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公开(公告)号:US20070216661A1
公开(公告)日:2007-09-20
申请号:US11640945
申请日:2006-12-19
申请人: Hsi-Kun Chen , Ching-Shih Chen , Yi-Shen Wang , John C. Wang , Hsing-Chiang Huang , Ming-San Huang
发明人: Hsi-Kun Chen , Ching-Shih Chen , Yi-Shen Wang , John C. Wang , Hsing-Chiang Huang , Ming-San Huang
IPC分类号: G06F3/041
CPC分类号: G06F3/0485 , G06F3/038
摘要: Information navigation methods. Contact is made with a touch-sensitive surface, and a navigation speed is determined according to contact movement speed. Information is continuously navigated according to the navigation speed.
摘要翻译: 信息导航方法。 接触触摸感应表面,并根据接触移动速度确定导航速度。 信息根据导航速度不断导航。
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公开(公告)号:US07669289B2
公开(公告)日:2010-03-02
申请号:US11470665
申请日:2006-09-07
申请人: Chin-Chung Shih , Yi-Shen Wang , Ching-Shih Chen , Yun-Long Tun , Ming-San Huang , John C. Wang
发明人: Chin-Chung Shih , Yi-Shen Wang , Ching-Shih Chen , Yun-Long Tun , Ming-San Huang , John C. Wang
IPC分类号: E05D3/10
CPC分类号: E05D11/0081 , E05D3/10 , E05Y2900/606 , G06F1/1616 , G06F1/1681 , H04M1/0222 , Y10T16/547 , Y10T16/5472 , Y10T16/557
摘要: A dual-axis hinge includes at least a connecting section, an upper hinge and a lower hinge. The connecting section has two sides orthogonally connected to the upper and lower hinges respectively. The connecting section has a circuit cavity that communicates with circuit outlets of the upper and lower hinges to form a passage for accommodating a transmission circuit. The upper hinge is connected to a first sleeve for joining the top cover of a folding electronic product, and the lower hinge is connected to a second sleeve for joining the body of the folding electronic product. These connections enable the top cover to rotate in at least two different directions.
摘要翻译: 双轴铰链至少包括连接部分,上铰链和下铰链。 连接部分具有分别与上铰链和下铰链正交连接的两个侧面。 连接部分具有与上部和下部铰链的电路出口连通以形成用于容纳传输电路的通道的电路腔。 上铰链连接到用于连接折叠电子产品的顶盖的第一套筒,并且下铰链连接到用于连接折叠电子产品的主体的第二套筒。 这些连接使得顶盖能够在至少两个不同的方向上旋转。
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3.
公开(公告)号:US07595980B2
公开(公告)日:2009-09-29
申请号:US11538110
申请日:2006-10-03
申请人: John C. Wang , Ching-Shih Chen , Chin-Chung Shih , Yun-Long Tun , Yi-Shen Wang , Ming-San Huang
发明人: John C. Wang , Ching-Shih Chen , Chin-Chung Shih , Yun-Long Tun , Yi-Shen Wang , Ming-San Huang
CPC分类号: H04M1/0222 , Y10T16/5472
摘要: A multi-configuration portable electronic device including a first body, a second body, a dual-axis hinge and at least a guiding module is provided. The dual-axis hinge has a first axis pivotally coupled to the first body and a second axis pivotally coupled to the second body. The guiding module prevents the first axis and the second axis from acting simultaneously. The guiding module includes a track disposed in the first body and a slide connected with the second body. The slide has an interaction force with the track so that the slide can move from the second body to couple with the track.
摘要翻译: 提供了包括第一主体,第二主体,双轴铰链和至少一个引导模块的多配置便携式电子设备。 双轴铰链具有枢转地联接到第一主体的第一轴线和可枢转地联接到第二主体的第二轴线。 引导模块防止第一轴和第二轴同时作用。 引导模块包括设置在第一主体中的轨道和与第二主体连接的滑块。 滑块具有与轨道的相互作用力,使得滑块可以从第二主体移动以与轨道耦合。
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公开(公告)号:US07573728B2
公开(公告)日:2009-08-11
申请号:US11555456
申请日:2006-11-01
申请人: Ching-Shih Chen , Chin-Chung Shih , Yun-Long Tun , Ming-San Huang , Yi-Shen Wang , John C. Wang
发明人: Ching-Shih Chen , Chin-Chung Shih , Yun-Long Tun , Ming-San Huang , Yi-Shen Wang , John C. Wang
IPC分类号: H04B1/03
CPC分类号: H05K1/028 , H01R35/025
摘要: A dual-axis circuit board is disclosed. The circuit board includes at least an upper circuit board, a lower circuit board, and a connecting circuit board. The upper circuit board connects to the circuit in a top cover of the folding electronic apparatus, and the lower circuit board connects to the circuit in the body of the folding electronic apparatus. The angle between the folding directions of the upper and lower circuit board is approximately 90 degrees.
摘要翻译: 公开了一种双轴电路板。 电路板至少包括上电路板,下电路板和连接电路板。 上电路板连接到折叠电子设备的顶盖中的电路,下电路板连接到折叠电子设备的主体中的电路。 上下电路板的折叠方向之间的角度约为90度。
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5.
公开(公告)号:US20070121303A1
公开(公告)日:2007-05-31
申请号:US11538110
申请日:2006-10-03
申请人: John Wang , Ching-Shih Chen , Chin-Chung Shih , Yun-Long Tun , Yi-Shen Wang , Ming-San Huang
发明人: John Wang , Ching-Shih Chen , Chin-Chung Shih , Yun-Long Tun , Yi-Shen Wang , Ming-San Huang
IPC分类号: H05K5/00
CPC分类号: H04M1/0222 , Y10T16/5472
摘要: A multi-configuration portable electronic device including a first body, a second body, a dual-axis hinge and at least a guiding module is provided. The dual-axis hinge has a first axis pivotally coupled to the first body and a second axis pivotally coupled to the second body. The guiding module prevents the first axis and the second axis from acting simultaneously. The guiding module includes a track disposed in the first body and a slide connected with the second body. The slide has an interaction force with the track so that the slide can move from the second body to couple with the track.
摘要翻译: 提供了包括第一主体,第二主体,双轴铰链和至少一个引导模块的多配置便携式电子设备。 双轴铰链具有枢转地联接到第一主体的第一轴线和可枢转地联接到第二主体的第二轴线。 引导模块防止第一轴和第二轴同时作用。 引导模块包括设置在第一主体中的轨道和与第二主体连接的滑块。 滑块具有与轨道的相互作用力,使得滑块可以从第二主体移动以与轨道耦合。
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公开(公告)号:US09079899B2
公开(公告)日:2015-07-14
申请号:US13882897
申请日:2011-10-31
申请人: Ching-Shih Chen , Hao-Chieh Chiu , Dasheng Wang , Samuel K. Kulp
发明人: Ching-Shih Chen , Hao-Chieh Chiu , Dasheng Wang , Samuel K. Kulp
IPC分类号: A61K31/415 , A61K31/5415 , C07D471/04 , C07D231/12 , C07D405/04
CPC分类号: C07D471/04 , A61K31/415 , A61K31/5415 , C07D231/12 , C07D405/04
摘要: A method of treating infection by Staphylococcus in a subject by administering a pharmaceutical composition including a celecoxib derivative of formula I or a pharmaceutically acceptable salt thereof is described. The preparation of numerous celecoxib derivatives for testing as potential anti-staphylococcal agents is also described.
摘要翻译: 描述了通过施用包含式I的塞来昔布衍生物或其药学上可接受的盐的药物组合物来治疗受试者中葡萄球菌感染的方法。 还描述了用于测试作为潜在的抗葡萄球菌剂的众多塞来昔布衍生物的制备。
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公开(公告)号:US20140364477A1
公开(公告)日:2014-12-11
申请号:US14468408
申请日:2014-08-26
申请人: Ching-Shih Chen , Jing-Ping Liou , Hsing-Jin Liu , Kuo-Sheng Hung , Pei-Wen Shan , Wen-Ta Chiu , Che-Ming Teng
发明人: Ching-Shih Chen , Jing-Ping Liou , Hsing-Jin Liu , Kuo-Sheng Hung , Pei-Wen Shan , Wen-Ta Chiu , Che-Ming Teng
IPC分类号: C07D209/08 , C07D209/30 , C07D209/18
CPC分类号: C07D209/08 , C07D209/12 , C07D209/18 , C07D209/30 , C07D209/40
摘要: Indolyl or indolinyl compounds of formula (I): wherein bond, n, R1, R2, R3, R4, R5, and R6, are defined herein. Also disclosed is a method for treating cancer with these compounds.
摘要翻译: 式(I)的吲哚基或二氢吲哚基化合物:其中键,n,R 1,R 2,R 3,R 4,R 5和R 6在本文中定义。 还公开了用这些化合物治疗癌症的方法。
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公开(公告)号:US20140031388A1
公开(公告)日:2014-01-30
申请号:US13952032
申请日:2013-07-26
申请人: Ching-Shih Chen , Dasheng Wang , Samuel K. Kulp
发明人: Ching-Shih Chen , Dasheng Wang , Samuel K. Kulp
IPC分类号: C07D311/60 , C07D405/10 , C07D493/10 , C07D215/20 , C07D327/08
CPC分类号: C07D311/60 , C07D215/20 , C07D311/72 , C07D327/06 , C07D327/08 , C07D405/10 , C07D493/10
摘要: Anticancer compounds according to formula I are described herein. wherein R1, R2, R3 and R4 are selected from H, CH3, OH, SH, OCH3, NHR′, halogen, CF3, N-linked pyrrolidine, and SO2NHR′, or any combination thereof; R5 is an alkyl, alkenyl, or alkaryl group including from 4 to 11 carbons, X is selected from CH2, CHOH, C═O, S═O, O═S═O, and an oxetane ring, Y is selected from CH2, O, and NH, and R′ is a H, aryl, or a lower alkyl group, or pharmaceutically acceptable salts thereof. The compounds have been shown to facilitate site-specific dephosphorylation of Akt at Ser-473, thereby inactivating Akt and decreasing dysregulation of Akt signaling that can occur in cancer cells.
摘要翻译: 本文描述了根据式I的抗癌化合物。 其中R1,R2,R3和R4选自H,CH3,OH,SH,OCH3,NHR',卤素,CF3,N-连接的吡咯烷和SO2NHR'或其任意组合; R5是包含4至11个碳的烷基,烯基或烷芳基,X选自CH 2,CHOH,C = O,S = O,O = S = O,氧杂环丁烷环,Y选自CH 2, O和NH,R'是H,芳基或低级烷基,或其药学上可接受的盐。 已经显示这些化合物促进Ser-473处的Akt的位点特异性去磷酸化,从而使Akt失活并减少可能发生在癌细胞中的Akt信号传导的调节异常。
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公开(公告)号:US08580827B2
公开(公告)日:2013-11-12
申请号:US13610967
申请日:2012-09-12
IPC分类号: A61K31/41
CPC分类号: C07D231/12
摘要: A series of celecoxib derivatives defined by Formula I: were prepared and evaluated for their ability to inhibit the gram-negative bacteria Francisella tularensis. Pharmaceutical compositions including celecoxib derivatives and their use in methods for treating or preventing infection by Francisella tularensis in a subject are described.
摘要翻译: 制备由式I定义的一系列塞来昔布衍生物,并评价其抑制革兰氏阴性细菌弗兰西斯拉氏弧菌的能力。 描述了包括塞来昔布衍生物的药物组合物及其在治疗或预防受试者中的弗朗西斯氏菌感染的方法中的用途。
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公开(公告)号:US08546397B2
公开(公告)日:2013-10-01
申请号:US13329593
申请日:2011-12-19
申请人: Ching-Shih Chen , Arthur Y. Shaw , Yu-Wei Leu , Shu-Huei Hsiao
发明人: Ching-Shih Chen , Arthur Y. Shaw , Yu-Wei Leu , Shu-Huei Hsiao
IPC分类号: A61K31/497
CPC分类号: G01N33/57415 , A61K31/121 , A61K31/352 , A61K31/416 , A61K31/495 , G01N33/57419 , G01N33/57423 , G01N33/57434 , G01N2500/00
摘要: A number of DNA methylation inhibitors are described. The DNA methylation inhibitors were identified using a two-component enhanced green fluorescent protein reporter system to screen a compound library containing procainamide derivatives. The DNA methylation inhibitors can be used for cancer therapy and prevention.
摘要翻译: 描述了许多DNA甲基化抑制剂。 使用双组分增强的绿色荧光蛋白报道系统鉴定DNA甲基化抑制剂以筛选含有普鲁卡因酰胺衍生物的化合物文库。 DNA甲基化抑制剂可用于癌症治疗和预防。
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