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公开(公告)号：US07670565B2
公开(公告)日：2010-03-02
申请号：US12074354
申请日：2008-03-03
IPC分类号： A61L2/20
CPC分类号： A61L2/208 , A61L2/24 , A61L9/015 , A61L2202/14 , A61L2202/25 , F24F3/16 , F24F2003/1664
摘要： When microbial contamination is introduced into a room (20*) of an enclosure, such as a building, an HVAC system including supply ductwork (16) and a return ductwork (34) is decontaminated with hydrogen peroxide vapor. A decontamination controller (46) operates controllable baffles (22) at outlet registers (20), temporary controllable baffles (44) at inlet registers (30), and a blower system (10) to circulate hydrogen peroxide vapor from hydrogen peroxide vapor generators (42) through the ductwork in both forward and reverse directions. Further, at least portions of the baffles are closed to create dwell times in which the hydrogen peroxide vapor resides in the ductwork with minimal or turbulent flow.
摘要翻译： 当将微生物污染物引入诸如建筑物的外壳的房间（20 *）中时，包括供应管道系统（16）和回流管道系统（34）的HVAC系统用过氧化氢蒸气去污。 净化控制器（46）在出口寄存器（20），入口寄存器（30）处的临时可控挡板（44）和用于使来自过氧化氢蒸汽发生器的过氧化氢蒸气循环的鼓风机系统（10）上操作可控挡板（22） 42）通过管道系统在正向和反向两个方向。 此外，挡板的至少一部分被关闭以产生停留时间，其中过氧化氢蒸汽驻留在具有最小或湍流的管道系统中。
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公开(公告)号：US20080152544A1
公开(公告)日：2008-06-26
申请号：US12074354
申请日：2008-03-03
CPC分类号： A61L2/208 , A61L2/24 , A61L9/015 , A61L2202/14 , A61L2202/25 , F24F3/16 , F24F2003/1664
摘要： When microbial contamination is introduced into a room (20*) of an enclosure, such as a building, an HVAC system including supply ductwork (16) and a return ductwork (34) is decontaminated with hydrogen peroxide vapor. A decontamination controller (46) operates controllable baffles (22) at outlet registers (20), temporary controllable baffles (44) at inlet registers (30), and a blower system (10) to circulate hydrogen peroxide vapor from hydrogen peroxide vapor generators (42) through the ductwork in both forward and reverse directions. Further, at least portions of the baffles are closed to create dwell times in which the hydrogen peroxide vapor resides in the ductwork with minimal or turbulent flow.
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公开(公告)号：US07361304B2
公开(公告)日：2008-04-22
申请号：US10767908
申请日：2004-01-29
IPC分类号： A61L2/20
CPC分类号： A61L2/208 , A61L2/24 , A61L9/015 , A61L2202/14 , A61L2202/25 , F24F3/16 , F24F2003/1664
摘要： When microbial contamination is introduced into a room (20*) of an enclosure, such as a building, an HVAC system including supply ductwork (16) and a return ductwork (34) is decontaminated with hydrogen peroxide vapor. A decontamination controller (46) operates controllable baffles (22) at outlet registers (20), temporary controllable baffles (44) at inlet registers (30), and a blower system (10) to circulate hydrogen peroxide vapor from hydrogen peroxide vapor generators (42) through the ductwork in both forward and reverse directions. Further, at least portions of the baffles are closed to create dwell times in which the hydrogen peroxide vapor resides in the ductwork with minimal or turbulent flow.
摘要翻译： 当将微生物污染物引入诸如建筑物的外壳的房间（20 *）中时，包括供应管道系统（16）和回流管道系统（34）的HVAC系统用过氧化氢蒸气去污。 净化控制器（46）在出口寄存器（20），入口寄存器（30）处的临时可控挡板（44）和用于使来自过氧化氢蒸汽发生器的过氧化氢蒸气循环的鼓风机系统（10）上操作可控挡板（22） 42）通过管道系统在正向和反向两个方向。 此外，挡板的至少一部分被关闭以产生停留时间，其中过氧化氢蒸汽驻留在具有最小或湍流的管道系统中。
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公开(公告)号：US07592500B2
公开(公告)日：2009-09-22
申请号：US10422474
申请日：2003-04-24
IPC分类号： A62D3/38
CPC分类号： A62D3/38 , A61L2/202 , A61L2/208 , A62D2101/02
摘要： An oxidizing liquid (20), such as hydrogen peroxide, is vaporized (18) and the vapor is used to deactivate nerve gas, blistering gas, or other biologically active substances such as pathogens, biotoxins, and prions. A second chemical compound (42) in vapor, mist, or fog form is used in conjunction with the oxidizing vapor. In one embodiment, the second chemical preconditions the biologically active substances to be deactivated more efficiently by the oxidizing vapor. In another embodiment, the second chemical boosts the reactivity of the oxidizing vapor. In another embodiment, the other chemical reacts with the oxidizing vapor to form an intermediate compound that deactivates at least some of the biologically active substances.
摘要翻译： 蒸发氧化液体（20）如过氧化氢（18），蒸汽用于使神经气体，起泡气体或其他生物活性物质如病原体，生物毒素和朊病毒失活。 蒸汽，雾或雾形式的第二化合物（42）与氧化蒸气结合使用。 在一个实施方案中，第二化学品通过氧化蒸气更有效地预先使待生物活性物质失活。 在另一个实施方案中，第二化学物质增强氧化蒸气的反应性。 在另一个实施方案中，其它化学物质与氧化蒸气反应形成中和化合物，其使至少一些生物活性物质失活。
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公开(公告)号：US08129579B2
公开(公告)日：2012-03-06
申请号：US12495849
申请日：2009-07-01
IPC分类号： A62D3/36
CPC分类号： A62D3/38 , A61L2/202 , A61L2/208 , A62D2101/02
摘要： An oxidizing liquid (20), such as hydrogen peroxide, is vaporized (18) and the vapor is used to deactivate nerve gas, blistering gas, or other biologically active substances such as pathogens, biotoxins, and prions. A second chemical compound (42) in vapor, mist, or fog form is used in conjunction with the oxidizing vapor. In one embodiment, the second chemical preconditions the biologically active substances to be deactivated more efficiently by the oxidizing vapor. In another embodiment, the second chemical boosts the reactivity of the oxidizing vapor. In another embodiment, the other chemical reacts with the oxidizing vapor to form an intermediate compound that deactivates at least some of the biologically active substances.
摘要翻译： 蒸发氧化液体（20）如过氧化氢（18），蒸汽用于使神经气体，起泡气体或其他生物活性物质如病原体，生物毒素和朊病毒失活。 蒸汽，雾或雾形式的第二化合物（42）与氧化蒸气结合使用。 在一个实施方案中，第二化学品通过氧化蒸气更有效地预先使待生物活性物质失活。 在另一个实施方案中，第二化学物质增强氧化蒸气的反应性。 在另一个实施方案中，其它化学物质与氧化蒸气反应形成中和化合物，其使至少一些生物活性物质失活。
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公开(公告)号：US07157046B2
公开(公告)日：2007-01-02
申请号：US10047317
申请日：2002-01-14
申请人： Iain F. McVey , Francis J. Zelina , Aaron L. Hill , Gerald E. McDonnell , Kevin O. Williams , Thaddeus Mielnik
发明人： Iain F. McVey , Francis J. Zelina , Aaron L. Hill , Gerald E. McDonnell , Kevin O. Williams , Thaddeus Mielnik
IPC分类号： A61L2/00
CPC分类号： A61L2/208 , A61L2202/11 , A61L2202/18 , A61L2202/23 , B65B55/025 , B65B55/10 , B67C7/0073
摘要： A flash vaporizer (34) provides a constant flow of vaporized hydrogen peroxide or other antimicrobial compounds for rapidly sterilizing large enclosures (10), such as rooms or buildings. The vaporizer includes a heated block (50) which defines an interior bore or bores (70, 72, 74). The flowpath created by the bore or bores increases in cross sectional area as the hydrogen peroxide passes through the block to accommodate the increase in volume during the conversion from liquid to gas. The vapor is injected into dry air in a duct that circulates it to the large enclosure.
摘要翻译： 闪蒸器（34）提供恒定的蒸发过氧化氢或其它抗微生物化合物的流动，用于快速消毒诸如房间或建筑物的大型封闭物（10）。 蒸发器包括限定内孔或孔（70,72,74）的加热块（50）。 由于孔或孔产生的流路的横截面积随着过氧化氢通过块而增加，以适应在从液体转化为气体期间的体积增加。 将蒸汽注入到将其循环到大外壳的管道中的干燥空气中。
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7.发明授权Vapor phase decontamination process biological indicator evaluator resistomer (BIER) vessel 有权气相去污过程生物指示剂评估仪（BIER）容器公开(公告)号：US06936434B2
公开(公告)日：2005-08-30
申请号：US10124384
申请日：2002-04-17
CPC分类号： A61L2/208 , A61L2/28 , A61L2202/122 , A61L2202/24 , C12Q1/22 , Y10S435/807
摘要： A BIER vessel evaluates biological indicators for sterilization processes. By flowing gaseous sterilant, such as vaporized hydrogen peroxide, through a chamber (12) before, during, and after introducing the indicators, the indicators are instantaneously exposed to preselected steady state conditions, allowing accurate and reproducible evaluation of the indicator response. A door (32) to an opening (30) in the chamber opens for introducing the indicators to the chamber without appreciably disturbing the steady state conditions therein. After a preselected time, the biological indicators are removed and evaluated for remaining biological activity.
摘要翻译： BIER容器评估灭菌过程的生物指标。 通过在引入指示剂之前，期间和之后，通过使气态灭菌剂（例如蒸发的过氧化氢）通过室（12），将指示剂瞬时暴露于预选的稳定状态条件下，允许对指示剂反应进行准确和可重复的评估。 在腔室中的开口（30）的门（32）打开，用于将指示器引导到腔室，而不会明显地干扰其中的稳态条件。 在预选时间之后，去除生物学指标并评估剩余生物活性。
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公开(公告)号：US07186374B2
公开(公告)日：2007-03-06
申请号：US10077224
申请日：2002-02-15
申请人： Francis J. Zelina , Gerald E. McDonnell , Aaron L. Hill , Thaddeus Mielnik , Iain F. McVey , Peter J. Buczynski
发明人： Francis J. Zelina , Gerald E. McDonnell , Aaron L. Hill , Thaddeus Mielnik , Iain F. McVey , Peter J. Buczynski
IPC分类号： A61L9/00
CPC分类号： A61L2/208 , A61L2/186 , A61L2202/23 , B65B55/025 , B65B55/10 , B67C7/0073
摘要： A flash vapor generator (10) provides a constant flow of vaporized hydrogen peroxide for rapidly sterilizing a large decontamination tunnel (11) with a high container throughput. The vaporizer includes a heated block which defines an interior bore or bores. The conditions within the decontamination tunnel are carefully monitored to avoid condensation of the vapor while maintaining the vapor as close as possible to the saturation limit.
摘要翻译： 闪蒸发生器（10）提供恒定的气化过氧化氢流，用于快速灭菌具有高容器生产能力的大型去污通道（11）。 蒸发器包括限定内孔或孔的加热块。 仔细监测净化隧道内的条件，以避免蒸汽冷凝，同时保持蒸气尽可能接近饱和极限。
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公开(公告)号：US20090130739A1
公开(公告)日：2009-05-21
申请号：US12319884
申请日：2009-01-13
IPC分类号： C12N1/36
CPC分类号： A61L2/186 , A01N25/00 , A01N25/30 , A61L2202/24
摘要： Compositions and methods for deactivating articles contaminated with nanobacteria, generally comprise a dispersant and/or a dissolution agent, and a deactivator. The methods and compositions of the invention are advantageously utilized to decontaminate and/or sterilize various articles such as medical and manufacturing devices or surfaces.
摘要翻译： 用于使受纳米细菌污染的制品失活的组合物和方法通常包含分散剂和/或溶解剂和失活剂。 本发明的方法和组合物有利地用于对诸如医疗和制造装置或表面的各种制品进行净化和/或消毒。
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公开(公告)号：US07265253B2
公开(公告)日：2007-09-04
申请号：US10280950
申请日：2002-10-25
申请人： Thaddeus J. Mielnik , David A. Karle , Alex D. Biggie , William John Thomas Biebesheimer , Peter A. Burke , Gerald E. McDonnell , Chad Rhodes , Elaine M. Kopis
发明人： Thaddeus J. Mielnik , David A. Karle , Alex D. Biggie , William John Thomas Biebesheimer , Peter A. Burke , Gerald E. McDonnell , Chad Rhodes , Elaine M. Kopis
IPC分类号： A62D3/00
CPC分类号： A61L2/208 , A61L2/206 , A61L2202/23 , G01N2001/025
摘要： Mail which may be contaminated with a biotoxin, such as Anthrax, is received in a preliminary sorting area (16) including a dirty side sorting room (40) that is sealed to the ambient environment. The mail is loaded into a pass-through decontamination system (22) in which the mail is sterilized or otherwise decontaminated. The mail is removed from the pass-through system in a second or clean room (18) which is isolated from the first. The mail is then sorted and processed in the lean room (18). In the event that the sorting room (40) becomes contaminated or is suspected of being contaminated by pathogenic biological or chemical agents, a spray system (86) supplies a decontamination gas into the preliminary sorting area (16) to decontaminate the dirty side sorting room (40), any equipment (42, 44) in the room, and any mail located in the room.
摘要翻译： 可能被生物毒素（例如炭疽）污染的邮件被接收在初步分拣区域（16）中，该初步分拣区域包括被密封到周围环境的脏侧分拣室（40）。 邮件被加载到通行去污系统（22）中，邮件被消毒或以其他方式去污染。 邮件从与第一个隔离的第二个或洁净室（18）中的直通系统中移除。 然后邮件在瘦室（18）中进行排序和处理。 如果分拣室（40）被污染或怀疑被病原生物或化学试剂污染，则喷雾系统（86）将净化气体供应到初步分拣区域（16）中以净化脏侧分拣室 （40），房间中的任何设备（42,44）以及位于房间中的任何邮件。
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