公开(公告)号：US20240342204A1

公开(公告)日：2024-10-17

申请号：US18294592

申请日：2022-08-05

Applicant: Intervet Inc.

Inventor： Edward Murray ,  Ralf Warrass ,  Joachim Ullrich ,  Basav Hangalapura Nagaraj ,  Willem Huisman

IPC: A61K31/7068 ,  A61P31/14 ,  A61P31/16 ,  A61P37/04

CPC classification number: A61K31/7068 ,  A61P31/14 ,  A61P31/16 ,  A61P37/04

Abstract: A method of preventing or treating a viral disease in an animal comprising administering to the animal a pharmaceutical composition comprising an antiviral nucleoside β-D-N(4)-hydroxycytidine (NHC) or a prodrug or salt thereof and a pharmaceutically acceptable carrier and wherein the viral disease is Porcine Reproductive and Respiratory Syndrome (PRRS), Bovine Respiratory Disease (BRD), Equine Influenza, Canine Distemper, Canine Respiratory Disease, Feline Infectious Peritonitis, Feline Viral Rhinotracheitis, or Feline Immunodeficiency.

公开(公告)号：US20240058366A1

公开(公告)日：2024-02-22

申请号：US18257815

申请日：2021-12-23

Applicant: Intervet Inc.

Inventor： Ralf Warrass ,  Joachim Ullrich

IPC: A61K31/7048 ,  A61P31/04 ,  A61K45/06 ,  A61K9/00

CPC classification number: A61K31/7048 ,  A61P31/04 ,  A61K45/06 ,  A61K9/0041

Abstract: This invention relates to methods of treatment and prevention of mastitis in animals by orthosomycin antimicrobial compounds.

公开(公告)号：US11406617B2

公开(公告)日：2022-08-09

申请号：US16472084

申请日：2017-12-22

Applicant: Intervet Inc.

Inventor： Thorsten Meyer ,  Ralf Warrass ,  Joachim Ullrich ,  Michael Berger ,  Michael Linder

IPC: A61K31/27 ,  A61P31/04 ,  A61P11/00 ,  A61K9/00 ,  A61K31/166 ,  A61K31/222 ,  A61K31/357 ,  A61K31/40 ,  A61K31/445 ,  A61K31/472 ,  A61K31/495 ,  A61K31/5377 ,  A61K31/54 ,  A61K31/695

Abstract: The present invention provides compounds for use in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).

公开(公告)号：US12227485B2

公开(公告)日：2025-02-18

申请号：US17253346

申请日：2019-06-24

Applicant: Intervet Inc.

Inventor： Thorsten Meyer ,  Michael Berger ,  Ralf Warrass ,  Joachim Ullrich

IPC: C07D239/94 ,  A61P11/00 ,  A61P31/04 ,  C07D217/22 ,  C07D275/04

Abstract: The present invention discloses compounds that are useful in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).

公开(公告)号：US12157717B2

公开(公告)日：2024-12-03

申请号：US17253437

申请日：2019-06-24

Applicant: Intervet Inc.

Inventor： Thorsten Meyer ,  Michael Berger ,  Ralf Warrass ,  Joachim Ullrich

IPC: C07C259/06 ,  A61P31/04 ,  C07C333/20 ,  C07D213/36 ,  C07D277/28 ,  C07D307/52

Abstract: The present invention provides compounds of formula (I) for use in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).

公开(公告)号：US20210347730A1

公开(公告)日：2021-11-11

申请号：US17253437

申请日：2019-06-24

Applicant: Intervet Inc.

Inventor： Thorsten Meyer ,  Michael Berger ,  Ralf Warrass ,  Joachim Ullrich

IPC: C07C259/06 ,  A61P31/04

Abstract: The present invention provides compounds of formula (I) for use in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).

公开(公告)号：US20210292284A1

公开(公告)日：2021-09-23

申请号：US17253346

申请日：2019-06-24

Applicant: Intervet Inc.

Inventor： Thorsten Meyer ,  Michael Berger ,  Ralf Warrass ,  Joachim Ullrich

IPC: C07D239/94 ,  A61P31/04 ,  C07D217/22 ,  C07D275/04

Abstract: The present invention discloses compounds that are useful in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD)

公开(公告)号：US20250057790A1

公开(公告)日：2025-02-20

申请号：US18721947

申请日：2022-12-23

Applicant: Intervet Inc.

Inventor： Chen-Chao Wang ,  Thorsten Meyer ,  Ralf Warrass ,  Joachim Ullrich

IPC: A61K31/166 ,  A61K9/00 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61P31/04

Abstract: An injectable pharmaceutical composition for treating a bacterial infection in an animal comprising an effective amount of a compound of Formula (I) or salt thereof, and a pharmaceutically acceptable carrier, wherein the injectable pharmaceutical composition is both efficacious and safe.

公开(公告)号：US12077488B2

公开(公告)日：2024-09-03

申请号：US17316034

申请日：2021-05-10

Applicant: Intervet Inc.

Inventor： Michael Berger ,  Thorsten Meyer ,  Joachim Ullrich ,  Ralf Warrass

IPC: A61K31/165 ,  A61P11/00 ,  A61P31/04 ,  C07C259/06 ,  C07C317/50 ,  C07C323/60 ,  C07D205/04 ,  C07D207/14 ,  C07D213/56 ,  C07D217/18 ,  C07D233/64 ,  C07D235/14 ,  C07D259/00 ,  C07D267/10 ,  C07D277/28 ,  C07D295/00 ,  C07D295/155 ,  C07D307/52 ,  C07D307/56 ,  C07D317/50 ,  C07D333/20 ,  C07D405/12 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12

CPC classification number: C07C259/06 ,  A61P11/00 ,  A61P31/04 ,  C07C317/50 ,  C07C323/60 ,  C07D213/56 ,  C07D217/18 ,  C07D235/14 ,  C07D267/10 ,  C07D277/28 ,  C07D295/155 ,  C07D307/52 ,  C07D333/20 ,  C07D405/12 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12 ,  C07C2601/02 ,  C07C2601/04 ,  C07C2601/08 ,  C07C2601/14 ,  C07C2601/16

Abstract: The present invention discloses compounds that are useful in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).

公开(公告)号：US20190352256A1

公开(公告)日：2019-11-21

申请号：US16472001

申请日：2017-12-22

Applicant: Intervet Inc.

Inventor： Michael Berger ,  Thorsten Meyer ,  Joachim Ullrich ,  Ralf Warrass

IPC: C07C259/06 ,  A61P31/04 ,  C07D277/28 ,  C07D213/56 ,  C07D333/20 ,  C07D307/52 ,  C07D217/18 ,  C07D295/155 ,  C07D417/12 ,  C07D409/12 ,  C07D405/12 ,  C07D235/14 ,  C07D267/10 ,  C07D413/12 ,  C07C323/60 ,  C07C317/50 ,  A61P11/00

Abstract: The present invention discloses compounds of formula (I) that are useful in the treatment of respiratory diseases of animals, especially Bovine or Swine Respiratory disease (BRD and SRD).