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    A METHOD TO PURIFY COCCIDIAL OOCYSTS FROM ANIMAL FAECES, A SYSTEM SUITABLE FOR APPLYING THIS METHOD AND OOCYSTS OBTAINED THEREWITH
    1.
    发明申请
    A METHOD TO PURIFY COCCIDIAL OOCYSTS FROM ANIMAL FAECES, A SYSTEM SUITABLE FOR APPLYING THIS METHOD AND OOCYSTS OBTAINED THEREWITH 审中-公开

    公开(公告)号：US20170121670A1

    公开(公告)日：2017-05-04

    申请号：US15300499

    申请日：2015-04-02

    申请人： INTERVET INTERNATIONAL B.V. ,  INTERVET INC.

    发明人： Koen Gevers ,  Theodorus Petrus Maria Schetters

    IPC分类号： C12N1/10

    摘要： The invention pertains to a method to purify coccidial oocysts having dimensions between Dmin and Dmax from faeces comprising the steps of collecting the faeces containing the coccidial oocysts from host animals, diluting the faeces in an aqueous medium, separating a coarse fraction comprising macroscopic particulate matter from the diluted faeces and collecting an aqueous fraction containing the oocysts, characterised in that the method further comprises sieving the aqueous fraction over a first sieve deck having mesh openings to let the oocysts pass, to obtain an aqueous filtrate comprising the oocysts and a first residue comprising particles larger than the oocysts,and sieving the aqueous filtrate over a second sieve deck having mesh openings to obstruct passing of the oocysts through this sieve deck, to obtain a second residue comprising the purified oocysts and a waist filtrate comprising particles smaller than the oocysts. The invention also pertains to a system suitable for applying this method and to oocysts obtained therewith.

    Vaccine Against Rhipicephalus Ticks
    3.
    发明申请
    Vaccine Against Rhipicephalus Ticks 有权
    疫苗针对蜱螨

    公开(公告)号：US20160051649A1

    公开(公告)日：2016-02-25

    申请号：US14780115

    申请日：2014-03-28

    申请人： INTERVET INTERNATIONAL B.V. ,  INTERVET INC.

    发明人： Theodorus Petrus Maria Schetters ,  Theodorus Jansen

    IPC分类号： A61K39/00 ,  A61K9/107

    CPC分类号： A61K39/0003 ,  A61K9/107 ,  A61K2039/54 ,  A61K2039/545 ,  A61K2039/55505 ,  A61K2039/55566 ,  A61K2039/55577 ,  A61K2039/70

    摘要： The present invention generally relates to the fields of parasitology and immunology, and especially to a vaccine against Rhipicephalus ticks. In particular the invention relates to a composition comprising a first and a second protein, in particular Bm86 and Subolesin proteins, including their homologs or immunogenic fragments; to the use of such a composition as a vaccine against Rhipicephalus ticks, and to the use of the first and the second isolated proteins for the vaccination of a target against Rhipicephalus ticks.

    摘要翻译： 本发明一般涉及寄生虫学和免疫学领域，尤其涉及针对蜱螨的疫苗。 特别地，本发明涉及包含第一和第二蛋白质，特别是Bm86和亚金属蛋白质的组合物，包括其同源物或免疫原性片段; 使用这种组合物作为针对胭脂红蜱的疫苗，以及使用第一和第二种分离的蛋白质用于针对蜱螨的接种疫苗。

    Vaccine against Rhipicephalus ticks
    4.
    发明授权
    Vaccine against Rhipicephalus ticks 有权
    疫苗对抗蜱螨

    公开(公告)号：US09579369B2

    公开(公告)日：2017-02-28

    申请号：US14780115

    申请日：2014-03-28

    申请人： INTERVET INTERNATIONAL B.V. ,  INTERVET INC.

    发明人： Theodorus Petrus Maria Schetters ,  Theodorus Jansen

    IPC分类号： A61K39/00 ,  A61K39/002 ,  A61K49/00 ,  A61K9/107

    CPC分类号： A61K39/0003 ,  A61K9/107 ,  A61K2039/54 ,  A61K2039/545 ,  A61K2039/55505 ,  A61K2039/55566 ,  A61K2039/55577 ,  A61K2039/70

    摘要： The present invention generally relates to the fields of parasitology and immunology, and especially to a vaccine against Rhipicephalus ticks. In particular the invention relates to a composition comprising a first and a second protein, in particular Bm86 and Subolesin proteins, including their homologs or immunogenic fragments; to the use of such a composition as a vaccine against Rhipicephalus ticks, and to the use of the first and the second isolated proteins for the vaccination of a target against Rhipicephalus ticks.

    摘要翻译： 本发明一般涉及寄生虫学和免疫学领域，尤其涉及针对蜱螨的疫苗。 特别地，本发明涉及包含第一和第二蛋白质，特别是Bm86和亚金属蛋白质的组合物，包括其同源物或免疫原性片段; 使用这种组合物作为针对胭脂红蜱的疫苗，以及使用第一和第二种分离的蛋白质用于针对蜱螨的接种疫苗。

    Method to purify coccidial oocysts from animal faeces, a system suitable for applying this method and oocysts obtained therewith
    6.
    发明授权
    Method to purify coccidial oocysts from animal faeces, a system suitable for applying this method and oocysts obtained therewith 有权

    公开(公告)号：US10689612B2

    公开(公告)日：2020-06-23

    申请号：US15300499

    申请日：2015-04-02

    申请人： Intervet inc.

    发明人： Koen Gevers ,  Theodorus Petrus Maria Schetters

    IPC分类号： C12N1/10 ,  C12N1/02 ,  B07B1/18 ,  B07B1/22 ,  B07B1/10

    摘要： The invention pertains to a method to purify coccidial oocysts having dimensions between Dmin and Dmax from faeces comprising the steps of collecting the faeces containing the coccidial oocysts from host animals, diluting the faeces in an aqueous medium, separating a coarse fraction comprising macroscopic particulate matter from the diluted faeces and collecting an aqueous fraction containing the oocysts, characterised in that the method further comprises sieving the aqueous fraction over a first sieve deck having mesh openings to let the oocysts pass, to obtain an aqueous filtrate comprising the oocysts and a first residue comprising particles larger than the oocysts, and sieving the aqueous filtrate over a second sieve deck having mesh openings to obstruct passing of the oocysts through this sieve deck, to obtain a second residue comprising the purified oocysts and a waist filtrate comprising particles smaller than the oocysts. The invention also pertains to a system suitable for applying this method and to oocysts obtained therewith.