公开(公告)号：US20180144098A1

公开(公告)日：2018-05-24

申请号：US15365961

申请日：2016-12-01

Applicant: INSTITUTE FOR INFORMATION INDUSTRY

Inventor： Wei-I LIU ,  Yu-Shian CHIU ,  Joey Jen-Hui SYU ,  Chia-Shan HSIEH ,  Mong-Hsun TSAI ,  Tzu-Pin LU ,  Liang-Chuan LAI ,  Eric Y. CHUANG ,  Hui-I HSIAO

IPC: G06F19/00 ,  G06F19/12

CPC classification number: G06F19/326 ,  G16B5/00 ,  G16B25/00 ,  G16H20/10 ,  G16H50/20

Abstract: A drug combination prediction method comprising: storing a plurality of original gene sets, at least one first gene impacted by a first drug and at least one second gene impacted by a second drug; determining the part of the at least one first gene and the part of the at least one second gene to be a first interaction gene set; calculating a gene amount of the first interaction gene set to obtain a first interaction gene amount, and calculating a first percentage generated by the first interaction gene amount in the first original gene set; calculating an interaction value of the combination of the first drug and the second drug according to the first percentage; and selecting at least one synergistic pharmaceutical composition according to the interaction value.

公开(公告)号：US20170147744A1

公开(公告)日：2017-05-25

申请号：US14963196

申请日：2015-12-08

Applicant: INSTITUTE FOR INFORMATION INDUSTRY

Inventor： Chia-Yang CHENG ,  Joey Jen-Hui, SYU ,  Wei-I LIU ,  Mong-Hsun TSAI ,  Tzu-Pin LU ,  Liang-Chuan LAI ,  Eric-Y CHUANG

IPC: G06F19/22

CPC classification number: G16B30/00

Abstract: A system for analyzing sequencing data of bacterial strains and a method thereof are provided. The method for analyzing sequencing data of bacterial strains includes the following steps: searching a specific variable region of a first genetic sample sequence and searching another specific variable region of a second genetic sample sequence; determining whether both the specific variable region and the another specific variable region have an identical cross-sample subsequence; if both the specific variable region and the another specific variable region have the identical cross-sample subsequence, storing the cross-sample subsequence into a recording table; and if the identical cross-sample subsequence exists, comparing the cross-sample subsequence with a plurality of gene sequences of known strains stored in a database module to analyze a plurality of strains corresponding to the cross-sample subsequence in the first genetic sample sequence and the second genetic sample sequence.