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    BUBBLE JETTING MEMBER AND METHOD FOR PRODUCING SAME, GAS/LIQUID JETTING MEMBER AND METHOD FOR PRODUCING SAME, LOCALIZED ABLATION DEVICE AND LOCALIZED ABLATION METHOD, INJECTION DEVICE AND INJECTION METHOD, PLASMA-BUBBLE JETTING MEMBER, AND THERAPEUTIC DEVICE AND THERAPEUTIC METHOD
    1.
    发明申请
    BUBBLE JETTING MEMBER AND METHOD FOR PRODUCING SAME, GAS/LIQUID JETTING MEMBER AND METHOD FOR PRODUCING SAME, LOCALIZED ABLATION DEVICE AND LOCALIZED ABLATION METHOD, INJECTION DEVICE AND INJECTION METHOD, PLASMA-BUBBLE JETTING MEMBER, AND THERAPEUTIC DEVICE AND THERAPEUTIC METHOD 审中-公开

    公开(公告)号：US20200337757A1

    公开(公告)日：2020-10-29

    申请号：US16884365

    申请日：2020-05-27

    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

    Inventor： Yoko YAMANISHI ,  Shinya SAKUMA ,  Hiroki KURIKI ,  Fumihito ARAI

    IPC: A61B18/04 ,  C12N15/87 ,  A61M5/30 ,  C12M1/42 ,  A61B18/12 ,  A61N1/44

    Abstract: Provided are a device whereby, during process of a process target such as a cell or the like, localized process of a process part is possible without inflicting damage due to heat, and rejoining and regeneration may proceed readily subsequent to process, and whereby an injection substance may be introduced efficiently; and a device for generating bubbles containing a plasma.Through the use of a localized ablation device employing a bubble jetting member having a core formed from a conductive material, a shell part formed from an insulating material, covering the core and including a section extending from the tip of the core, and a space formed between the extended section of the shell part and the tip of the core, a process target can be treated in localized fashion and without inflicting damage. By further providing an outside shell part at the outer periphery of the shell part, bubbles onto which a solution containing an injection substance has been adsorbed can be ejected, and the injection substance can be introduced during localized ablation of the process target. Additionally, by including a pair of electrodes formed from a conducting material, for generating a plasma in an inert gas, a liquid flow passage through which a liquid flows, and a microscopic flow passage for flow of an inert gas, an inert gas containing a plasma, and bubbles of inert gas containing a plasma, the liquid flow passage and the microscopic flow passage connecting at the downstream side from a section in which plasma is generated in the microscopic flow passage, bubbles containing a plasma can be generated, and can maintain a plasma state even in liquid, whereby therapy of biological tissue can be effected with the plasma.

    FOAM-JETTING MEMBER FOR PROTEIN CRYSTAL DEVICE AND PROTEIN CRYSTAL-ADSORBING FOAM-JETTING MEMBER, PROTEIN CRYSTAL DEVICE AND METHOD FOR CRYSTALLIZING PROTEIN, AND PROTEIN CRYSTAL CUTTING DEVICE AND METHOD FOR CUTTING PROTEIN CRYSTAL
    2.
    发明申请
    FOAM-JETTING MEMBER FOR PROTEIN CRYSTAL DEVICE AND PROTEIN CRYSTAL-ADSORBING FOAM-JETTING MEMBER, PROTEIN CRYSTAL DEVICE AND METHOD FOR CRYSTALLIZING PROTEIN, AND PROTEIN CRYSTAL CUTTING DEVICE AND METHOD FOR CUTTING PROTEIN CRYSTAL 审中-公开
    用于蛋白质晶体装置和蛋白质晶体吸收泡沫浇注构件的泡沫浇注构件，蛋白质晶体装置和用于结晶蛋白质的方法和蛋白质晶体切割装置以及用于切割蛋白质晶体的方法

    公开(公告)号：US20160208405A1

    公开(公告)日：2016-07-21

    申请号：US14914755

    申请日：2014-08-27

    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

    Inventor： Yoko YAMANISHI ,  Fumihito ARAI ,  Hiroki KURIKI

    IPC: C30B7/12 ,  C07K1/30 ,  C30B33/04 ,  C12N9/06 ,  C30B29/58 ,  C30B30/02 ,  C07K14/80 ,  C12N9/36

    CPC classification number: C30B7/12 ,  C07K1/306 ,  C07K14/80 ,  C12N9/0016 ,  C12N9/2462 ,  C12Y104/01014 ,  C30B29/58 ,  C30B30/02 ,  C30B33/04

    Abstract: Provided are a protein crystal device and method for crystallizing protein capable of generating protein crystal without imparting a heat effect, a protein crystal-cutting device and method for cutting protein crystal capable of cutting protein crystal without imparting a heat effect on protein crystal, and bubble-jetting member and protein-adsorbing-bubble-jetting member used in said device. A bubble-jetting member is used in a protein crystal device to jet bubbles into a protein solution to thereby allow protein crystals to be obtained, the bubble-jetting member comprising: a core formed of a conductive material; a shell part formed of an insulating material, including an extended section extending from the tip of the core, and in which at least a portion closely adheres to the core to cover the core; and a gap having a bubble-jetting port, the gap being formed between the extended section and the tip of the core.

    Abstract translation: 本发明提供一种蛋白质晶体装置和结晶蛋白质的方法，该蛋白质能够产生不产生热效应的蛋白质晶体，蛋白质晶体切割装置和切割能够切割蛋白质晶体的蛋白质晶体而不会对蛋白质晶体产生热效应的蛋白质晶体和方法 - 喷射构件和蛋白质吸附 - 气泡喷射构件。 在蛋白质晶体装置中使用气泡喷射构件将气泡喷射到蛋白质溶液中，从而获得蛋白质晶体，气泡喷射构件包括：由导电材料形成的芯; 由绝缘材料形成的壳体部分，包括从所述芯的尖端延伸的延伸部分，并且其中至少一部分紧密地附着到所述芯部以覆盖所述芯部; 以及具有气泡喷射口的间隙，所述间隙形成在所述延伸部和所述芯的尖端之间。

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