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    E.Coli Mutant Containing Mutant Genes Related with Tryptophan Biosynthesis and Production Method of Tryptophan by Using the Same
    5.
    发明申请
    E.Coli Mutant Containing Mutant Genes Related with Tryptophan Biosynthesis and Production Method of Tryptophan by Using the Same 有权
    含有色氨酸生物合成突变基因的大肠杆菌突变体及其使用色氨酸的生产方法

    公开(公告)号：US20080299644A1

    公开(公告)日：2008-12-04

    申请号：US10582196

    申请日：2004-11-23

    申请人： Young-Hoon Park ,  Sang-jo Lim ,  Byoung-Hoon Kim ,  Seong-Jun Kim ,  Ho-Soo Lim

    发明人： Young-Hoon Park ,  Sang-jo Lim ,  Byoung-Hoon Kim ,  Seong-Jun Kim ,  Ho-Soo Lim

    IPC分类号： C12N1/21

    CPC分类号： C07K14/245 ,  C12N9/88 ,  C12P13/227

    摘要： The present invention relates to a Tryptophan-producing E. coli mutant strain CJ285 (KCCM-10534) containing single or multi mutant genes related with Tryptophan biosynthesis and production method of Tryptophan using the same. More particularly, DNA base sequences and amino acid sequences aroF, aroG, trpR, and tyrR originated from tryptophan producing E. coli mutant strain CJ285 (KCCM-10534) and related with Tryptophan biosynthesis, are disclosed, and E. coli CJ285 containing at least one of the mutant genes is cultivated directly in a glucose-containing fermentation medium, whereby L-tryptophan can be accumulated in the culture medium.

    摘要翻译： 本发明涉及含有与色氨酸生物合成相关的单个或多个突变基因的色氨酸产生大肠杆菌突变菌株CJ285（KCCM-10534）和使用其的色氨酸生产方法。 更具体地，公开了源自产生色氨酸的大肠杆菌突变菌株CJ285（KCCM-10534）并与色氨酸生物合成相关的DNA碱基序列和氨基酸序列aroF，aroG，trpR和tyrR，并且至少含有至少含有 其中一个突变基因直接在含葡萄糖的发酵培养基中培养，从而可以将L-色氨酸堆积在培养基中。

    E.coli mutant containing mutant genes related with tryptophan biosynthesis and production method of tryptophan by using the same
    6.
    发明授权
    E.coli mutant containing mutant genes related with tryptophan biosynthesis and production method of tryptophan by using the same 有权
    含有与色氨酸生物合成相关的突变基因的大肠杆菌突变体和使用其的色氨酸的生产方法

    公开(公告)号：US07638312B2

    公开(公告)日：2009-12-29

    申请号：US10582196

    申请日：2004-11-23

    申请人： Young-Hoon Park ,  Sang-jo Lim ,  Byoung-Hoon Kim ,  Seong-Jun Kim ,  Ho-Soo Lim

    发明人： Young-Hoon Park ,  Sang-jo Lim ,  Byoung-Hoon Kim ,  Seong-Jun Kim ,  Ho-Soo Lim

    IPC分类号： C12P13/22 ,  C12N9/00 ,  C12N1/20 ,  C07H21/04

    CPC分类号： C07K14/245 ,  C12N9/88 ,  C12P13/227

    摘要： The present invention relates to a Tryptophan-producing E. coli mutant strain CJ285 (KCCM-10534) containing single or multi mutant genes related with Tryptophan biosynthesis and production method of Tryptophan using the same. More particularly, DNA base sequences and amino acid sequences aroF, aroG, trpR, and tyrR originated from tryptophan producing E. coli mutant strain CJ285 (KCCM-10534) and related with Tryptophan biosynthesis, are disclosed, and E. coli CJ285 containing at least one of the mutant genes is cultivated directly in a glucose-containing fermentation medium, whereby L-tryptophan can be accumulated in the culture medium.

    摘要翻译： 本发明涉及含有与色氨酸生物合成相关的单个或多个突变基因的色氨酸产生大肠杆菌突变菌株CJ285（KCCM-10534）和使用其的色氨酸生产方法。 更具体地，公开了源自产生色氨酸的大肠杆菌突变菌株CJ285（KCCM-10534）并与色氨酸生物合成相关的DNA碱基序列和氨基酸序列aroF，aroG，trpR和tyrR，并且至少含有至少含有 其中一个突变基因直接在含葡萄糖的发酵培养基中培养，从而可以将L-色氨酸堆积在培养基中。