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公开(公告)号：US20110064819A1
公开(公告)日：2011-03-17
申请号：US12991543
申请日：2009-05-05
IPC分类号： A61K9/14 , A61K39/395 , A61P35/00 , A61P25/28 , B82Y5/00
CPC分类号： A61K9/5138 , A61K9/0019 , A61K9/0051 , A61K9/0085 , A61K9/1647 , A61K9/5153 , A61K9/5192 , A61K2039/505
摘要： The present invention provides methods of encapsulating biologically active agents such as proteins in particulate carriers such as nanoparticles using Hip agents. Also provided are compositions comprising particulate carriers obtainable by such methods and uses of such compositions in treatment.
摘要翻译： 本发明提供了使用Hip剂将生物活性剂如蛋白质包封在颗粒载体如纳米颗粒中的方法。 还提供了包含可通过这些方法和这些组合物在处理中的用途获得的颗粒载体的组合物。
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公开(公告)号：US20110045027A1
公开(公告)日：2011-02-24
申请号：US11917961
申请日：2006-06-20
CPC分类号： A61K39/21 , A61K39/12 , A61K2039/5256 , A61K2039/53 , A61K2039/54 , A61K2039/545 , A61K2039/55577 , C12N2710/10343 , C12N2740/16034
摘要： The present invention provides a novel adjuvant for polynucleotide vaccines, and in particular the present invention provides immunogenic compositions comprising a polynucleotide encoding an antigen capable of eliciting an immune response and an adjuvant comprising an immunostimulatory quantity of a gemini surfactant, or a derivative thereof.
摘要翻译： 本发明提供了用于多核苷酸疫苗的新型佐剂，特别是本发明提供了包含编码能够引发免疫应答的抗原的多核苷酸的免疫原性组合物和包含免疫刺激量的双子表面活性剂或其衍生物的佐剂。
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公开(公告)号：US20110064821A1
公开(公告)日：2011-03-17
申请号：US12991556
申请日：2009-05-05
IPC分类号： A61K9/14 , A61K38/16 , A61K39/395 , A61P27/02 , B82Y5/00
CPC分类号： A61K9/5138 , A61K9/0051 , A61K9/1647 , A61K9/5153 , A61K9/5192 , A61K2039/505 , Y02A50/394
摘要： The present invention provides methods of encapsulating biologically active agents such as proteins in particulate carriers such as nanoparticles. Also provided are methods of delivery of proteins across the blood brain barrier in nanoparticles, and uses of such compositions in treatment.
摘要翻译： 本发明提供了将生物活性剂如蛋白质包封在颗粒载体如纳米颗粒中的方法。 还提供了在纳米颗粒中通过血脑屏障传递蛋白质的方法，以及这些组合物在治疗中的用途。
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公开(公告)号：US20110059142A1
公开(公告)日：2011-03-10
申请号：US12991508
申请日：2009-05-05
申请人： Irene Papanicolaou
发明人： Irene Papanicolaou
CPC分类号： A61K9/5138 , A61K9/0019 , A61K9/0051 , A61K9/1647 , A61K9/5153 , A61K9/5192 , A61K2039/505
摘要： The present invention provides methods of encapsulating biologically active agents such as proteins in particulate carriers such as nanoparticles using Hip agents. Also provided are compositions comprising particulate carriers obtainable by such methods and uses of such compositions in treatment.
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公开(公告)号：US20110059167A1
公开(公告)日：2011-03-10
申请号：US12991521
申请日：2009-05-05
IPC分类号： A61K9/48 , A61K39/395 , A61P25/28 , A61P35/02 , A61P27/02 , A61P43/00 , A61P31/14 , A61P9/10 , A61K38/02 , B29D22/00
CPC分类号： A61K9/5138 , A61K9/0051 , A61K9/1647 , A61K9/5153 , A61K9/5192 , A61K2039/505 , Y02A50/394
摘要： The present invention provides methods of encapsulating biologically active agents such as proteins in particulate carriers such as nanoparticles using Hip agents. Also provided are compositions comprising particulate carriers obtainable by such methods and uses of such compositions in treatment.
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