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35 条记录 (耗时 0.018 秒)

    Precedent-based ultrasound focusing
    1.
    发明授权
    Precedent-based ultrasound focusing 有权

    公开(公告)号：US11291430B2

    公开(公告)日：2022-04-05

    申请号：US16314808

    申请日：2017-07-14

    申请人： INSIGHTEC, LTD.

    发明人： Yoav Levy ,  Eyal Zadicario ,  Talia Amar

    IPC分类号： A61B8/08 ,  A61B6/00 ,  A61B8/00 ,  A61B90/00 ,  A61B6/03 ,  G06N3/02 ,  G06N20/00

    摘要： Various approaches for operating an ultrasound transducer having multiple transducer elements include acquiring one or more measurements of anatomical regions through which ultrasound waves emitted from the transducer elements travel; for each of the anatomical regions, determining values of characteristics based at least in part on the measurement(s); computationally predicting aberrations of the ultrasound waves traveling through the anatomical regions by using the first values as input to a predictor that has been computationally trained to predict ultrasound aberrations based on values of the characteristics; and driving the transducer elements to compensate for the predicted aberrations.

    Systems and methods for ensuring coherence between multiple ultrasound transducer arrays
    2.
    发明授权
    Systems and methods for ensuring coherence between multiple ultrasound transducer arrays 有权

    公开(公告)号：US11272842B2

    公开(公告)日：2022-03-15

    申请号：US16314092

    申请日：2017-06-20

    申请人： INSIGHTEC, LTD.

    发明人： Yoav Levy

    IPC分类号： A61B5/00 ,  A61N7/00 ,  A61B5/055 ,  A61B34/20 ,  G01R33/48 ,  A61B90/00 ,  A61B8/00 ,  G10K11/35

    摘要： A system for maintaining coherence of ultrasound waves emitted by multiple transducer arrays includes multiple retention arms, each for receiving one of the transducer arrays; a connecting frame for receiving and mechanically retaining the arms in fixed angular relation to each other; and a processor configured to determine relative locations of the transducer arrays with respect to one another and the connecting frame; determine a location of the connecting frame relative to an anatomic region of interest; determine a spatial arrangement of the transducer elements in each transducer array with respect to the anatomic region of interest; and adjust a transmission configuration of the transducer elements in the transducer arrays to achieve a desired focusing property with respect to the anatomic region of interest while maintaining coherence therebetween.

    ADAPTIVE, CLOSED-LOOP ULTRASOUND THERAPY
    3.
    发明申请
    ADAPTIVE, CLOSED-LOOP ULTRASOUND THERAPY 有权

    公开(公告)号：US20210170204A1

    公开(公告)日：2021-06-10

    申请号：US16771768

    申请日：2018-12-05

    申请人： INSIGHTEC, LTD.

    发明人： Kobi VORTMAN ,  Yoav LEVY ,  Oleg PRUS ,  Shuki VITEK

    IPC分类号： A61N7/00

    摘要： Various approaches to focusing an ultrasound transducer includes causing the ultrasound transducer to transmit ultrasound waves to the target region; causing the detection system to indirectly measure the focusing properties; and based at least in part on the indirectly measured focusing properties, adjusting a parameter value associated with at least one of the transducer elements so as to achieve a target treatment power at the target region.

    Focused ultrasound system with optimized monitoring of cavitation
    5.
    发明授权
    Focused ultrasound system with optimized monitoring of cavitation 有权

    公开(公告)号：US11872085B2

    公开(公告)日：2024-01-16

    申请号：US17057920

    申请日：2019-06-04

    申请人： INSIGHTEC, LTD.

    发明人： Kobi Vortman ,  Rafi De Picciotto

    IPC分类号： A61B8/00 ,  G01S15/89 ,  A61B90/00

    CPC分类号： A61B8/54 ,  A61B8/4488 ,  G01S15/8929 ,  A61B2090/374 ,  A61B2090/378

    摘要： Various approaches for generating an ultrasound focus at a target region and receiving signals therefrom using an ultrasound transducer having multiple transducer elements include acquiring multiple images of the target region and one or more path zones located on beam paths between the transducer elements and the target region; determining one or more tissue characteristics associated with the target region based on the acquired images; determining multiple profile parameters associated with each of the transducer elements based at least in part on the determined tissue characteristic; based at least in part on the profile parameters, operating at least first ones of the transducer elements to collectively transmit an ultrasound beam to the target region so as to create a focus thereon with desired properties; and based at least in part on the profile parameters, operating at least second ones of the transducer elements to receive acoustic signals from the target region and, in response thereto, adjusting operation of the at least first ones of the transducer elements to thereby improve the focus at the target region.

    MULTIPARAMETRIC OPTIMIZATION FOR ULTRASOUND PROCEDURES
    6.
    发明公开
    MULTIPARAMETRIC OPTIMIZATION FOR ULTRASOUND PROCEDURES 审中-公开

    公开(公告)号：US20230398381A1

    公开(公告)日：2023-12-14

    申请号：US18252133

    申请日：2021-11-17

    申请人： INSIGHTEC LTD.

    发明人： Shuki Vitek ,  Kobi Vortman

    IPC分类号： A61N7/02 ,  A61B90/00 ,  A61B34/10

    CPC分类号： A61N7/02 ,  A61B90/37 ,  A61B34/10 ,  A61B2034/104 ,  A61N2007/0095

    摘要： Focused-ultrasound systems and methods involve simultaneously determining multiple ultrasound parameters (e.g., applied acoustic power, frequency, phases, position, activation pattern, beam shape, wave shape, etc.) associated with the transducer array for generating optimal treatment effects both at the target region (e.g., causing a sufficient temperature increase for tissue necrosis to occur) and non-target region (e.g., having a clinically insignificant temperature increase to avoid damage to the non-target tissue). A computational model may simulate the treatment effects (e.g., the temperature, peak intensity, focus shape, location of the hot spot, etc.) of these ultrasound parameters on the target and/or non-target regions. Based on the simulation results, the computational model may simultaneously determine the optimal values of the multiple ultrasound parameters—i.e., the values that, while not necessarily optimal for each individual parameter considered in isolation, nonetheless produce optimal overall treatment effects at the target and non-target

    SYSTEMS AND METHODS FOR REDUCING INTERFERENCE BETWEEN MRI APPARATUS AND ULTRASOUND SYSTEMS
    8.
    发明申请
    SYSTEMS AND METHODS FOR REDUCING INTERFERENCE BETWEEN MRI APPARATUS AND ULTRASOUND SYSTEMS 有权

    公开(公告)号：US20230024998A1

    公开(公告)日：2023-01-26

    申请号：US17778364

    申请日：2020-12-11

    申请人： INSIGHTEC, LTD.

    发明人： Adi GREENBERG

    IPC分类号： G01R33/48 ,  A61B8/00 ,  G01S15/89

    摘要： Approaches for performing magnetic resonance (MR) imaging of an anatomic region in conjunction with an ultrasound operation on the anatomic region include transmitting multiple ultrasound waves or pulses having a fundamental frequency and multiple harmonics to the anatomic region; transmitting an MR pulse sequence to the anatomic region and receiving, therefrom, MR signals within a band of frequencies; and causing the band of frequencies to be located between two adjacent frequencies of the harmonics.

    CAVITATION-ENHANCED TARGETED DRUG DELIVERY AND DOSING
    10.
    发明申请
    CAVITATION-ENHANCED TARGETED DRUG DELIVERY AND DOSING 有权

    公开(公告)号：US20210146157A1

    公开(公告)日：2021-05-20

    申请号：US16622005

    申请日：2018-06-29

    申请人： INSIGHTEC, LTD.

    发明人： Yoav LEVY ,  Kobi VORTMAN

    IPC分类号： A61N5/10 ,  A61B5/00 ,  A61N7/02 ,  A61B34/10

    摘要： Various approaches for disrupting target tissue for treatment include identifying a target volume of the target tissue; causing disruption of the target tissue in a region corresponding to the target volume so as to increase tissue permeability therein; computationally generating a tissue permeability map of the target volume; and based on the tissue permeability map, computationally evaluating the disruption of the target tissue within the target volume.