公开(公告)号：US11111496B2

公开(公告)日：2021-09-07

申请号：US16481799

申请日：2018-01-30

Applicant: INTREXON CORPORATION

Inventor： Xinhua Zhao ,  Mark Anton Held ,  Tina Huynh ,  Lily Yuin Chao ,  Na Trinh ,  Matthias Helmut Schmalisch ,  Bryan Yeh ,  James Kealey ,  Kevin Lee Dietzel

IPC: C12N15/52 ,  C12N1/20 ,  C12N9/00 ,  C12N9/88 ,  C12N15/74 ,  C12P5/02 ,  C12P7/16 ,  C12P7/18 ,  C12N9/04 ,  C12N9/10

Abstract: Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as 2,3-BDO are disclosed. For example, genetically modified methanotrophs that are capable of generating 2,3-BDO at high titers from a methane source are disclosed. Methods of making these genetically modified microorganisms and methods of using them are also disclosed.