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公开(公告)号：US20110118489A1
公开(公告)日：2011-05-19
申请号：US12993713
申请日：2009-05-22
申请人： Jacob J. Schmidt , Tae-Joon Jeon , Jason L. Poulos
发明人： Jacob J. Schmidt , Tae-Joon Jeon , Jason L. Poulos
IPC分类号： C07F9/10
CPC分类号： C07F9/10 , B01L3/5027 , G01N33/48707 , G01N33/5432
摘要： Disclosed are biomimetic membrane precursors and membranes formed therefrom. Also disclosed are methods of making biomimetic membrane precursors and membranes formed therefrom. Methods of using, including methods of storing and handling biomimetic membrane precursors and membranes formed therefrom, are also disclosed
摘要翻译： 公开了仿生膜前体和由其形成的膜。 还公开了制备仿生膜前体和由其形成的膜的方法。 还公开了使用方法，包括存储和处理仿生膜前体和由其形成的膜的方法
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公开(公告)号：US08772041B2
公开(公告)日：2014-07-08
申请号：US12993713
申请日：2009-05-22
申请人： Jacob J. Schmidt , Tae-Joon Jeon , Jason L. Poulos
发明人： Jacob J. Schmidt , Tae-Joon Jeon , Jason L. Poulos
IPC分类号： G01N33/92
CPC分类号： C07F9/10 , B01L3/5027 , G01N33/48707 , G01N33/5432
摘要： Disclosed are biomimetic membrane precursors and membranes formed therefrom. Also disclosed are methods of making biomimetic membrane precursors and membranes formed therefrom. Methods of using, including methods of storing and handling biomimetic membrane precursors and membranes formed therefrom, are also disclosed.
摘要翻译： 公开了仿生膜前体和由其形成的膜。 还公开了制备仿生膜前体和由其形成的膜的方法。 还公开了使用方法，包括存储和处理仿生膜前体和由其形成的膜的方法。
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3.发明申请公开(公告)号：US20130056358A1
公开(公告)日：2013-03-07
申请号：US13520339
申请日：2011-01-05
申请人： Jason L. Poulos , Jacob J. Schmidt
发明人： Jason L. Poulos , Jacob J. Schmidt
CPC分类号： C40B50/08 , C40B40/14 , G01N33/48728
摘要： The invention relates to methods and devices for forming and measuring lipid bilayers, for example, by joining lipid monolayers that self-assemble at the interface of aqueous and organic phases using sessile aqueous droplets in contact with a measurement electrode. At least one of the aqueous solution, the lower aqueous phase, and/or the upper organic phase comprise lipids. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
摘要翻译： 本发明涉及用于形成和测量脂质双层的方法和装置，例如通过连接使用与测量电极接触的无固定水性液滴在水相和有机相的界面处自组装的脂质单层。 水溶液，下部水相和/或上部有机相中的至少一种包含脂质。 该摘要旨在作为用于在特定技术中进行搜索的扫描工具，而不意在限制本发明。
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4.发明授权Masking apertures enabling automation and solution exchange in sessile bilayers 有权遮蔽孔可实现无菌双层的自动化和解决方案交换公开(公告)号：US09150598B2
公开(公告)日：2015-10-06
申请号：US13646305
申请日：2012-10-05
IPC分类号： G01R19/00 , C07F9/22 , G01N27/00 , A61K9/127 , G01N33/487
CPC分类号： C07F9/22 , A61K9/127 , G01N27/00 , G01N33/48728
摘要： Disclosed herein are devices and methods related to the production and measurements of amphiphilic molecule bilayers, which are useful in high throughput electrophysiological screening and ion channel measurement in bilayers. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
摘要翻译： 本文公开了与两亲分子双层的生产和测量相关的装置和方法，其可用于双通道中的高通量电生理筛选和离子通道测量。 该摘要旨在作为用于在特定技术中进行搜索的扫描工具，而不意在限制本发明。
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5.发明申请MASKING APERTURES ENABLING AUTOMATION AND SOLUTION EXCHANGE IN SESSILE BILAYERS 有权使用自动化和解决方案在封闭双层交换中的屏蔽功能公开(公告)号：US20130147461A1
公开(公告)日：2013-06-13
申请号：US13646305
申请日：2012-10-05
CPC分类号： C07F9/22 , A61K9/127 , G01N27/00 , G01N33/48728
摘要： Disclosed herein are devices and methods related to the production and measurements of amphiphilic molecule bilayers. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
摘要翻译： 本文公开了与两亲分子双层的生产和测量相关的装置和方法。 该摘要旨在作为用于在特定技术中进行搜索的扫描工具，而不意在限制本发明。
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公开(公告)号：US09068280B2
公开(公告)日：2015-06-30
申请号：US13520339
申请日：2011-01-05
申请人： Jason L. Poulos , Jacob J. Schmidt
发明人： Jason L. Poulos , Jacob J. Schmidt
IPC分类号： G01N3/02 , C40B50/08 , C40B40/14 , G01N33/487
CPC分类号： C40B50/08 , C40B40/14 , G01N33/48728
摘要： The invention relates to methods and devices for forming and measuring lipid bilayers, for example, by joining lipid monolayers that self-assemble at the interface of aqueous and organic phases using sessile aqueous droplets in contact with a measurement electrode. At least one of the aqueous solution, the lower aqueous phase, and/or the upper organic phase comprise lipids. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
摘要翻译： 本发明涉及用于形成和测量脂质双层的方法和装置，例如通过连接使用与测量电极接触的无固定水性液滴在水相和有机相的界面处自组装的脂质单层。 水溶液，下部水相和/或上部有机相中的至少一种包含脂质。 该摘要旨在作为用于在特定技术中进行搜索的扫描工具，而不意在限制本发明。
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