Compositions and Methods for Improving Rebaudioside M Solubility
    1.
    发明申请
    Compositions and Methods for Improving Rebaudioside M Solubility 审中-公开
    改善雷鲍迪苷M溶解度的组合物和方法

    公开(公告)号:US20150017284A1

    公开(公告)日:2015-01-15

    申请号:US14046514

    申请日:2013-10-04

    IPC分类号: A23L1/236 A23L2/60

    摘要: Rebaudioside M compositions with improved aqueous solubility and methods for preparing the same are provided herein. The rebaudioside M compositions include (i) disordered crystalline compositions comprising rebaudioside M and rebaudioside D, (ii) spray-dried compositions comprising rebaudioside M, rebaudioside D and steviol glycoside mixtures and/or rebaudioside B and/or NSF-02, (iii) spray-dried compositions comprising rebaudioside M, rebaudioside D and at least one surfactant, polymer, saponin, carbohydrate, polyol, preservative or a combination thereof. Sweetened compositions, such a beverages, containing the rebaudioside M compositions with improved water solubility are also provided herein.

    摘要翻译: 具有改善的水溶性的雷鲍迪甙M组合物及其制备方法在本文中提供。 新蛇菊苷M组合物包括(i)包含莱鲍迪甙M和莱鲍迪甙D的无序结晶组合物,(ii)包含莱鲍迪甙M,莱鲍迪甙D和甜菊糖糖苷混合物和/或莱鲍迪甙B和/或NSF-02的喷雾干燥组合物,(iii) 包含新蛇菊苷M,莱鲍迪甙D和至少一种表面活性剂,聚合物,皂角苷,碳水化合物,多元醇,防腐剂或其组合的喷雾干燥组合物。 本文还提供了含有具有改善的水溶性的新蛇菊苷M组合物的甜味组合物,如饮料。

    BEVERAGES CONTAINING RARE SUGARS
    3.
    发明申请

    公开(公告)号:US20140271996A1

    公开(公告)日:2014-09-18

    申请号:US14212410

    申请日:2014-03-14

    IPC分类号: A23L2/60

    CPC分类号: A23L2/60 A23L2/52 A23L2/54

    摘要: Beverages comprising rare sugars and sweetness enhancers are provided herein, wherein the sweetness enhancers are present at or below the sweetness recognition threshold concentration. Also provided are methods for improving the sweetness of a beverage comprising rare sugars by adding a sweetness enhancer in a concentration at or below its sweetness recognition threshold. Beverages comprising natural high potency sweeteners and rare sugars with sugar-like characteristics are also provided, wherein the natural high potency sweetener and rare sugars are present in particular weight ratios.

    Beverages containing rare sugars
    4.
    发明授权

    公开(公告)号:US09717267B2

    公开(公告)日:2017-08-01

    申请号:US14212410

    申请日:2014-03-14

    IPC分类号: A23L2/60 A23L2/52 A23L2/54

    CPC分类号: A23L2/60 A23L2/52 A23L2/54

    摘要: Beverages comprising rare sugars and sweetness enhancers are provided herein, wherein the sweetness enhancers are present at or below the sweetness recognition threshold concentration. Also provided are methods for improving the sweetness of a beverage comprising rare sugars by adding a sweetness enhancer in a concentration at or below its sweetness recognition threshold. Beverages comprising natural high potency sweeteners and rare sugars with sugar-like characteristics are also provided, wherein the natural high potency sweetener and rare sugars are present in particular weight ratios.

    BEVERAGES CONTAINING RARE SUGARS
    5.
    发明申请
    BEVERAGES CONTAINING RARE SUGARS 审中-公开
    含有稀有糖的饮料

    公开(公告)号:US20140272068A1

    公开(公告)日:2014-09-18

    申请号:US14050840

    申请日:2013-10-10

    IPC分类号: A23L2/60

    摘要: Beverages comprising rare sugars and sweetness enhancers are provided herein, wherein the sweetness enhancers are present at or below the sweetness recognition threshold concentration. Also provided are methods for improving the sweetness of a beverage comprising rare sugars by adding a sweetness enhancer in a concentration at or below its sweetness recognition threshold. Beverages comprising natural high potency sweeteners and rare sugars with sugar-like characteristics are also provided, wherein the natural high potency sweetener and rare sugars are present in particular weight ratios.

    摘要翻译: 本文提供了包含稀有糖和甜味增强剂的饮料,其中甜味增强剂存在于或低于甜度识别阈值浓度。 还提供了通过加入浓度等于或低于其甜度识别阈值的甜味增强剂来改善包含稀有糖的饮料的甜度的方法。 还提供包含天然高效甜味剂和具有糖样特征的稀有糖的饮料,其中天然高​​效甜味剂和稀有糖以特定重量比存在。

    Method for the asymmetric synthesis of beta-lactone compounds
    8.
    发明授权
    Method for the asymmetric synthesis of beta-lactone compounds 失效
    β-内酯化合物的不对称合成方法

    公开(公告)号:US07728153B2

    公开(公告)日:2010-06-01

    申请号:US11378961

    申请日:2006-03-16

    IPC分类号: C07D305/00

    摘要: The present invention features methods of treating a cancer in a subject by administering an effective amount of a beta-lactone to the subject. The invention also features methods of inhibiting angiogenesis in a subject by administering an effective amount of an inhibitor of fatty acid synthase to the subject. These methods can be used to treat a variety of cancers and other diseases and conditions. The invention also features methods of identifying beta-lactones and other compounds that can be used in the methods of the invention for the treatment of tumors, inhibition of angiogenesis, and the treatment of diseases and conditions that involve pathological angiogenesis. The invention also features methods of synthesizing beta-lactones and features novel beta-lactone compounds.

    摘要翻译: 本发明的特征在于通过向受试者施用有效量的β-内酯来治疗受试者的癌症的方法。 本发明还具有通过向受试者施用有效量的脂肪酸合酶抑制剂来抑制受试者血管生成的方法。 这些方法可用于治疗各种癌症和其他疾病和病症。 本发明还涉及鉴定可用于本发明治疗肿瘤,抑制血管发生以及涉及病理性血管生成的疾病和病症的治疗的β-内酯和其它化合物的方法。 本发明还具有合成β-内酯并具有新型β-内酯化合物特征的方法。

    Novel method for the asymmetric synthesis of beta-lactone compounds
    9.
    发明申请
    Novel method for the asymmetric synthesis of beta-lactone compounds 失效
    β-内酯化合物的不对称合成的新方法

    公开(公告)号:US20060258620A1

    公开(公告)日:2006-11-16

    申请号:US11378961

    申请日:2006-03-16

    摘要: The present invention features methods of treating a cancer in a subject by administering an effective amount of a beta-lactone to the subject. The invention also features methods of inhibiting angiogenesis in a subject by administering an effective amount of an inhibitor of fatty acid synthase to the subject. These methods can be used to treat a variety of cancers and other diseases and conditions. The invention also features methods of identifying beta-lactones and other compounds that can be used in the methods of the invention for the treatment of tumors, inhibition of angiogenesis, and the treatment of diseases and conditions that involve pathological angiogenesis. The invention also features methods of synthesizing beta-lactones and features novel beta-lactone compounds.

    摘要翻译: 本发明的特征在于通过向受试者施用有效量的β-内酯来治疗受试者的癌症的方法。 本发明还具有通过向受试者施用有效量的脂肪酸合酶抑制剂来抑制受试者血管生成的方法。 这些方法可用于治疗各种癌症和其他疾病和病症。 本发明还涉及鉴定可用于本发明治疗肿瘤,抑制血管发生以及涉及病理性血管生成的疾病和病症的治疗的β-内酯和其它化合物的方法。 本发明还具有合成β-内酯并具有新型β-内酯化合物特征的方法。

    Method for the asymmetric synthesis of beta-lactone compounds
    10.
    发明授权
    Method for the asymmetric synthesis of beta-lactone compounds 失效
    β-内酯化合物的不对称合成方法

    公开(公告)号:US08124794B2

    公开(公告)日:2012-02-28

    申请号:US12620412

    申请日:2009-11-17

    IPC分类号: C07D305/00

    摘要: The present invention features methods of treating a cancer in a subject by administering an effective amount of a beta-lactone to the subject. The invention also features methods of inhibiting angiogenesis in a subject by administering an effective amount of an inhibitor of fatty acid synthase to the subject. These methods can be used to treat a variety of cancers and other diseases and conditions. The invention also features methods of identifying beta-lactones and other compounds that can be used in the methods of the invention for the treatment of tumors, inhibition of angiogenesis, and the treatment of diseases and conditions that involve pathological angiogenesis. The invention also features methods of synthesizing beta-lactones and features novel beta-lactone compounds.

    摘要翻译: 本发明的特征在于通过向受试者施用有效量的β-内酯来治疗受试者的癌症的方法。 本发明还具有通过向受试者施用有效量的脂肪酸合酶抑制剂来抑制受试者血管生成的方法。 这些方法可用于治疗各种癌症和其他疾病和病症。 本发明还涉及鉴定可用于本发明治疗肿瘤,抑制血管发生以及涉及病理性血管生成的疾病和病症的治疗的β-内酯和其它化合物的方法。 本发明还具有合成β-内酯并具有新型β-内酯化合物特征的方法。