公开(公告)号：US20250043314A1

公开(公告)日：2025-02-06

申请号：US18717586

申请日：2022-12-19

Applicant: Inscripta, Inc.

Inventor： Erik Zimmerman ,  Emily Feldman ,  Christian Siltanen ,  Marina Barreto Felisbino

IPC: C12N15/90 ,  C12N9/12 ,  C12N9/22 ,  C12N15/11 ,  C12Q1/6869

Abstract: The present disclosure provides compositions of matter, methods and instruments for nucleic acid-guided nickase/reverse transcriptase fusion enzyme editing of nucleic acids in live mammalian cells, and for tracking of editing events.

公开(公告)号：US20210214672A1

公开(公告)日：2021-07-15

申请号：US17140059

申请日：2021-01-02

Applicant: Inscripta, Inc.

Inventor： Aamir Mir ,  Erik Zimmerman ,  Emily Feldman ,  Benjamin Mijts ,  Andrew Garst

IPC: C12M1/36 ,  C12N15/10

Abstract: The present disclosure provides compositions, automated multi-module instruments and methods to increase the percentage of edited mammalian cells in a cell population when employing nucleic-acid guided editing.

公开(公告)号：US20210214671A1

公开(公告)日：2021-07-15

申请号：US16740420

申请日：2020-01-11

Applicant: Inscripta, Inc.

Inventor： Aamir Mir ,  Erik Zimmerman ,  Emily Feldman ,  Benjamin Mijts ,  Andrew Garst

IPC: C12M1/36 ,  C12N15/10

Abstract: The present disclosure provides compositions, automated multi-module instruments and methods to increase the percentage of edited mammalian cells in a cell population when employing nucleic-acid guided editing.

公开(公告)号：US10689669B1

公开(公告)日：2020-06-23

申请号：US16740418

申请日：2020-01-11

Applicant: Inscripta, Inc.

Inventor： Emily Feldman ,  Benjamin Mijts ,  Aamir Mir ,  Erik Zimmerman ,  Andrew Garst

IPC: C12M3/00 ,  C12M1/00 ,  C12N15/87 ,  C12M1/34

Abstract: The present disclosure provides automated multi-module instruments, compositions and methods to increase the percentage of edited mammalian cells in a cell population when employing nucleic-acid guided editing.