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公开(公告)号:US20080050790A1
公开(公告)日:2008-02-28
申请号:US11778598
申请日:2007-07-16
申请人: James Metz , Craig Weaver , William Barclay , James Flatt
发明人: James Metz , Craig Weaver , William Barclay , James Flatt
CPC分类号: C12N15/52 , A23D7/001 , A23L33/115 , A23L33/135 , C07K14/28 , C12P7/6427 , C12P7/6472
摘要: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
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公开(公告)号:US20080040822A1
公开(公告)日:2008-02-14
申请号:US11778620
申请日:2007-07-16
申请人: James Metz , Craig Weaver , William Barclay , James Flatt
发明人: James Metz , Craig Weaver , William Barclay , James Flatt
CPC分类号: C12N15/52 , A23D7/001 , A23L33/115 , A23L33/135 , C07K14/28 , C12P7/6427 , C12P7/6472
摘要: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
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公开(公告)号:US20080038796A1
公开(公告)日:2008-02-14
申请号:US11778601
申请日:2007-07-16
申请人: James Metz , Craig Weaver , William Barclay , James Flatt
发明人: James Metz , Craig Weaver , William Barclay , James Flatt
CPC分类号: C12N15/52 , A23D7/001 , A23L33/115 , A23L33/135 , C07K14/28 , C12P7/6427 , C12P7/6472
摘要: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
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公开(公告)号:US20080044873A1
公开(公告)日:2008-02-21
申请号:US11778614
申请日:2007-07-16
申请人: James Metz , Craig Weaver , William Barclay , James Flatt
发明人: James Metz , Craig Weaver , William Barclay , James Flatt
CPC分类号: C12N15/52 , A23D7/001 , A23L33/115 , A23L33/135 , C07K14/28 , C12P7/6427 , C12P7/6472
摘要: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
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公开(公告)号:US20080044871A1
公开(公告)日:2008-02-21
申请号:US11778608
申请日:2007-07-16
申请人: James Metz , Craig Weaver , William Barclay , James Flatt
发明人: James Metz , Craig Weaver , William Barclay , James Flatt
CPC分类号: C12N15/52 , A23D7/001 , A23L33/115 , A23L33/135 , C07K14/28 , C12P7/6427 , C12P7/6472
摘要: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
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公开(公告)号:US20080038797A1
公开(公告)日:2008-02-14
申请号:US11778617
申请日:2007-07-16
申请人: James Metz , Craig Weaver , William Barclay , James Flatt
发明人: James Metz , Craig Weaver , William Barclay , James Flatt
CPC分类号: C12N15/52 , A23D7/001 , A23L33/115 , A23L33/135 , C07K14/28 , C12P7/6427 , C12P7/6472
摘要: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
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公开(公告)号:US20080038379A1
公开(公告)日:2008-02-14
申请号:US11778570
申请日:2007-07-16
申请人: James Metz , Craig Weaver , William Barclay , James Flatt
发明人: James Metz , Craig Weaver , William Barclay , James Flatt
CPC分类号: C12N15/52 , A23D7/001 , A23L33/115 , A23L33/135 , C07K14/28 , C12P7/6427 , C12P7/6472
摘要: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
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公开(公告)号:US20080044870A1
公开(公告)日:2008-02-21
申请号:US11778605
申请日:2007-07-16
申请人: James Metz , Craig Weaver , William Barclay , James Flatt
发明人: James Metz , Craig Weaver , William Barclay , James Flatt
CPC分类号: C12N15/52 , A23D7/001 , A23L33/115 , A23L33/135 , C07K14/28 , C12P7/6427 , C12P7/6472
摘要: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
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公开(公告)号:US20080044869A1
公开(公告)日:2008-02-21
申请号:US11778604
申请日:2007-07-16
申请人: James Metz , Craig Weaver , William Barclay , James Flatt
发明人: James Metz , Craig Weaver , William Barclay , James Flatt
CPC分类号: C12N15/52 , A23D7/001 , A23L33/115 , A23L33/135 , C07K14/28 , C12P7/6427 , C12P7/6472
摘要: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
摘要翻译: 本发明一般涉及多不饱和脂肪酸(PUFA)聚酮化合物合酶(PKS)系统,其同源物分离到分离的核酸分子和编码这种PUFA PKS系统的生物活性结构域的重组核酸分子,所述基因修饰的生物体包含PUFA PKS 系统,制备和使用这些系统用于生产感兴趣的生物活性分子的方法,以及用于鉴定具有这种PUFA PKS系统的新的细菌和非细菌微生物的新方法。
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公开(公告)号:US20080044868A1
公开(公告)日:2008-02-21
申请号:US11778575
申请日:2007-07-16
申请人: James Metz , Craig Weaver , William Barclay , James Flatt
发明人: James Metz , Craig Weaver , William Barclay , James Flatt
CPC分类号: C12N15/52 , A23D7/001 , A23L33/115 , A23L33/135 , C07K14/28 , C12P7/6427 , C12P7/6472
摘要: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
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