本发明公开了式（I）的化合物，其中式（I）中的变量如本文所述定义。 还公开了含有这些化合物的药物组合物和使用式（I）化合物在预防或治疗HCV感染中的方法。
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公开(公告)号：US20140010783A1
公开(公告)日：2014-01-09
申请号：US13933468
申请日：2013-07-02
发明人： Joseph A. Bilotta , Zhi Chen , Elbert Chin , Qingjie Ding , Shawn D. Erickson , Stephen D. Gabriel , Klaus G. Klumpp , Han Ma , Eric Mertz , Jean-Marc Plancher , Robert J. Weikert
IPC分类号： C07D249/14 , A61K38/21 , A61K31/5377 , C07D403/12 , A61K31/4196 , A61K45/06
CPC分类号： C07D249/14 , A61K31/4196 , A61K31/5377 , A61K38/21 , A61K38/55 , A61K45/06 , C07D403/12 , A61K2300/00
摘要： The present invention discloses compounds of Formula I: wherein the variables in Formula I are defined as described herein. Also disclosed are pharmaceutical compositions containing such compounds and methods for using the compounds of Formula I in the prevention or treatment of HCV infection.
摘要翻译： 本发明公开了式I的化合物：其中式I中的变量如本文所述定义。 还公开了含有这些化合物的药物组合物和使用式I化合物预防或治疗HCV感染的方法。
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