公开(公告)号：US11746347B2

公开(公告)日：2023-09-05

申请号：US17679203

申请日：2022-02-24

Applicant: Inscripta, Inc.

Inventor： Miles Gander ,  Tian Tian ,  Skylar Stefani ,  Patrick Westfall

IPC: C12N15/10

CPC classification number: C12N15/1037

Abstract: The present disclosure provides compositions of matter, methods and instruments for editing nucleic acids in live yeast cells.

公开(公告)号：US11136572B2

公开(公告)日：2021-10-05

申请号：US17230241

申请日：2021-04-14

Applicant: Inscripta, Inc.

Inventor： Miles Gander ,  Tian Tian ,  Skylar Stefani ,  Patrick Westfall

IPC: C12N15/10

Abstract: The present disclosure provides compositions of matter, methods and instruments for editing nucleic acids in live yeast cells.

公开(公告)号：US11274296B2

公开(公告)日：2022-03-15

申请号：US17463956

申请日：2021-09-01

Applicant: Inscripta, Inc.

Inventor： Miles Gander ,  Tian Tian ,  Skylar Stefani ,  Patrick Westfall

IPC: C12N15/10

Abstract: The present disclosure provides compositions of matter, methods and instruments for editing nucleic acids in live yeast cells.

公开(公告)号：US20210238586A1

公开(公告)日：2021-08-05

申请号：US17230241

申请日：2021-04-14

Applicant: Inscripta, Inc.

Inventor： Miles Gander ,  Tian Tian ,  Skylar Stefani ,  Patrick Westfall

IPC: C12N15/10

Abstract: The present disclosure provides compositions of matter, methods and instruments for editing nucleic acids in live yeast cells.

公开(公告)号：US20230012154A1

公开(公告)日：2023-01-12

申请号：US17679203

申请日：2022-02-24

Applicant: Inscripta, Inc.

Inventor： Miles Gander ,  Tian Tian ,  Skylar Stefani ,  Patrick Westfall

IPC: C12N15/10

Abstract: The present disclosure provides compositions of matter, methods and instruments for editing nucleic acids in live yeast cells.

公开(公告)号：US20220389461A1

公开(公告)日：2022-12-08

申请号：US17752122

申请日：2022-05-24

Applicant: Inscripta, Inc.

Inventor： Randy Lacey ,  Bryan Leland ,  Eileen Spindler ,  Patrick Westfall ,  Skylar Stefani ,  Catherine Baranowski

IPC: C12N15/90 ,  G16B20/20

Abstract: The present disclosure relates to automated multi-module instruments, compositions and methods for performing nucleic acid-guided nuclease editing; specifically, methods, instruments, systems, and nucleic acids synthetic cassettes that improve the efficiency of gene editing using CRISPR enzymes in diploid cells—either on both chromosomes or selectively in one chromosome—without incurring loss of heterozygosity (LOH) and its often deleterious effects.

公开(公告)号：US20210395727A1

公开(公告)日：2021-12-23

申请号：US17463956

申请日：2021-09-01

Applicant: Inscripta, Inc.

Inventor： Miles Gander ,  Tian Tian ,  Skylar Stefani ,  Patrick Westfall

IPC: C12N15/10

Abstract: The present disclosure provides compositions of matter, methods and instruments for editing nucleic acids in live yeast cells.