公开(公告)号：US20250010296A1

公开(公告)日：2025-01-09

申请号：US18572788

申请日：2023-03-24

Applicant: ILLUMINA, INC.

Inventor： Jack Twomey ,  Maulik Patel ,  Menggian Lu ,  Jay Taylor

IPC: B01L3/00

Abstract: Well assemblies and related systems and methods are disclosed. In accordance with an implementation, an apparatus includes a body having a first wall, a second wall, a cover, and an impermeable barrier. The first wall defines a well having a port and a distal end defining an opening having an opening perimeter. The second wall surrounds the first wall and has a distal end. The cover is coupled to the distal end of the first wall and covers the opening along the opening perimeter at a connected portion and uncoupled from the distal end of the first wall along the opening perimeter at an unconnected portion. The impermeable barrier is coupled to the distal end of the second wall and covers the well. The unconnected portion forms a vent that allows air flow out of the well.

公开(公告)号：US20240165627A1

公开(公告)日：2024-05-23

申请号：US18281018

申请日：2022-03-17

Applicant: ILLUMINA, INC.

Inventor： Mikko Ponkala ,  Paul Limb ,  Reto Schoch ,  Sonny Pham ,  Maulik Patel ,  Paul Crivelli

IPC: B01L3/00

CPC classification number: B01L3/527 ,  B01L2200/16 ,  B01L2300/0829 ,  B01L2300/18 ,  B01L2400/0487 ,  B01L2400/0638

Abstract: Non-contact dispenser assemblies and related systems and methods are disclosed. An implementation of an apparatus is disclosed that includes a reagent cartridge including a body defining a plurality of reservoirs. Each reservoir has an outlet and a distal end defining an opening, a manifold assembly including an outlet, a common fluidic line fluidly coupled to the outlet, a plurality of reagent fluidic lines coupled to the corresponding outlet of the reservoirs, and a plurality of membrane valves selectively fluidly coupling the common fluidic line and a corresponding one of the plurality of reagent fluidic lines.

公开(公告)号：US20230191405A1

公开(公告)日：2023-06-22

申请号：US18069688

申请日：2022-12-21

Applicant: ILLUMINA, INC.

Inventor： Zhenning Cao ,  Jennifer Foley ,  Cyril Delattre ,  Maulik Patel ,  Cameron Mar

IPC: B01L3/00 ,  G01F3/38

CPC classification number: B01L3/50273 ,  G01F3/38 ,  B01L2200/04 ,  B01L2200/16 ,  B01L2300/0627 ,  B01L2400/0487

Abstract: In some examples, an instrument for measuring a volume of a liquid is provided. A gas flow rate sensor may measure a rate of flow of a pressurized gas to a reservoir storing a liquid. A controller may be coupled to the gas flow rate sensor and may calculate a volume of the liquid that the flow of pressurized gas displaces from the reservoir. In some examples, a method of measuring a volume of a liquid is provided. Using a gas flow rate sensor, a flow of pressurized gas may be measured. The flow of the pressurized gas may be delivered to a reservoir storing a liquid. A volume of the liquid in the reservoir may be displaced using the flow of pressurized gas. The measurement of the flow of the pressurized gas may be used to calculate the volume of the liquid that is displaced.