Dna chip based genetic typing
    2.
    发明申请
    Dna chip based genetic typing 有权
    基于Dna芯片的遗传分型

    公开(公告)号:US20070134661A1

    公开(公告)日:2007-06-14

    申请号:US10562803

    申请日:2003-07-18

    IPC分类号: C12Q1/68 C12M3/00

    CPC分类号: C12Q1/6837

    摘要: This invention relates generally to the field of nucleic acid analysis. In particular, the invention provides a method for typing a target gene, using, inter alia, a chip comprising a support suitable for use in nucleic acid hybridization having immobilized thereon an oligonucleotide probe complementary to said target nucleotide sequence and at least one of the following oligonucleotide control probes: a positive control probe, a negative control probe, a hybridization control probe and an immobilization control probe. Oligonucleotide probes or probes arrays for typing a HLA target gene are also provided.

    摘要翻译: 本发明一般涉及核酸分析领域。 特别地,本发明提供了一种用于对目标基因进行分型的方法,特别地,使用包含适合用于核酸杂交的载体的芯片,其上固定有与所述靶核苷酸序列互补的寡核苷酸探针和至少一种以下 寡核苷酸对照探针:阳性对照探针,阴性对照探针,杂交对照探针和固定化对照探针。 还提供了用于分型HLA靶基因的寡核苷酸探针或探针阵列。