公开(公告)号：US20180144098A1

公开(公告)日：2018-05-24

申请号：US15365961

申请日：2016-12-01

Applicant: INSTITUTE FOR INFORMATION INDUSTRY

Inventor： Wei-I LIU ,  Yu-Shian CHIU ,  Joey Jen-Hui SYU ,  Chia-Shan HSIEH ,  Mong-Hsun TSAI ,  Tzu-Pin LU ,  Liang-Chuan LAI ,  Eric Y. CHUANG ,  Hui-I HSIAO

IPC: G06F19/00 ,  G06F19/12

CPC classification number: G06F19/326 ,  G16B5/00 ,  G16B25/00 ,  G16H20/10 ,  G16H50/20

Abstract: A drug combination prediction method comprising: storing a plurality of original gene sets, at least one first gene impacted by a first drug and at least one second gene impacted by a second drug; determining the part of the at least one first gene and the part of the at least one second gene to be a first interaction gene set; calculating a gene amount of the first interaction gene set to obtain a first interaction gene amount, and calculating a first percentage generated by the first interaction gene amount in the first original gene set; calculating an interaction value of the combination of the first drug and the second drug according to the first percentage; and selecting at least one synergistic pharmaceutical composition according to the interaction value.