System and method for neural stimulation

    公开(公告)号:US08457734B2

    公开(公告)日:2013-06-04

    申请号:US11468135

    申请日:2006-08-29

    IPC分类号: A61N1/365

    摘要: Various aspects provide an implantable device. In various embodiments, the device comprises at least one port, where each port is adapted to connect a lead with an electrode to the device. The device further includes a stimulation platform, including a sensing circuit connected to the at least one port to sense an intrinsic cardiac signal and a stimulation circuit connected to the at least one port via a stimulation channel to deliver a stimulation signal through the stimulation channel to the electrode. The stimulation circuit is adapted to deliver stimulation signals through the stimulation channel for both neural stimulation therapy and CRM therapy. The sensing and stimulation circuits are adapted to perform CRM functions. The device further includes a controller connected to the sensing circuit and the stimulation circuit to control the neural stimulation therapy and the CRM therapy. Other aspects and embodiments are provided herein.

    SYSTEM AND METHOD FOR NEURAL STIMULATION
    2.
    发明申请
    SYSTEM AND METHOD FOR NEURAL STIMULATION 有权
    神经刺激的系统与方法

    公开(公告)号:US20080058871A1

    公开(公告)日:2008-03-06

    申请号:US11468135

    申请日:2006-08-29

    IPC分类号: A61N1/00

    摘要: Various aspects provide an implantable device. In various embodiments, the device comprises at least one port, where each port is adapted to connect a lead with an electrode to the device. The device further includes a stimulation platform, including a sensing circuit connected to the at least one port to sense an intrinsic cardiac signal and a stimulation circuit connected to the at least one port via a stimulation channel to deliver a stimulation signal through the stimulation channel to the electrode. The stimulation circuit is adapted to deliver stimulation signals through the stimulation channel for both neural stimulation therapy and CRM therapy. The sensing and stimulation circuits are adapted to perform CRM functions. The device further includes a controller connected to the sensing circuit and the stimulation circuit to control the neural stimulation therapy and the CRM therapy. Other aspects and embodiments are provided herein.

    摘要翻译: 各种方面提供可植入装置。 在各种实施例中,该装置包括至少一个端口,其中每个端口适于将引线与电极连接到该装置。 所述装置还包括刺激平台,包括连接到所述至少一个端口以感测固有心脏信号的感测电路和经由刺激通道连接到所述至少一个端口的刺激电路,以将刺激信号通过所述刺激通道传递到 电极。 刺激电路适于通过刺激通道递送刺激信号用于神经刺激治疗和CRM治疗。 感测和刺激电路适用于执行CRM功能。 该装置还包括连接到感测电路和刺激电路的控制器,以控制神经刺激疗法和CRM治疗。 本文提供了其它方面和实施例。

    Systems and methods for delivering electric current for spinal cord stimulation
    3.
    发明授权
    Systems and methods for delivering electric current for spinal cord stimulation 有权
    用于输送脊髓刺激电流的系统和方法

    公开(公告)号:US09259568B2

    公开(公告)日:2016-02-16

    申请号:US12431607

    申请日:2009-04-28

    IPC分类号: A61N1/05

    摘要: Various system embodiments comprise a lead having a distal end and a proximal end. The distal end includes a plurality of electrodes. The lead is configured to be fed into a dorsal epidural space of a human to a desired region of a spinal column and to be fed laterally to at least partially encircle a spinal cord in the desired region to place at least one stimulation electrode in position to stimulate a dorsal nerve root and at least another stimulation electrode in position to stimulate a ventral nerve root. The desired region may include cervical vertebrae, thoracic vertebrae, or lumbar vertebrae. Some embodiments stimulate the spinal cord in the T1-T5 region.

    摘要翻译: 各种系统实施例包括具有远端和近端的引线。 远端包括多个电极。 引线被配置为被馈送到人的背部硬膜外区域到脊柱的期望区域,并且被横向地供给至少部分地包围所需区域中的脊髓,以将至少一个刺激电极置于适当位置 刺激背神经根和至少另一个刺激电极,以刺激腹侧神经根。 所需区域可包括颈椎,胸椎或腰椎。 一些实施方案刺激T1-T5区域中的脊髓。

    SYSTEMS AND METHODS FOR DELIVERING VAGAL NERVE STIMULATION
    4.
    发明申请
    SYSTEMS AND METHODS FOR DELIVERING VAGAL NERVE STIMULATION 有权
    用于输送VAGAL NERVE刺激的系统和方法

    公开(公告)号:US20100010556A1

    公开(公告)日:2010-01-14

    申请号:US12487266

    申请日:2009-06-18

    IPC分类号: A61N1/36

    摘要: According to various method embodiments, a person is indicated for a therapy to treat a cardiovascular disease, and the therapy is delivered to the person to treat the cardiovascular disease. Delivering the therapy includes delivering a vagal stimulation therapy (VST) to a vagus nerve of the person at a therapeutically-effective intensity for the cardiovascular disease that is below an upper boundary at which upper boundary the VST would lower an intrinsic heart rate during the VST.

    摘要翻译: 根据各种方法实施例,指示一个人用于治疗心血管疾病的治疗,并且将该治疗递送给该人以治疗心血管疾病。 提供治疗包括将迷走神经刺激治疗(VST)以对于心血管疾病的治疗有效强度的人的迷走神经递送,所述心血管疾病低于VST在VST期间的上边界降低内在心率的上边界 。

    SYSTEMS AND METHODS FOR DELIVERING ELECTRIC CURRENT FOR SPINAL CORD STIMULATION
    5.
    发明申请
    SYSTEMS AND METHODS FOR DELIVERING ELECTRIC CURRENT FOR SPINAL CORD STIMULATION 有权
    用于输送脊髓刺激电流的系统和方法

    公开(公告)号:US20090270960A1

    公开(公告)日:2009-10-29

    申请号:US12431607

    申请日:2009-04-28

    IPC分类号: A61N1/00

    摘要: Various system embodiments comprise a lead having a distal end and a proximal end. The distal end includes a plurality of electrodes. The lead is configured to be fed into a dorsal epidural space of a human to a desired region of a spinal column and to be fed laterally to at least partially encircle a spinal cord in the desired region to place at least one stimulation electrode in position to stimulate a dorsal nerve root and at least another stimulation electrode in position to stimulate a ventral nerve root. The desired region may include cervical vertebrae, thoracic vertebrae, or lumbar vertebrae. Some embodiments stimulate the spinal cord in the T1-T5 region.

    摘要翻译: 各种系统实施例包括具有远端和近端的引线。 远端包括多个电极。 引线被配置为被馈送到人的背部硬膜外空间到脊柱的期望区域,并且被横向馈送以至少部分地环绕所需区域中的脊髓,以将至少一个刺激电极置于适当位置 刺激背神经根和至少另一个刺激电极,以刺激腹侧神经根。 所需区域可包括颈椎,胸椎或腰椎。 一些实施方案刺激T1-T5区域中的脊髓。

    SYSTEMS AND METHODS FOR DELIVERING VAGAL NERVE STIMULATION
    6.
    发明申请
    SYSTEMS AND METHODS FOR DELIVERING VAGAL NERVE STIMULATION 有权
    用于输送VAGAL NERVE刺激的系统和方法

    公开(公告)号:US20120197333A1

    公开(公告)日:2012-08-02

    申请号:US13444400

    申请日:2012-04-11

    IPC分类号: A61N1/365 A61N1/362

    摘要: According to various method embodiments, a person is indicated for a therapy to treat a cardiovascular disease, and the therapy is delivered to the person to treat the cardiovascular disease. Delivering the therapy includes delivering a vagal stimulation therapy (VST) to a vagus nerve of the person at a therapeutically-effective intensity for the cardiovascular disease that is below an upper boundary at which upper boundary the VST would lower an intrinsic heart rate during the VST.

    摘要翻译: 根据各种方法实施例,指示一个人用于治疗心血管疾病的治疗,并且将该治疗递送给该人以治疗心血管疾病。 提供治疗包括将迷走神经刺激治疗(VST)以对于心血管疾病的治疗有效强度的人的迷走神经递送,所述心血管疾病低于VST在VST期间的上边界降低内在心率的上边界 。

    SYSTEMS AND METHODS FOR SELECTIVELY STIMULATING NERVE ROOTS
    7.
    发明申请
    SYSTEMS AND METHODS FOR SELECTIVELY STIMULATING NERVE ROOTS 有权
    用于选择性刺激神经病变的系统和方法

    公开(公告)号:US20090270935A1

    公开(公告)日:2009-10-29

    申请号:US12431621

    申请日:2009-04-28

    IPC分类号: A61N1/36

    摘要: Various system embodiments comprise an implantable lead, an implantable housing, a neural stimulation circuit in the housing, and a controller in the housing and connected to the neural stimulation circuit. The lead has a proximal end and a distal end. The distal end is adapted to deliver neural stimulation pulses to the ventral nerve root and the dorsal nerve root. The proximal end of the lead is adapted to connect to the housing. The neural stimulation circuit is adapted to generate neural stimulation pulses to stimulate the ventral nerve root or the dorsal nerve root using the implantable lead. The controller is adapted to control the neural stimulation circuit to deliver a neural stimulation treatment.

    摘要翻译: 各种系统实施例包括可植入引线,可植入壳体,壳体中的神经刺激电路以及壳体中的控制器并连接到神经刺激电路。 引线具有近端和远端。 远端适于将神经刺激脉冲输送到腹侧神经根和背神经根。 引线的近端适于连接到外壳。 神经刺激电路适于产生神经刺激脉冲,以使用可植入引线刺激腹侧神经根或背神经根。 控制器适于控制神经刺激电路以递送神经刺激治疗。

    Systems and methods for selectively stimulating nerve roots
    10.
    发明授权
    Systems and methods for selectively stimulating nerve roots 有权
    选择性刺激神经根的系统和方法

    公开(公告)号:US08386045B2

    公开(公告)日:2013-02-26

    申请号:US12431621

    申请日:2009-04-28

    IPC分类号: A61N1/00

    摘要: Various system embodiments comprise an implantable lead, an implantable housing, a neural stimulation circuit in the housing, and a controller in the housing and connected to the neural stimulation circuit. The lead has a proximal end and a distal end. The distal end is adapted to deliver neural stimulation pulses to the ventral nerve root and the dorsal nerve root. The proximal end of the lead is adapted to connect to the housing. The neural stimulation circuit is adapted to generate neural stimulation pulses to stimulate the ventral nerve root or the dorsal nerve root using the implantable lead. The controller is adapted to control the neural stimulation circuit to deliver a neural stimulation treatment.

    摘要翻译: 各种系统实施例包括可植入引线,可植入壳体,壳体中的神经刺激电路以及壳体中的控制器并连接到神经刺激电路。 引线具有近端和远端。 远端适于将神经刺激脉冲输送到腹侧神经根和背神经根。 引线的近端适于连接到外壳。 神经刺激电路适于产生神经刺激脉冲,以使用可植入引线刺激腹侧神经根或背神经根。 控制器适于控制神经刺激电路以递送神经刺激治疗。