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公开(公告)号：US20180296435A1
公开(公告)日：2018-10-18
申请号：US16014169
申请日：2018-06-21
CPC分类号： A61H39/002 , A61H39/02 , A61H2201/5005 , A61H2201/5007 , A61H2201/5023 , A61H2201/5033 , A61H2201/5038 , A61H2201/5058 , A61H2205/027 , A61H2230/105 , A61H2230/405 , A61H2230/505 , A61H2230/605 , A61N1/0551 , A61N1/36135
摘要： An auricular peripheral nerve field stimulator includes an electrical stimulation device for generating electrical stimulation signals, at least one therapy electrode electrically coupled to the stimulation device and configured for percutaneous insertion into an auricle of a human ear near at least one neurovascular bundle, a processor, and a memory with software executable by the processor to (i) control the stimulation device to generate and deliver to the inserted at least one therapy electrode the stimulation signals at a selected frequency with one of a positive and a negative pulse relative to a reference to stimulate at least one auricular peripheral nerve field within the auricle, (ii) continually repeat (i) for a first duration, (iii) following expiration of the first duration, control the stimulation device to generate no stimulation signals for a second duration, and (iv) repeat (i) through (iii) with the stimulation signals having a modulated frequency.
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公开(公告)号：US09839577B2
公开(公告)日：2017-12-12
申请号：US15595185
申请日：2017-05-15
CPC分类号： A61H39/002 , A61H39/02 , A61H2201/5005 , A61H2201/5007 , A61H2201/5023 , A61H2201/5033 , A61H2201/5038 , A61H2201/5058 , A61H2205/027 , A61H2230/105 , A61H2230/405 , A61H2230/505 , A61H2230/605 , A61N1/0551 , A61N1/36135
摘要： An auricular peripheral nerve field stimulator system includes an electrical stimulation device for generating electrical stimulation signals and a plurality of therapy electrodes each electrically coupled to the electrical stimulation device and each including a plurality of needles for percutaneous insertion into an auricle of a human ear near at least one neural vascular bundle located therein. In some embodiments, at least one reference electrode electrically is coupled to the electrical stimulation device and includes at least one needle for percutaneous insertion into or adjacent the auricle to provide a ground reference for the electrical stimulation device. The generated electrical stimulation signals are, in any case, delivered by the percutaneously inserted needles to stimulate an auricular peripheral nerve field within the auricle.
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公开(公告)号：US10413719B2
公开(公告)日：2019-09-17
申请号：US15488416
申请日：2017-04-14
IPC分类号： A61N1/05 , A61N1/36 , A61K31/485
摘要： A method for treating pain or discomfort in a patient is disclosed. The method comprises stimulating a cranial nerve with an electrical signal. The pain or discomfort may be a withdrawal symptom. The cranial nerve may be in an auricular area of the patient. The cranial nerve may be cranial nerve V, cranial nerve VII, cranial nerve IX, cranial nerve X, or branches of greater and lesser occipital nerves thereof and their associated neurovascular bundles. The withdrawal symptom may result from cessation of an opioid. The method may further comprise administering a secondary drug treats one or more of the withdrawal symptoms and addiction. The secondary drug may be administered about one day to about one week after initiating the stimulating step.
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公开(公告)号：US20180064603A1
公开(公告)日：2018-03-08
申请号：US15811278
申请日：2017-11-13
CPC分类号： A61H39/002 , A61H39/02 , A61H2201/5005 , A61H2201/5007 , A61H2201/5023 , A61H2201/5033 , A61H2201/5038 , A61H2201/5058 , A61H2205/027 , A61H2230/105 , A61H2230/405 , A61H2230/505 , A61H2230/605 , A61N1/0551 , A61N1/36135
摘要： An auricular peripheral nerve field stimulator system includes an electrical stimulation device for generating electrical stimulation signals and a plurality of therapy electrodes electrically coupled thereto, each of the therapy electrodes including at least one needle for percutaneous insertion into an auricle of a human ear near at least one neurovascular bundle located therein. At least one of the therapy electrodes includes a plurality of such needles for percutaneous insertion into the auricle near the at least one neurovascular bundle. In some embodiments, at least one reference electrode electrically is coupled to the electrical stimulation device and includes at least one needle for percutaneous insertion into or adjacent the auricle to provide a ground reference for the electrical stimulation device. The generated electrical stimulation signals are, in any case, delivered by the percutaneously inserted needles to stimulate at least one auricular peripheral nerve field within the auricle.
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公开(公告)号：US11369791B2
公开(公告)日：2022-06-28
申请号：US17040766
申请日：2019-04-25
摘要： An auricular nerve field stimulation device may include a first plurality of electrodes arranged to contact a ventral aspect of an auricle, a second plurality of electrodes arranged to contact a dorsal aspect of the auricle, and electrical circuitry coupled to the electrodes and configured to selectively apply electrical stimulation signals to the electrodes to cause a first set of trans-auricular currents to flow through the auricle between the first plurality of electrodes and respective ones of the second plurality of electrodes paired therewith according to a first pairing, and to cause a second set of trans-auricular currents to flow through the auricle between the first plurality of electrodes and respective ones of the second plurality of electrodes paired therewith according to a second pairing different from the first pairing, the first and second sets of trans-auricular currents to stimulate at least one auricular nerve field within the auricle.
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公开(公告)号：US11331473B2
公开(公告)日：2022-05-17
申请号：US16534159
申请日：2019-08-07
IPC分类号： A61N1/05 , A61N1/36 , A61K31/485
摘要： A method for treating pain or discomfort in a patient is disclosed. The method comprises stimulating a cranial nerve with an electrical signal. The pain or discomfort may be a withdrawal symptom. The cranial nerve may be in an auricular area of the patient. The cranial nerve may be cranial nerve V, cranial nerve VII, cranial nerve IX, cranial nerve X, or branches of greater and lesser occipital nerves thereof and their associated neurovascular bundles. The withdrawal symptom may result from cessation of an opioid. The method may further comprise administering a secondary drug treats one or more of the withdrawal symptoms and addiction. The secondary drug may be administered about one day to about one week after initiating the stimulating step.
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公开(公告)号：US10010479B2
公开(公告)日：2018-07-03
申请号：US15811278
申请日：2017-11-13
CPC分类号： A61H39/002 , A61H39/02 , A61H2201/5005 , A61H2201/5007 , A61H2201/5023 , A61H2201/5033 , A61H2201/5038 , A61H2201/5058 , A61H2205/027 , A61H2230/105 , A61H2230/405 , A61H2230/505 , A61H2230/605 , A61N1/0551 , A61N1/36135
摘要： An auricular peripheral nerve field stimulator system includes an electrical stimulation device for generating electrical stimulation signals and a plurality of therapy electrodes electrically coupled thereto, each of the therapy electrodes including at least one needle for percutaneous insertion into an auricle of a human ear near at least one neurovascular bundle located therein. At least one of the therapy electrodes includes a plurality of such needles for percutaneous insertion into the auricle near the at least one neurovascular bundle. In some embodiments, at least one reference electrode electrically is coupled to the electrical stimulation device and includes at least one needle for percutaneous insertion into or adjacent the auricle to provide a ground reference for the electrical stimulation device. The generated electrical stimulation signals are, in any case, delivered by the percutaneously inserted needles to stimulate at least one auricular peripheral nerve field within the auricle.
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公开(公告)号：US20170246081A1
公开(公告)日：2017-08-31
申请号：US15595185
申请日：2017-05-15
CPC分类号： A61H39/002 , A61H39/02 , A61H2201/5005 , A61H2201/5007 , A61H2201/5023 , A61H2201/5033 , A61H2201/5038 , A61H2201/5058 , A61H2205/027 , A61H2230/105 , A61H2230/405 , A61H2230/505 , A61H2230/605 , A61N1/0551 , A61N1/36135
摘要： An auricular peripheral nerve field stimulator system includes an electrical stimulation device for generating electrical stimulation signals and a plurality of therapy electrodes each electrically coupled to the electrical stimulation device and each including a plurality of needles for percutaneous insertion into an auricle of a human ear near at least one neural vascular bundle located therein. In some embodiments, at least one reference electrode electrically is coupled to the electrical stimulation device and includes at least one needle for percutaneous insertion into or adjacent the auricle to provide a ground reference for the electrical stimulation device. The generated electrical stimulation signals are, in any case, delivered by the percutaneously inserted needles to stimulate an auricular peripheral nerve field within the auricle.
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公开(公告)号：US20210322268A1
公开(公告)日：2021-10-21
申请号：US17363620
申请日：2021-06-30
摘要： An auricular peripheral nerve field stimulator includes at least one therapy electrode configured for percutaneous insertion into an auricle of a human ear near at least one neurovascular bundle, and an electrical stimulation device electrically coupled to the at least one therapy electrode, the electrical stimulation device programmed to generate and deliver electrical stimulation signals, with defined stimulation parameters, to the percutaneously inserted at least one therapy electrode to stimulate at least one auricular peripheral nerve field within the auricle, the defined stimulation parameters including a defined signal amplitude, a defined pulse frequency, a defined pulse width, a defined duty cycle and a defined stimulation signal duration.
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公开(公告)号：US11077019B2
公开(公告)日：2021-08-03
申请号：US16408004
申请日：2019-05-09
摘要： An auricular peripheral nerve field stimulator includes at least one therapy electrode configured for percutaneous insertion into an auricle of a human ear near at least one neurovascular bundle, and an electrical stimulation device electrically coupled to the at least one therapy electrode, the electrical stimulation device programmed to (i) generate and deliver electrical stimulation signals to the inserted at least one therapy electrode at a selected frequency for a selected duration to stimulate at least one auricular peripheral nerve field within the auricle, and (ii) repeat (i) with the stimulation signals having a modulated frequency.
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