公开(公告)号：US20250010296A1

公开(公告)日：2025-01-09

申请号：US18572788

申请日：2023-03-24

Applicant: ILLUMINA, INC.

Inventor： Jack Twomey ,  Maulik Patel ,  Menggian Lu ,  Jay Taylor

IPC: B01L3/00

Abstract: Well assemblies and related systems and methods are disclosed. In accordance with an implementation, an apparatus includes a body having a first wall, a second wall, a cover, and an impermeable barrier. The first wall defines a well having a port and a distal end defining an opening having an opening perimeter. The second wall surrounds the first wall and has a distal end. The cover is coupled to the distal end of the first wall and covers the opening along the opening perimeter at a connected portion and uncoupled from the distal end of the first wall along the opening perimeter at an unconnected portion. The impermeable barrier is coupled to the distal end of the second wall and covers the well. The unconnected portion forms a vent that allows air flow out of the well.

公开(公告)号：US20240326042A1

公开(公告)日：2024-10-03

申请号：US18572786

申请日：2022-09-29

Applicant: ILLUMINA, INC.

Inventor： Bradley Drews ,  Darren Segale ,  Jennifer Foley ,  Jack Twomey

IPC: B01L3/00 ,  G01N15/1434

CPC classification number: B01L3/502715 ,  G01N15/1436 ,  B01L2200/026 ,  B01L2200/0689 ,  B01L2300/0887

Abstract: Flow cell manifold assemblies and methods are disclosed. In an implementation, an apparatus includes a flow cell and a flow cell manifold. The flow cell has a channel. The flow cell defines a plurality of first openings fluidically coupled to the channel and arranged on a first side of the channel and a plurality of second openings fluidically coupled the channel and arranged on a second side of the channel. The flow cell manifold assembly is coupled to the flow cell and has a first manifold fluidic line having a first fluidic line opening and being fluidically coupled to each of the first openings and has a second manifold fluidic line having a second fluidic line opening and being fluidically coupled to each of the second openings.