公开(公告)号：US5520421A

公开(公告)日：1996-05-28

申请号：US381223

申请日：1995-01-31

申请人： James Warren ,  John Lennon

发明人： James Warren ,  John Lennon

IPC分类号： F16L20060101 ,  F16L19/028 ,  F16L19/04 ,  F16L55/00

CPC分类号： F16L19/0283

摘要： A fluid tight flare nut union is described. Flare nut unions are convenient to install in systems, such as refrigeration systems, and are generally reliably fluid tight. Leaks can occur over time, however, due to environmental stress conditions. Deformable ferrules, in combination with compression nut assemblies, either singly, or redundantly, or in counter rotation redundant assembly, secure the flare nut to the fluid transfer tubing in a locking relationship which prevents the loosening of the flare nut-flare connection with subsequent fluid leakage due to these environmental stresses. Enclosing the complete assembly in water proof insulating material, further insures virtually leak proof operation of the improved flare nut union.

摘要翻译： 描述了流体密封的火炬螺母联合。 扩口螺母工会方便地安装在诸如制冷系统的系统中，并且通常可靠地流体密封。 然而，由于环境压力条件，泄漏可能会发生。 可变形的套圈，与压缩螺母组件结合使用，单独或冗余，或反向旋转冗余组件中，将扩口螺母以锁定关系固定到流体传输管，防止了随后的流体松动螺母 - 由于这些环境压力导致的泄漏。 将完整的组件封闭在防水绝缘材料中，进一步确保改进的扩口螺母联合体的实际泄漏操作。

公开(公告)号：US20190026428A1

公开(公告)日：2019-01-24

申请号：US15872655

申请日：2018-01-16

申请人： James Lu ,  Jim Chou ,  William Lee ,  Chris Williams ,  James Warren ,  Ruomu Jiang

发明人： James Lu ,  Jim Chou ,  William Lee ,  Chris Williams ,  James Warren ,  Ruomu Jiang

IPC分类号： G06F19/22 ,  G06F9/54 ,  G06F17/30 ,  G06F19/24 ,  G06F19/28

摘要： Systems, platforms, methods and media for providing genomic services are disclosed. In one example, a genomic services platform comprises a network interface through which are received genomic sequence reads derived from a biological sample obtained from a user The platform also includes a bioinformatics processing pipeline including a read alignment module configured to generate observed sequence data by aligning the sequence reads relative to a reference sequence, a variant calling module operative to identify observed variants in the observed sequence data, and a variant refinement module for producing a set of refined variants associated with the user. A variant imputation module produces a set of imputed variants associated with the user, and a variant storage module disposed to receive a query from network infrastructure of a partner application provider and to provide selected ones of the refined or imputed variants in response to the query.

公开(公告)号：US07259751B2

公开(公告)日：2007-08-21

申请号：US10771849

申请日：2004-02-03

申请人： Dominic Hughes ,  James Warren ,  Orkut Buyukkokten

发明人： Dominic Hughes ,  James Warren ,  Orkut Buyukkokten

IPC分类号： G09G5/00

CPC分类号： G06F3/0488 ,  G06F3/0233

摘要： A method for evaluating an input system interfacing a human user with an electronic device uses empirically determined bi-action times for users to perform a second input action (e.g., pressing a second key) immediately after performing a first input action (e.g., pressing a first key). The bi-action times (or, more generally, n-action times) are used together with a selected interface map which associates input actions (e.g., pressing keys) to corresponding signifiers (e.g., characters) to calculate a peak expert input rate for the input system. One or more optimized interface maps can be found by combining the evaluation method with any of various optimization strategies. For example, one method for optimizing the input system repeatedly changes the interface map and recalculates the peak expert input rate, while another optimization method calculates peak expert input rates for multiple interface maps in parallel. The evaluation and optimization methods apply to a wide variety of users, input devices, and types of communication and control between them.

摘要翻译： 用于评估与人电子设备接口的输入系统的方法使用经验确定的双动作时间，用户在执行第一输入动作之后立即执行第二输入动作（例如，按压第二键）（例如，按压 第一键）。 双动作时间（或更一般地，n动作时间）与选择的界面图一起使用，其将输入动作（例如，按键）与相应的符号（例如，字符）相关联，以计算峰值专家输入速率 输入系统。 通过将评估方法与各种优化策略中的任一种组合，可以找到一个或多个优化的界面图。 例如，一种用于优化输入系统的方法反复更改界面图并重新计算峰值专家输入速率，而另一种优化方法并行计算多个接口图的峰值专家输入速率。 评估和优化方法适用于各种用户，输入设备以及它们之间的通信和控制类型。

公开(公告)号：US20190206512A1

公开(公告)日：2019-07-04

申请号：US15872756

申请日：2018-01-16

申请人： James Lu ,  Jim Chou ,  William Lee ,  Chris Williams ,  James Warren ,  Ruomu Jiang

发明人： James Lu ,  Jim Chou ,  William Lee ,  Chris Williams ,  James Warren ,  Ruomu Jiang

IPC分类号： G16B30/10 ,  C12Q1/686 ,  G16B50/00 ,  G16B40/00

CPC分类号： G16B30/10 ,  C12Q1/686 ,  G06F7/14 ,  G06F8/31 ,  G06F8/34 ,  G06F9/4881 ,  G06F9/5038 ,  G06F16/13 ,  G06N7/005 ,  G16B20/00 ,  G16B30/00 ,  G16B40/00 ,  G16B50/00

摘要： Systems, platforms, methods and media for providing genomic services axe disclosed. In one example, a system for providing genomic services comprises genomic sequencing equipment configured to generate sequence reads based upon a biological sample obtained from a user, store the sequence reads in a FASTQ storage file, and communicate the FASTQ file electronically to a recipient. The system also includes a genomic services platform which includes a network interface through which the sequence reads are received, and a bioinformatics processing pipeline. The bioinformatics processing pipeline includes a read alignment module configured to generate observed sequence data, and a variant calling module is operative to identify observed variants in the observed sequence data. A variant storage module is disposed to receive a query from network infrastructure of a partner application provider and to provide selected ones of refined variants in response to a query.

公开(公告)号：US20190026429A1

公开(公告)日：2019-01-24

申请号：US15872784

申请日：2018-01-16

申请人： James Lu ,  Jim Chou ,  William Lee ,  Chris Williams ,  James Warren ,  Ruomu Jiang

发明人： James Lu ,  Jim Chou ,  William Lee ,  Chris Williams ,  James Warren ,  Ruomu Jiang

IPC分类号： G06F19/22 ,  G06F19/24 ,  G06F7/14 ,  G06F17/30 ,  G06N7/00

摘要： Systems, platforms, methods and media for providing genomic services are disclosed. In one example, a genomic services platform comprises a network interface through which genomic sequence reads derived from a biological sample obtained from a user are received. The platform also includes a bioinformatics processing pipeline that includes a read alignment module configured to receive a genomics file from genomic sequencing equipment and use data contained therein to generate observed sequence data by aligning the sequence reads relative to a reference sequence. A variant calling module identifies observed variants in the observed sequence data and stores the observed variants in a variant calling file. A variant refinement module produces genotype data including a set of refined variants associated with the user, and a variant imputation module produces a set of imputed variants associated with the user. The variant imputation module can separate the genotype data into high-quality and low-quality genotypes based on a genotype quality.

公开(公告)号：US20100111105A1

公开(公告)日：2010-05-06

申请号：US12261250

申请日：2008-10-30

申请人： Ken Hamilton ,  Steve Einhom ,  James Warren

发明人： Ken Hamilton ,  Steve Einhom ,  James Warren

IPC分类号： H04J3/22

CPC分类号： H04L67/322 ,  G06F9/5044 ,  G06F11/008 ,  H04L67/10 ,  H04L67/1002 ,  H04L67/1008 ,  H04L67/1012 ,  Y02D10/22

摘要： According to one embodiment of the present invention, there is provided a data center comprising: a plurality of data center sections, each section having a different predefined level of reliability; and a plurality of sets of applications, each set of applications being populated on one of the plurality of data center sections.

摘要翻译： 根据本发明的一个实施例，提供了一种数据中心，包括：多个数据中心部分，每个部分具有不同的预定级别的可靠性; 以及多组应用程序，每组应用程序被填充在所述多个数据中心部分中的一个上。

公开(公告)号：US20070017776A1

公开(公告)日：2007-01-25

申请号：US11187776

申请日：2005-07-21

申请人： James Warren

发明人： James Warren

IPC分类号： G07F9/08 ,  G06F19/00 ,  G06F7/00 ,  G06F9/00

CPC分类号： G07F9/08 ,  G07D11/00

摘要： A control system and method for operating a coin redemption machine includes a coin redemption machine functioning as a peripheral device to a separate computer linked to the coin redemption machine through a communications link for reciprocal communication between the coin redemption machine and the computer. The computer controls the activating and deactivating of the coin redemption machine; and the computer and coin redemption machine communicate through commands from the computer, followed by responses from the coin redemption machine.

摘要翻译： 用于操作硬币兑换机的控制系统和方法包括用作通过连接到硬币兑换机的单独计算机的外围设备的硬币兑换机，该通信链路用于硬币兑换机和计算机之间的相互通信。 电脑控制硬币兑换机的启动和停用; 计算机和硬币兑换机通过计算机的命令进行通信，其次是硬币兑换机的响应。

公开(公告)号：US20060109600A1

公开(公告)日：2006-05-25

申请号：US10997602

申请日：2004-11-23

申请人： James Warren

发明人： James Warren

IPC分类号： H02H3/00

CPC分类号： H02H3/07

摘要： Disclosed is a permanent recloser simulator feature for use in a single-pole trip capable recloser control. The permanent recloser simulator feature includes a first logic circuit capable of enabling and disabling operation of the permanent recloser simulator feature in response to receipt of a binary logic signal, and a second logic circuit coupled to the first logic circuit where the second logic circuit is configured to provide an indication of a status of a first pole to a logic engine of the single-pole trip capable recloser control. The permanent recloser simulator feature may further include a third logic circuit associated with a second pole, and a fourth logic circuit associated with a third pole where both are coupled to the first logic circuit. Disabling means of the first logic circuit allow the first, second, third and fourth logic circuit to permanently reside in logic of the recloser control.

摘要翻译： 公开了一种永久重合器模拟器功能，用于单刀跳闸可重新控制的控制。 永久重合器模拟器特征包括能够响应于接收到二进制逻辑信号而启用和禁用永久重合器模拟器特征的操作的第一逻辑电路，以及耦合到第一逻辑电路的第二逻辑电路，其中第二逻辑电路被配置 以提供第一极点的状态的指示到单刀跳闸能力重合器控制的逻辑引擎。 永久重合器模拟器特征还可以包括与第二极相关联的第三逻辑电路，以及与第三极相关联的第四逻辑电路，其中两个耦合到第一逻辑电路。 第一逻辑电路的禁用装置允许第一，第二，第三和第四逻辑电路永久地驻留在重合器控制的逻辑中。

公开(公告)号：US20190026641A1

公开(公告)日：2019-01-24

申请号：US15872731

申请日：2018-01-16

申请人： James Lu ,  Jim Chou ,  William Lee ,  Chris Williams ,  James Warren ,  Ruomu Jiang

发明人： James Lu ,  Jim Chou ,  William Lee ,  Chris Williams ,  James Warren ,  Ruomu Jiang

IPC分类号： G06N7/00 ,  G06F19/22 ,  G06F17/18 ,  G06N99/00

摘要： Systems, platforms, methods and media for providing genomic services are disclosed. In one example, a genomic services platform comprises a network interface through which are received genomic sequence reads derived from a biological sample obtained from a user. The platform also includes a bioinformatics processing pipeline including a read alignment module configured to generate observed sequence data by aligning the sequence reads relative to a reference sequence, a variant calling module operative to identify observed variants in the observed sequence data, and a variant refinement module for producing genotype data including a set of refined variants associated with the user. A variant imputation module produces a set of imputed variants associated with the user, and is configured to receive, as input, at least some of the genotype data and separate the genotype data into high-quality and low-quality genotypes based on a genotype quality.

公开(公告)号：US20190026156A1

公开(公告)日：2019-01-24

申请号：US15872793

申请日：2018-01-16

申请人： James Lu ,  Jim Chou ,  William Lee ,  Chris Williams ,  James Warren ,  Ruomu Jiang

发明人： James Lu ,  Jim Chou ,  William Lee ,  Chris Williams ,  James Warren ,  Ruomu Jiang

IPC分类号： G06F9/50 ,  G06F19/28 ,  G06F19/18 ,  G06F8/30 ,  G06F8/34 ,  G06F9/48

摘要： Systems, platforms, methods and media for providing genomic services are disclosed. In one example, a genomic services platform comprises a network interface through which genomic sequence reads derived from a biological sample are received. The platform also includes a bioinformatics processing pipeline that comprises a read alignment module configured to generate observed sequence data by aligning the sequence reads relative to a reference sequence, a variant calling module operative to identify observed variants in the observed sequence data, and a variant refinement module for producing a set of refined variants associated with the biological sample. A variant imputation module produces a set of imputed variants associated with the user and a variant storage module, operating on a server-less framework, is disposed to receive a query from network infrastructure of a partner application provider and to provide selected ones of the refined or imputed variants m response to the query.