公开(公告)号：US20200347096A1

公开(公告)日：2020-11-05

申请号：US16745520

申请日：2020-01-17

申请人： Igisu Co., Ltd.

发明人： Kyoko Endo ,  Yori Endo

IPC分类号： C07K7/64 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q19/02 ,  A61Q19/06 ,  A61Q19/10 ,  A61Q17/04 ,  A61Q19/08 ,  A61Q19/00 ,  C07K7/08 ,  A61Q7/00 ,  A61K8/64 ,  A61Q19/04

摘要： The present invention is aimed for providing a novel peptide with a high drug efficacy and strong effect, a medicament or external preparation comprising it, specifically a prophylactic or therapeutic for dermatitis, rhinitis or alopecia, or a hair growth stimulant, a hair growing agent, an antipruritic or a skin-care product. The present invention achieved said aim by providing a cyclic peptide having an amino acid sequence expressed by the Formula I or a derivative thereof or a pharmaceutically acceptable salt thereof, wherein the amino acid sequence does not have a peptide bond that is not between the amino acids constituting the amino acid sequence.

公开(公告)号：US12065512B2

公开(公告)日：2024-08-20

申请号：US16745520

申请日：2020-01-17

申请人： Igisu Co., Ltd.

发明人： Kyoko Endo ,  Yori Endo

IPC分类号： A61K38/00 ,  A61K8/64 ,  A61K38/10 ,  A61K38/12 ,  A61P17/14 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q7/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/04 ,  A61Q19/06 ,  A61Q19/08 ,  A61Q19/10 ,  C07K7/00 ,  C07K7/08 ,  C07K7/64

CPC分类号： C07K7/64 ,  A61K8/64 ,  A61K38/10 ,  A61K38/12 ,  A61P17/14 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q7/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/04 ,  A61Q19/06 ,  A61Q19/08 ,  A61Q19/10 ,  C07K7/08 ,  A61K38/00

摘要： The present invention is aimed for providing a novel peptide with a high drug efficacy and strong effect, a medicament or external preparation comprising it, specifically a prophylactic or therapeutic for dermatitis, rhinitis or alopecia, or a hair growth stimulant, a hair growing agent, an antipruritic or a skin-care product. The present invention achieved said aim by providing a cyclic peptide having an amino acid sequence expressed by the Formula I or a derivative thereof or a pharmaceutically acceptable salt thereof, wherein the amino acid sequence does not have a peptide bond that is not between the amino acids constituting the amino acid sequence.

公开(公告)号：US20210277062A9

公开(公告)日：2021-09-09

申请号：US16745520

申请日：2020-01-17

申请人： Igisu Co., Ltd.

发明人： Kyoko Endo ,  Yori Endo

IPC分类号： C07K7/64 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q19/02 ,  A61Q19/06 ,  A61Q19/10 ,  A61Q17/04 ,  A61Q19/08 ,  A61Q19/00 ,  C07K7/08 ,  A61Q7/00 ,  A61K8/64 ,  A61Q19/04

摘要： The present invention is aimed for providing a novel peptide with a high drug efficacy and strong effect, a medicament or external preparation comprising it, specifically a prophylactic or therapeutic for dermatitis, rhinitis or alopecia, or a hair growth stimulant, a hair growing agent, an antipruritic or a skin-care product. The present invention achieved said aim by providing a cyclic peptide having an amino acid sequence expressed by the Formula I or a derivative thereof or a pharmaceutically acceptable salt thereof, wherein the amino acid sequence does not have a peptide bond that is not between the amino acids constituting the amino acid sequence.

公开(公告)号：US20190119325A1

公开(公告)日：2019-04-25

申请号：US15749275

申请日：2016-08-01

申请人： IGISU Co., Ltd.

发明人： Kyoko Endo ,  Yori Endo

IPC分类号： C07K7/08 ,  A61K8/64 ,  A61K38/10 ,  A61K9/00 ,  A61P17/00 ,  A61P17/10 ,  A61P17/06 ,  A61Q19/08 ,  A61Q19/00 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q19/10 ,  A61P17/14 ,  A61P11/02

摘要： The present invention is aimed at providing a novel peptide with quick expression of drug efficacy/effect and long duration of maintaining amelioration, a medicament or an external preparation comprising the same, in particular a prophylactic or therapeutic for dermatitis, skin roughness, rhinitis, alopecia or thinning hair, or a hair growth stimulant, hair growing agent, an antipruritic or a skin-care product, etc. The present invention has reached said object by providing a cyclic peptide having an amino acid sequence expressed by the formula I or a derivative thereof or a pharmaceutically acceptable salt thereof, wherein the amino acid sequence has no peptide bond other than those which are formed between the amino acids constituting the amino acid sequence.

公开(公告)号：US20180066020A1

公开(公告)日：2018-03-08

申请号：US15122753

申请日：2016-05-27

申请人： IGISU Co., Ltd.

发明人： Kyoko Endo ,  Yori Endo

IPC分类号： C07K7/64 ,  A61Q19/02 ,  A61Q19/04 ,  A61Q19/06 ,  A61Q19/10 ,  A61Q5/02 ,  A61Q5/12

摘要： The present invention is aimed for providing a novel peptide with a high drug efficacy and strong effect, a medicament or external preparation comprising it, specifically a prophylactic or therapeutic for dermatitis, rhinitis or alopecia, or a hair growth stimulant, a hair growing agent, an antipruritic or a skin-care product. The present invention achieved said aim by providing a cyclic peptide having an amino acid sequence expressed by the Formula I or a derivative thereof or a pharmaceutically acceptable salt thereof, wherein the amino acid sequence does not have a peptide bond that is not between the amino acids constituting the amino acid sequence.