专利检索 ap:("James Allen Knobelsdorf" OR "Timothy Alan Shepherd" OR "Eric George Tromiczak" OR "Hamideh Zarrinmayeh" OR "Dennis Michael Zimmerman") AND inv:"Eric George Tromiczak" 第 1 页

1.

发明授权
Sulfonamide derivatives 失效
标题翻译：磺酰胺衍生物

公开(公告)号：US06703425B2

公开(公告)日：2004-03-09

申请号：US10276738

申请日：2002-11-15

申请人： James Allen Knobelsdorf , Timothy Alan Shepherd , Eric George Tromiczak , Hamideh Zarrinmayeh , Dennis Michael Zimmerman

发明人： James Allen Knobelsdorf , Timothy Alan Shepherd , Eric George Tromiczak , Hamideh Zarrinmayeh , Dennis Michael Zimmerman

IPC分类号： A61K3118

CPC分类号： C07D213/42 , C07C311/05 , C07C2601/14 , C07D235/14 , C07D333/20

摘要： The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof which is useful for the treatment of conditions associated with glutamate hypofunction, such as psychiatric and neurological disorders

摘要翻译： 本发明涉及可用于治疗与谷氨酸功能减退有关的病症的式（I）化合物或其药学上可接受的盐，例如精神和神经障碍

2.

发明授权
Pyrrole and pyrazole derivatives as potentiators of glutamate receptors 失效
标题翻译：吡咯和吡唑衍生物作为谷氨酸受体的增效剂

公开(公告)号：US07625932B2

公开(公告)日：2009-12-01

申请号：US10570985

申请日：2004-08-27

申请人： Pamela Ann Albaugh , Esteban Dominguez-Manzanares , Jian Eric Hong , William Joseph Hornback , Delu Jiang , Paul Leslie Ornstein , Michelle Lee Thompson , Eric George Tromiczak , Zhipei Wu , Hamideh Zarrinmayeh , Dennis Michael Zimmerman , Ana Maria Castano Mansanet , Larry Gene Huffman , William David Miller

发明人： Pamela Ann Albaugh , Esteban Dominguez-Manzanares , Jian Eric Hong , William Joseph Hornback , Delu Jiang , Paul Leslie Ornstein , Michelle Lee Thompson , Eric George Tromiczak , Zhipei Wu , Hamideh Zarrinmayeh , Dennis Michael Zimmerman , Ana Maria Castano Mansanet , Larry Gene Huffman , William David Miller

IPC分类号： A61K31/675 , A61K31/433 , C07D417/02 , C07D413/02

CPC分类号： C07D207/34 , C07D207/36 , C07D231/14 , C07D401/10 , C07D403/04 , C07D403/10 , C07D403/12 , C07D405/10 , C07D409/10 , C07D409/12 , C07D413/10 , C07D417/10

摘要： The present invention relates to pyrrole and pyrazole compounds of formula (I) and their pharmaceutically acceptable salts, and further relates to their use in treating schizophrenia, cognitive deficits associated with schizophrenia, Alzheimer's disease, dementia of the Alzheimer's type, mild cognitive impairment, or depression. The compounds act as potentiators on glutamate receptors, in particular AMPA and the GluR family.

摘要翻译： 本发明涉及式（I）的吡咯和吡唑化合物及其药学上可接受的盐，并且还涉及它们在治疗精神分裂症，与精神分裂症相关的认知缺陷，阿尔茨海默病，阿尔茨海默氏型痴呆，轻度认知障碍或萧条。这些化合物作为谷氨酸受体，特别是AMPA和GluR家族的增效剂。

3.

发明授权
Thiophene and furan compounds 失效
标题翻译：噻吩和呋喃化合物

公开(公告)号：US07642361B2

公开(公告)日：2010-01-05

申请号：US10596419

申请日：2005-01-05

申请人： Ana Maria Castano Mansanet , Esteban Dominguez-Manzanares , Ana Maria Escribano , Maria Carmen Fernandez , William Joseph Hornback , Alma Maria Jimenez-Aguado , Eric George Tromiczak , Zhipei Wu , Hamideh Zarrinmayeh , Dennis Michael Zimmerman

发明人： Ana Maria Castano Mansanet , Esteban Dominguez-Manzanares , Ana Maria Escribano , Maria Carmen Fernandez , William Joseph Hornback , Alma Maria Jimenez-Aguado , Eric George Tromiczak , Zhipei Wu , Hamideh Zarrinmayeh , Dennis Michael Zimmerman

IPC分类号： C07D333/38

CPC分类号： C07D307/68 , C07D333/38 , C07D409/10 , C07D417/10

摘要： The present invention relates to thiophene and furan compounds and their pharmaceutically acceptable salts, and further relates to their use in treating schizophrenia, cognitive deficits associated with schizophrenia, Alzheimer's disease, dementia of the Alzheimer's type, mild cognitive impairment, or depression.

摘要翻译： 本发明涉及噻吩和呋喃化合物及其药学上可接受的盐，并且还涉及它们在治疗精神分裂症，与精神分裂症相关的认知缺陷，阿尔茨海默病，阿尔茨海默氏型痴呆，轻度认知障碍或抑郁症中的用途。

4.

发明授权
Sulphonamide derivatives 失效
标题翻译：磺酰胺衍生物

公开(公告)号：US06693137B1

公开(公告)日：2004-02-17

申请号：US09744418

申请日：2001-01-23

申请人： Macklin Brian Arnold , David Michael Bender , Buddy Eugene Cantrell , Winton Dennis Jones , Paul Leslie Ornstein , Richard Lee Simon , Edward C. R. Smith , Eric George Tromiczak , Hamideh Zarrinmayeh , Dennis Michael Zimmerman

发明人： Macklin Brian Arnold , David Michael Bender , Buddy Eugene Cantrell , Winton Dennis Jones , Paul Leslie Ornstein , Richard Lee Simon , Edward C. R. Smith , Eric George Tromiczak , Hamideh Zarrinmayeh , Dennis Michael Zimmerman

IPC分类号： A61K3118

CPC分类号： C07D213/64 , C07C311/04 , C07C311/05 , C07C323/12 , C07C323/60 , C07C2601/14 , C07D211/58 , C07D213/65 , C07D239/34 , C07D295/088 , C07D295/15

摘要： The present invention relates to the potentiation of glutamate receptor function using certain sulphonamide derivatives. It also relates to novel sulphonamide derivatives, to processes for their preparation and to pharmaceutical compositions containing them.

摘要翻译： 本发明涉及使用某些磺酰胺衍生物增强谷氨酸受体功能。它还涉及新型磺酰胺衍生物，其制备方法和含有它们的药物组合物。

5.

发明授权
Serotonin and norepinephrine reuptake inhibitor 失效
标题翻译： 5-羟色胺和去甲肾上腺素再摄取抑制剂

公开(公告)号：US08173821B2

公开(公告)日：2012-05-08

申请号：US12754800

申请日：2010-04-06

申请人： Nicolas Jacques Francois Dreyfus , Sandra Ann Filla , Anette Margareta Johansson , Thierry J. Masquelin , Jikesh Arvind Shah , Eric George Tromiczak , Magnus Wilhelm Walter

发明人： Nicolas Jacques Francois Dreyfus , Sandra Ann Filla , Anette Margareta Johansson , Thierry J. Masquelin , Jikesh Arvind Shah , Eric George Tromiczak , Magnus Wilhelm Walter

IPC分类号： C07D213/62 , A61K31/44

CPC分类号： C07D401/12 , A61K31/4439

摘要： A serotonin and norepinephrine reuptake inhibitor of the formula: its uses, and methods for its preparation are described.

摘要翻译： 描述了5-羟色胺和去甲肾上腺素再摄取抑制剂，其用途及其制备方法。