STABILIZED OPHTHALMIC GALACTOMANNAN FORMULATIONS
    1.
    发明申请
    STABILIZED OPHTHALMIC GALACTOMANNAN FORMULATIONS 审中-公开
    稳定的眼药水制剂

    公开(公告)号:US20110275593A1

    公开(公告)日:2011-11-10

    申请号:US13100439

    申请日:2011-05-04

    IPC分类号: A61K31/736 A61P27/04

    摘要: The present invention relates to viscosity stabilized ophthalmic formulations and ophthalmic formulations suitable for drug delivery. The formulations comprise galactomannans such as guar or hydroxypropyl guar and a borate source such as boric acid. The formulations further comprise a diol alcohol such as sorbitol and, optionally, a pharmaceutically acceptable divalent cation salt such as magnesium chloride.

    摘要翻译: 本发明涉及适用于药物递送的粘度稳定的眼用制剂和眼用制剂。 制剂包含半乳甘露聚糖,例如瓜尔胶或羟丙基瓜尔胶,硼酸盐如硼酸。 制剂还包含二醇醇,例如山梨醇和任选的药学上可接受的二价阳离子盐如氯化镁。

    Polymeric artificial tear system
    5.
    发明授权
    Polymeric artificial tear system 有权
    聚合人工泪液系统

    公开(公告)号:US08685945B2

    公开(公告)日:2014-04-01

    申请号:US13302439

    申请日:2011-11-22

    IPC分类号: A61K31/70

    摘要: The present invention relates to artificial tear formulations and ophthalmic formulations suitable for drug delivery. The formulations comprise galactomannans such as guar or hydroxypropyl guar and a borate source such as boric acid. The formulations further comprise a cis-diol such as sorbitol that interferes with the cross-linking of galactomannan and borate. Optionally, the formulations are substantially free of divalent cations.

    摘要翻译: 本发明涉及适于药物递送的人造泪液制剂和眼用制剂。 制剂包含半乳甘露聚糖,例如瓜尔胶或羟丙基瓜尔胶,硼酸盐如硼酸。 制剂还包含干扰半乳甘露聚糖和硼酸盐的交联的顺式二醇如山梨糖醇。 任选地,制剂基本上不含二价阳离子。

    POLYMERIC ARTIFICIAL TEAR SYSTEM
    7.
    发明申请
    POLYMERIC ARTIFICIAL TEAR SYSTEM 有权
    聚合物人造系统

    公开(公告)号:US20120070402A1

    公开(公告)日:2012-03-22

    申请号:US13302439

    申请日:2011-11-22

    IPC分类号: A61K31/736 A61P27/04

    摘要: The present invention relates to artificial tear formulations and ophthalmic formulations suitable for drug delivery. The formulations comprise galactomannans such as guar or hydroxypropyl guar and a borate source such as boric acid. The formulations further comprise a cis-diol such as sorbitol that interferes with the cross-linking of galactomannan and borate. Optionally, the formulations are substantially free of divalent cations.

    摘要翻译: 本发明涉及适于药物递送的人造泪液制剂和眼用制剂。 制剂包含半乳甘露聚糖,例如瓜尔胶或羟丙基瓜尔胶,硼酸盐如硼酸。 制剂还包含干扰半乳甘露聚糖和硼酸盐的交联的顺式二醇如山梨糖醇。 任选地,制剂基本上不含二价阳离子。

    OPHTHALMIC EMULSION
    8.
    发明申请
    OPHTHALMIC EMULSION 有权
    OPHTHALMIC乳液

    公开(公告)号:US20160338952A1

    公开(公告)日:2016-11-24

    申请号:US15228589

    申请日:2016-08-04

    IPC分类号: A61K9/107 A61K9/00

    摘要: The present invention is directed to an ophthalmic emulsion. The emulsion has a unique combination of ingredients that promotes the stability of small oil droplets within the emulsion. The emulsion also includes a mucoadhesive polymer that aid in delivering a lipid to the ocular surface.

    摘要翻译: 本发明涉及眼用乳液。 该乳液具有促进乳液中小油滴的稳定性的成分的独特组合。 乳剂还包括有助于将脂质递送到眼表面的粘膜粘附聚合物。