专利检索 ap:("Illumina Cambridge Limited") AND inv:"Anno Koetje" 第 1 页

1.

发明授权
Nucleosides and nucleotides with 3′ acetal blocking group 有权

公开(公告)号：US11787831B2

公开(公告)日：2023-10-17

申请号：US17353512

申请日：2021-06-21

申请人： Illumina Cambridge Limited

发明人： Antoine Francais , Elena Cressina , Angelica Mariani , Adam Culley , Anno Koetje , Xiaohai Liu

IPC分类号： C07H19/073 , C07H19/173 , C12Q1/6869

CPC分类号： C07H19/073 , C07H19/173 , C12Q1/6869

摘要： Embodiments of the present disclosure relate to nucleotide and nucleoside molecules with acetal 3′-OH blocking groups. Also provided herein are methods to prepare such nucleotide and nucleoside molecules, and the uses of fully functionalized nucleotides containing the 3′ acetal blocking group for sequencing applications.