公开(公告)号：US11179724B2

公开(公告)日：2021-11-23

申请号：US16127882

申请日：2018-09-11

申请人： Illumina, Inc. ,  Illumina Cambridge Limited

发明人： Bradley Kent Drews ,  Gudrun Stengel ,  James Christopher Blake ,  Mohammed Kafeel Ahamed ,  Michael Steven Becker ,  Michael Dangelo ,  Mark J. Nibbe ,  Daniel L. Fuller ,  Oliver Jon Miller

IPC分类号： B01L3/00 ,  B01L9/00

摘要： The assembly includes a docking console and a manifold. The docking console includes a cartridge support surface having a first end and a second end. The manifold has one or more wells defined therein. The docking console further includes a manifold retention bracket to releasably hold the manifold against a fluid cartridge supported on the cartridge support surface at an interface position such that the one or more wells are in fluid communication with the fluid cartridge and a biased seal bar to press the fluid cartridge against the manifold held by the manifold retention bracket. A hydrophilic porous frit disposed within at least one of the wells and is to permit liquid to flow through the outlet aperture but prevent gas from passing through the outlet aperture.

公开(公告)号：US11975328B2

公开(公告)日：2024-05-07

申请号：US17507254

申请日：2021-10-21

申请人： Illumina, Inc. ,  Illumina Cambridge Limited

发明人： Bradley Kent Drews ,  Gudrun Stengel ,  James Christopher Blake ,  Mohammed Kafeel Ahamed ,  Michael Steven Becker ,  Michael Dangelo ,  Mark J. Nibbe ,  Daniel L. Fuller ,  Oliver Jon Miller

IPC分类号： B01L3/00 ,  B01L9/00

CPC分类号： B01L3/50853 ,  B01L3/502715 ,  B01L9/523 ,  B01L9/527 ,  B01L2200/025 ,  B01L2200/027 ,  B01L2200/0684 ,  B01L2200/0689 ,  B01L2300/041 ,  B01L2300/047 ,  B01L2300/048 ,  B01L2300/0681 ,  B01L2300/0819 ,  B01L2300/0829

摘要： The assembly includes a docking console and a manifold. The docking console includes a cartridge support surface having a first end and a second end. The manifold has one or more wells defined therein. The docking console further includes a manifold retention bracket to releasably hold the manifold against a fluid cartridge supported on the cartridge support surface at an interface position such that the one or more wells are in fluid communication with the fluid cartridge and a biased seal bar to press the fluid cartridge against the manifold held by the manifold retention bracket. A hydrophilic porous frit disposed within at least one of the wells and is to permit liquid to flow through the outlet aperture but prevent gas from passing through the outlet aperture.