公开(公告)号：US20180169295A1

公开(公告)日：2018-06-21

申请号：US15388980

申请日：2016-12-22

Applicant: Industrial Technology Research Institute

Inventor： Ming-Chia YANG ,  Wei-Hong CHANG ,  Yun-Han LIN ,  Kun-Mao KUO ,  Li-Jie LIN ,  Tai-Horng YOUNG

IPC: A61L24/04

CPC classification number: A61L24/043 ,  Y02P20/149 ,  C08L67/04 ,  C08L5/04

Abstract: The present disclosure provides a film composed of a polymer mixture, wherein the polymer mixture includes: a hydrophobic composition including polycaprolactone (PCL); and at least one hydrophilic polymer selected from a group consisting of: alginate, gelatin, chitosan, hyaluronic acid, collagen, demineralized bone matrix (DSM), carboxymethyl cellulose (CMC), fibrin, polyoxyethylene, polyethylene glycol (PEG) and polyvinylpyrrolidone, wherein the weight ratio of the hydrophobic composition to the at least one hydrophilic polymer is about 1:0.01-100, and wherein the film has the effect of preventing leakage from a surgical wound or a diffuse wound.

公开(公告)号：US20220388293A1

公开(公告)日：2022-12-08

申请号：US17885874

申请日：2022-08-11

Applicant: Industrial Technology Research Institute

Inventor： Hsin-Hsin SHEN ,  Yu-Chi WANG ,  Ming-Chia YANG ,  Yu-Bing LIOU ,  Wei-Hong CHANG ,  Yun-Han LIN ,  Hsin-Yi HSU ,  Yun-Chung TENG ,  Chia-Jung LU ,  Yi-Hsuan LEE ,  Jian-Wei LIN ,  Kun-Mao KUO ,  Ching-Mei CHEN

IPC: B32B27/36 ,  B32B27/24 ,  B32B27/30 ,  B05D7/00 ,  B05D5/08

Abstract: A method for preparing a bifunctional film, including: (a) drying a first polymer solution to form a film to form an anti-adhesion layer, and (b) drying a second polymer solution over the anti-adhesion layer to form a film to form an attachment layer. The first polymer solution includes a first hydrophobic solution and a first hydrophilic solution, and in the first polymer solution, the weight ratio of the solute of the first hydrophobic solution to the solute of the first hydrophilic solution is 1:0.01-1. Moreover, the second polymer solution is composed of a second hydrophilic solution.

公开(公告)号：US20200247101A1

公开(公告)日：2020-08-06

申请号：US16675838

申请日：2019-11-06

Applicant: Industrial Technology Research Institute

Inventor： Hsin-Hsin SHEN ,  Yu-Chi WANG ,  Ming-Chia YANG ,  Yu-Bing LIOU ,  Wei-Hong CHANG ,  Yun-Han LIN ,  Hsin-Yi HSU ,  Yun-Chung TENG ,  Chia-Jung LU ,  Yi-Hsuan LEE ,  Jian-Wei LIN ,  Kun-Mao KUO ,  Ching-Mei CHEN

IPC: B32B27/36 ,  B32B27/24 ,  B32B27/30

Abstract: A method for preparing a bifunctional film, including: (a) drying a first polymer solution to form a film to form an anti-adhesion layer; and (b) drying a second polymer solution over the anti-adhesion layer to form a film to form an attachment layer. The first polymer solution includes a first hydrophobic solution and a first hydrophilic solution, and in the first polymer solution, the weight ratio of the solute of the first hydrophobic solution to the solute of the first hydrophilic solution 1:0.01-1. Moreover, the second polymer solution consists of a second hydrophilic solution.

公开(公告)号：US20180200403A1

公开(公告)日：2018-07-19

申请号：US15850902

申请日：2017-12-21

Applicant: Industrial Technology Research Institute

Inventor： Wei-Hong CHANG ,  Ming-Chia YANG ,  Yun-Han LIN ,  Kun-Mao KUO ,  Yu-Chi WANG ,  Hsin-Hsin SHEN ,  Li-Jie LIN

IPC: A61L24/04 ,  A61L24/00 ,  A61B17/06

CPC classification number: A61L24/043 ,  A61B17/04 ,  A61B17/06166 ,  A61B17/1114 ,  A61B2017/00004 ,  A61B2017/00526 ,  A61B2017/00575 ,  A61B2017/00597 ,  A61B2017/00659 ,  A61B2017/00818 ,  A61B2017/00938 ,  A61B2017/00942 ,  A61B2017/00964 ,  A61B2017/0495 ,  A61B2017/1132 ,  A61F13/15 ,  A61L24/0042 ,  A61L24/0084 ,  A61L24/0094 ,  C08L67/04

Abstract: The present disclosure provides a film composed of a polymer mixture, wherein the polymer mixture includes: a hydrophobic composition including polycaprolactone (PCL); and at least one hydrophilic polymer selected from a group consisting of alginate, gelatin, hyaluronic acid, polyvinyl alcohol (PVA), carboxymethyl cellulose (CMC), polyethylene glycol (PEG), collagen, demineralized bone matrix (DBM), bone morphogenetic protein (BMP), albumin, chitosan, fibrin, polyoxyethylene, polyvinylpyrrolidone, wherein the weight ratio of the hydrophobic composition to the hydrophilic polymer is about 1:0.01-100, and wherein the film has the effect of preventing leakage from a surgical wound or a diffuse wound.