公开(公告)号：US20160008633A1

公开(公告)日：2016-01-14

申请号：US14771894

申请日：2014-03-06

申请人： Kobi VORTMAN ,  Shuki VITEK ,  Eyal ZADICARIO ,  INSIGHTEC, LTD.

发明人： Kobi Vortman ,  Shuki Vitek ,  Eyal Zadicario

IPC分类号： A61N7/00

CPC分类号： A61N7/00 ,  A61B2090/374 ,  A61N7/02 ,  A61N2007/0073 ,  A61N2007/0078

摘要： In ultrasound therapy, the frequency of sonications can be optimized, within a certain frequency range, to maximize the absorption or the acoustic intensity at the target in a manner specific to the patient.

摘要翻译： 在超声治疗中，可以在一定频率范围内优化声波的频率，以特定于患者的方式最大限度地增加靶上的吸收或声强。

公开(公告)号：US20230398381A1

公开(公告)日：2023-12-14

申请号：US18252133

申请日：2021-11-17

申请人： INSIGHTEC LTD.

发明人： Shuki Vitek ,  Kobi Vortman

IPC分类号： A61N7/02 ,  A61B90/00 ,  A61B34/10

CPC分类号： A61N7/02 ,  A61B90/37 ,  A61B34/10 ,  A61B2034/104 ,  A61N2007/0095

摘要： Focused-ultrasound systems and methods involve simultaneously determining multiple ultrasound parameters (e.g., applied acoustic power, frequency, phases, position, activation pattern, beam shape, wave shape, etc.) associated with the transducer array for generating optimal treatment effects both at the target region (e.g., causing a sufficient temperature increase for tissue necrosis to occur) and non-target region (e.g., having a clinically insignificant temperature increase to avoid damage to the non-target tissue). A computational model may simulate the treatment effects (e.g., the temperature, peak intensity, focus shape, location of the hot spot, etc.) of these ultrasound parameters on the target and/or non-target regions. Based on the simulation results, the computational model may simultaneously determine the optimal values of the multiple ultrasound parameters—i.e., the values that, while not necessarily optimal for each individual parameter considered in isolation, nonetheless produce optimal overall treatment effects at the target and non-target

公开(公告)号：US11806496B2

公开(公告)日：2023-11-07

申请号：US16771768

申请日：2018-12-05

申请人： INSIGHTEC, LTD.

发明人： Kobi Vortman ,  Yoav Levy ,  Oleg Prus ,  Shuki Vitek

IPC分类号： A61M37/00 ,  A61N7/00 ,  A61N7/02

CPC分类号： A61M37/0092 ,  A61N7/00 ,  A61N7/02 ,  A61M2205/50 ,  A61M2230/04 ,  A61M2230/205 ,  A61N2007/0004 ,  A61N2007/0039 ,  A61N2007/0052 ,  A61N2007/0056 ,  A61N2007/0073 ,  A61N2007/0078 ,  A61N2007/0095

摘要： Various approaches to focusing an ultrasound transducer includes causing the ultrasound transducer to transmit ultrasound waves to the target region; causing the detection system to indirectly measure the focusing properties; and based at least in part on the indirectly measured focusing properties, adjusting a parameter value associated with at least one of the transducer elements so as to achieve a target treatment power at the target region.