公开(公告)号：US11311592B2

公开(公告)日：2022-04-26

申请号：US16799158

申请日：2020-02-24

Applicant: Academia Sinica ,  Industrial Technology Research Institute

Inventor： Chang-Jen Huang ,  Rita P.-Y. Chen ,  Yung-Feng Liao ,  Bo-Kai Wu ,  Po-Ting Chen ,  Hui-Ping Tsai ,  Yi-Cheng Cheng ,  Cheng-Li Fang ,  Hung-Chi Chien ,  Tien-Soung Tong ,  Ting-Shou Chen ,  Shu-Jiau Chiou

IPC: B01D11/02 ,  A61K36/48 ,  A61P25/28 ,  A61K9/00

Abstract: Disclosed herein is the novel use of use of a Bauhinia spp. extract, which may upregulate neprilysin, induce autophagy, protect neuron from amyloidopathy or tauopathy, and/or promote neurite outgrowth, thus the Bauhinia spp. extract of the present disclosure may be used as a dietary supplement for the prophylaxis or treatment of amyloid related neurodegenerative diseases so as to ameliorate or alleviate symptoms associated with the amyloid related neurodegenerative diseases.

公开(公告)号：US10821148B2

公开(公告)日：2020-11-03

申请号：US15416391

申请日：2017-01-26

Applicant: Industrial Technology Research Institute

Inventor： Kuo-Kuei Huang ,  I-Horng Pan ,  Ying-Fei Tsai ,  I-Huang Lu ,  Chu-Hsun Lu ,  Shu-Fang Wen ,  Zong-Keng Kuo ,  Shu-Jiau Chiou

IPC: A61K36/00 ,  A61K36/75 ,  A61K31/395 ,  A61K31/366 ,  A61K31/37 ,  A61K31/4015 ,  A61K31/404

Abstract: The present disclosure provides a pharmaceutical composition for treating or alleviating an autoimmune disease and/or complication thereof and/or nephritis, including: an effective amount of an extract of a plant belonging to Rutaceae as an effective ingredient for treating or alleviating the autoimmune disease and/or complication thereof and/or nephritis, wherein the autoimmune disease is selected from a group consisting of lupus erythematosus, psoriasis, psoriatic arthritis, ankylosing spondylitis, rheumatoid arthritis, juvenile idiopathic arthritis, Crohn's disease and ulcerative colitis (UC).

公开(公告)号：US09301944B2

公开(公告)日：2016-04-05

申请号：US13681397

申请日：2012-11-19

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Lain-Tze Lee ,  Shau-Feng Chang ,  Cheng Lin ,  Shao-Chan Yin ,  Shu-Jiau Chiou

IPC: A61K31/353 ,  A61K36/87 ,  A61K36/704

CPC classification number: A61K31/353 ,  A61K36/704 ,  A61K36/87 ,  A61K2300/00

Abstract: The disclosure provides a method for treating hepatitis C, including: administering an effective amount of a proanthocyanidins oligomer to a subject in need, wherein the structure of the proanthocyanidins oligomer is shown as Formula (I): and in Formula (I), N is an integer of about 1-18.

Abstract translation: 本发明提供一种治疗丙型肝炎的方法，包括：向有需要的受试者施用有效量的原花色素寡聚物，其中原花色素寡聚体的结构如式（I）所示：在式（I）中，N为 大约1-18的整数。