-
1.3-(4-AMIDOPYRROL-2-YLMETHYLIDENE)-2-INDOLINONE DERIVATIVES AS PROTEIN KINASE INHIBITORS 失效
标题翻译: 作为蛋白激酶抑制剂的3-(4-氨基吡咯-2-基甲基)-2-吲哚啉酮衍生物公开(公告)号:US20080045709A1
公开(公告)日:2008-02-21
申请号:US11779807
申请日:2007-07-18
申请人: Huiping Guan , Congxin Liang , Li Sun , Peng Cho Tang , Chung Wei , Tomas Vojkovsky , Qingwu Jin , Paul Herrinton , Michael Mauragis
发明人: Huiping Guan , Congxin Liang , Li Sun , Peng Cho Tang , Chung Wei , Tomas Vojkovsky , Qingwu Jin , Paul Herrinton , Michael Mauragis
IPC分类号: C07D413/14
CPC分类号: C07D403/06 , C07D403/14 , C07D471/04
摘要: The present invention provides a method to make a pyrrole substituted 2-indolinone compound of the formula
摘要翻译: 本发明提供了制备下式的吡咯取代的2-二氢吲哚酮化合物的方法
-
2.
公开(公告)号:US20070027149A1
公开(公告)日:2007-02-01
申请号:US11511981
申请日:2006-08-28
申请人: Huiping Guan , Congxin Liang , Connie Sun , Peng Cho Tang , Chung Chen Wei , Tomas Vojkovsky , Qingwu Jin , Paul Herrinton , Michael Mauragis
发明人: Huiping Guan , Congxin Liang , Connie Sun , Peng Cho Tang , Chung Chen Wei , Tomas Vojkovsky , Qingwu Jin , Paul Herrinton , Michael Mauragis
IPC分类号: A61K31/5377 , A61K31/4192 , A61K31/405 , C07D403/14 , C07D413/14
CPC分类号: C07D403/06 , C07D403/14 , C07D471/04
摘要: The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.
-