公开(公告)号：US08172895B2

公开(公告)日：2012-05-08

申请号：US11507247

申请日：2006-08-18

申请人： John Lennon Anderson ,  David Ernest Hartley ,  Michael Lawrence-Brown

发明人： John Lennon Anderson ,  David Ernest Hartley ,  Michael Lawrence-Brown

IPC分类号： A61F2/82

CPC分类号： A61F2/07 ,  A61F2/89 ,  A61F2002/061 ,  A61F2002/065 ,  A61F2002/075 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2250/0039

摘要： A method of sizing of a stent graft (20) including placement of fenestrations (30, 32) to ensure access to side branch vessels (13, 15) through the fenestrations when the stent graft is introduced into a body vessel and an assembly method for a stent graft including temporary diameter reduction arrangements to enable partial release of a stent graft to assist with positioning of fenestrations with respect to side branch vessels. The method includes spacing the fenestrations to be the same circumferential distance as the side branch vessels irrespective of the diameter of the stent graft.

摘要翻译： 一种支架移植物（20）的尺寸选择方法，包括放置开窗（30,32）以确保当将支架移植物引入体内容器时通过开窗通入侧分支血管（13,15），以及组装方法 支架移植物，其包括临时直径减小装置，以使部分释放支架移植物有助于相对于侧分支血管定位开窗。 该方法包括将开窗间隔成与侧分支血管相同的圆周距离，而与支架移植物的直径无关。

公开(公告)号：US20110086391A1

公开(公告)日：2011-04-14

申请号：US12995924

申请日：2009-06-01

申请人： Bhupendra Vallabh Kara ,  Christopher David John Lennon

发明人： Bhupendra Vallabh Kara ,  Christopher David John Lennon

IPC分类号： C12P21/00 ,  C12N15/63 ,  C12N1/21 ,  C07H21/04 ,  C07K14/00

CPC分类号： C12N15/70 ,  C12N15/625

摘要： An expression vector for expressing a target polypeptide in a prokaryotic cell is provided. The vector comprises a promoter operably linked to a polynucleotide encoding the target polypeptide operably linked to a eukaryotic secretion leader sequence, the eukaryotic secretion leader sequence encoding a signal peptide sequence selected from the group consisting of: a) MLKRSSWLATLGLLTVASVSTIVYA; b) MKKATFITCLLAVLLVSNPIWNA; c) MKVSAAALAVILIATALCAPASA; d) MKVSTAFLCLLLTVSAFSAQVLA; and e) MKCLLLALGLALACAAQA. Processes for expressing polypeptides and prokaryotic microorganisms comprising such vectors are also provided.

摘要翻译： 提供了用于在原核细胞中表达靶多肽的表达载体。 载体包含可操作地连接到编码与多核苷酸序列有效连接的多核苷酸的启动子，所述多核苷酸可操作地连接到真核分泌前导序列，所述真核细胞分泌前导序列编码选自以下的信号肽序列：a）MLKRSSWLATLGLLTVASVSTIVYA; b）MKKATFITCLLAVLLVSNPIWNA; c）MKVSAAALAVILIATALCAPASA; d）MKVSTAFLCLLLTVSAFSAQVLA; 和e）MKCLLLALGLALACAAQA。 还提供了表达多肽和包含这种载体的原核微生物的方法。

公开(公告)号：US07413573B2

公开(公告)日：2008-08-19

申请号：US10962765

申请日：2004-10-12

申请人： David Ernest Hartley ,  John Lennon Anderson ,  Michael Lawrence-Brown

发明人： David Ernest Hartley ,  John Lennon Anderson ,  Michael Lawrence-Brown

IPC分类号： A61F2/06

CPC分类号： A61F2/856 ,  A61F2/07 ,  A61F2/89 ,  A61F2002/061 ,  A61F2002/067 ,  A61F2002/075 ,  A61F2002/821 ,  A61F2002/828 ,  A61F2220/0075 ,  A61F2230/0069 ,  A61F2230/0078 ,  A61F2250/001 ,  A61F2250/0039

摘要： A stent graft (1) including a tubular wall (3) with at least one fenestration (40) including a peripheral (37) reinforcement around at least part of the fenestration. There can also be a tubular extension (15). The side arm includes a stent (19) and a cover (17) and extends from and is in fluid communication with the fenestration and the stent graft. The stent may be a self expanding stent. The ring and/or tubular extension provides better support and sealing for an extension arm. The fenestration (40) can be circular or if towards the ends of the stent graft may be in the form of a U-shape (50) with an open end.

摘要翻译： 一种包括具有至少一个开窗（40）的管状壁（3）的支架移植物（1），其包括围绕所述开窗的至少一部分的周边（37）加强件。 还可以有管状延伸部（15）。 侧臂包括支架（19）和盖（17），并从开窗和支架移植物延伸并与开窗和支架移植物流体连通。 支架可以是自扩张支架。 环和/或管状延伸部为延伸臂提供更好的支撑和密封。 开窗（40）可以是圆形的，或者如果朝向支架移植物的端部可以是具有开口端的U形（50）的形式。

公开(公告)号：US06428160B2

公开(公告)日：2002-08-06

申请号：US09726100

申请日：2000-11-29

申请人： Joy Roy ,  Babur Hadimioglu ,  Richard N. Ellson ,  Robert Sprague ,  James B. Kruger ,  John Lennon

发明人： Joy Roy ,  Babur Hadimioglu ,  Richard N. Ellson ,  Robert Sprague ,  James B. Kruger ,  John Lennon

IPC分类号： B41J201

CPC分类号： B41J11/002

摘要： An apparatus and method for ink-jet printing on a recording medium is provided which includes the steps of jetting aqueous ink drops on paper in the form of an image. The aqueous ink used is a slow-drying (high-surface tension) ink which does not penetrate the paper/paper fibers for a relatively long time. Prior to penetration of the paper/paper fibers, the water in the droplet is quickly evaporated from the ink while still resident on the paper surface. The evaporation process is substantially completed prior to an additional liquid ink being jetted onto the same or adjoining location of the recording medium. The evaporation is rapid enough to prevent the resident ink from substantially migrating/wicking to any adjacent location or into the recording medium. Further the drying energy is transferred to the resident ink spots from the same direction as the printheads ensuring less energy requirement.

摘要翻译： 提供了一种用于在记录介质上进行喷墨印刷的设备和方法，其包括以图像形式将水性墨滴喷射在纸上的步骤。 使用的水性油墨是一种慢干（高表面张力）油墨，其不会在相对长的时间内渗透纸/纸纤维。 在纸/纸纤维渗透之前，液滴中的水从墨水中迅速蒸发，同时仍然驻留在纸张表面上。 在附加的液体墨水喷射到记录介质的相同或相邻位置之前，蒸发过程基本上完成。 蒸发速度足够快以防止驻留的墨水基本上迁移/吸附到任何相邻位置或记录介质中。 此外，干燥能量从与打印头相同的方向转移到驻留的墨点，确保较少的能量需求。

公开(公告)号：US5778527A

公开(公告)日：1998-07-14

申请号：US707100

申请日：1996-09-03

申请人： Michael Barenboim ,  Mark Edward Mino ,  John Lennon Sullivan, Jr. ,  Kenneth Wayne Watts

发明人： Michael Barenboim ,  Mark Edward Mino ,  John Lennon Sullivan, Jr. ,  Kenneth Wayne Watts

IPC分类号： H01R43/16 ,  H05K13/00 ,  H01R43/20 ,  H05K3/30 ,  H05K13/04

CPC分类号： H05K13/003 ,  H01R43/16 ,  Y10T29/49121 ,  Y10T29/49139 ,  Y10T29/49153 ,  Y10T29/49218 ,  Y10T29/49222 ,  Y10T29/5149 ,  Y10T29/515 ,  Y10T29/53183

摘要： A method is provided for processing a number of "L"-shaped sections within a flat strip to form terminals extending from a component. In the strip, these sections are attached to a web by connecting portions. A number of such sections are simultaneously processed within various stations through which the strip is incrementally fed. These connecting portions are first twisted, so that each "L"-shaped section in the number of such sections extends in a plane perpendicular to the web. Next, these connecting portions are deflected so that outward extending legs of the sections extend in a direction needed for insertion into an electronic component structure. Then, these connecting portions are sheared, as each "L"-shaped section separated from the strip is placed in a slot within a receptacle block. Then, the receptacle block is slid to insert the "L"-shaped sections.

摘要翻译： 提供了一种用于处理扁平条中的多个“L”形部分以形成从部件延伸的端子的方法。 在条带中，这些部分通过连接部分连接到卷材上。 多个这样的部分在不同的工位中被同时处理，通过该工位条带被递增地供给。 这些连接部分首先被扭曲，使得这些部分的数量中的每个“L”形部分在垂直于卷材的平面中延伸。 接下来，这些连接部分被偏转，使得这些部分的向外延伸的支腿沿插入电子部件结构所需的方向延伸。 然后，将这些连接部分剪切，因为与条带分离的每个“L”形部分被放置在插座块内的槽中。 然后，将插座块滑动以插入“L”形部分。

公开(公告)号：US06993655B1

公开(公告)日：2006-01-31

申请号：US09467509

申请日：1999-12-20

申请人： David L. Hecht ,  John Lennon ,  Ralph Merkle

发明人： David L. Hecht ,  John Lennon ,  Ralph Merkle

IPC分类号： H04L9/00 ,  G06K7/10 ,  G06K19/06 ,  G06K9/00

CPC分类号： G06K7/143 ,  G06K19/06009 ,  G06K19/14

摘要： A record and related method is provided for storing encoded information comprising a storage media, first marks on the storage media having a covert code characteristic, with the first marks conveying a covertly marked code and second marks preferably having an overt code characteristic which convey a second overtly marked code useful in decoding the covertly marked code.

摘要翻译： 提供了一种记录和相关方法，用于存储包括存储介质的编码信息，具有隐蔽代码特性的存储介质上的第一标记，其中第一标记传送隐蔽标记的代码，并且优选地具有传达第二代码的公开代码特性的第二标记 明显标记的代码对解码隐蔽标记代码有用。

公开(公告)号：US6019558A

公开(公告)日：2000-02-01

申请号：US893360

申请日：1997-07-16

申请人： James J. Warren ,  John Lennon

发明人： James J. Warren ,  John Lennon

IPC分类号： F16L19/00 ,  F25B41/00 ,  F16B39/10 ,  F16B39/284 ,  F16J15/00

CPC分类号： F16L19/005 ,  F25B41/003

摘要： A nut and bolt securing device is disclosed to prevent loosening of the assembly due to environmental conditions. In a first version of the invention the two piece device is fitted over a nut and a portion of a bolt extending from the nut, the two sections of the device being secured together with set screws, with serrations within the device, and one or more set screws engaging the front end of the device. In a second version of the device a shelf like planar projection on the front end of the device engages a planar surface on a nut, again combining with the serrations within the device to prevent fastener loosening. The device is particularly described in use in conjunction with refrigerant system flare nuts so as to prevent loss of refrigerant at these flare nut unions.

摘要翻译： 公开了螺母和螺栓固定装置以防止由于环境条件而使组件松动。 在本发明的第一版本中，两件式装置安装在螺母和从螺母延伸的螺栓的一部分上，装置的两个部分用固定螺钉固定在装置内，并且一个或多个 固定螺钉接合设备的前端。 在设备的第二版本中，设备前端上的类似平面突起的搁板与螺母上的平坦表面接合，再次与装置内的锯齿结合以防止紧固件松动。 该装置特别地描述为与制冷剂系统火炬螺母结合使用，以防止在这些火炬螺母接头处的制冷剂损失。

公开(公告)号：US5520421A

公开(公告)日：1996-05-28

申请号：US381223

申请日：1995-01-31

申请人： James Warren ,  John Lennon

发明人： James Warren ,  John Lennon

IPC分类号： F16L20060101 ,  F16L19/028 ,  F16L19/04 ,  F16L55/00

CPC分类号： F16L19/0283

摘要： A fluid tight flare nut union is described. Flare nut unions are convenient to install in systems, such as refrigeration systems, and are generally reliably fluid tight. Leaks can occur over time, however, due to environmental stress conditions. Deformable ferrules, in combination with compression nut assemblies, either singly, or redundantly, or in counter rotation redundant assembly, secure the flare nut to the fluid transfer tubing in a locking relationship which prevents the loosening of the flare nut-flare connection with subsequent fluid leakage due to these environmental stresses. Enclosing the complete assembly in water proof insulating material, further insures virtually leak proof operation of the improved flare nut union.

摘要翻译： 描述了流体密封的火炬螺母联合。 扩口螺母工会方便地安装在诸如制冷系统的系统中，并且通常可靠地流体密封。 然而，由于环境压力条件，泄漏可能会发生。 可变形的套圈，与压缩螺母组件结合使用，单独或冗余，或反向旋转冗余组件中，将扩口螺母以锁定关系固定到流体传输管，防止了随后的流体松动螺母 - 由于这些环境压力导致的泄漏。 将完整的组件封闭在防水绝缘材料中，进一步确保改进的扩口螺母联合体的实际泄漏操作。

公开(公告)号：US08012193B2

公开(公告)日：2011-09-06

申请号：US10962763

申请日：2004-10-12

申请人： David Ernest Hartley ,  John Lennon Anderson ,  Roy K. Greenberg ,  Wolf Stelter

发明人： David Ernest Hartley ,  John Lennon Anderson ,  Roy K. Greenberg ,  Wolf Stelter

IPC分类号： A61F2/06

CPC分类号： A61F2/954 ,  A61F2/07 ,  A61F2/82 ,  A61F2/90 ,  A61F2/958 ,  A61F2/962 ,  A61F2/966 ,  A61F2002/067 ,  A61F2002/9511 ,  A61F2002/9583 ,  A61F2002/9665

摘要： An introduction arrangement for a fenestrated or branched stent graft (13) intended for deployment into the lumen of a vessel having a blind vessel extending from it. The introducer (1) has a distal end intended to remain outside a patient in use and a proximal end with a nose cone dilator (11) and an arrangement to retain the branched stent graft distally of the nose cone dilator. A sheath (15) on the introducer extends over the branched stent graft to the nose cone dilator. An indwelling catheter (22) extends from the distal end of the introducer and enters the fenestration or side arm and through to the nose cone dilator, the indwelling catheter has a guide wire (29) extending through it. The guide wire can be extended beyond the nose cone dilator in use before the sheath is withdrawn from the branched stent graft so that it can be snared from the contra-lateral artery.

摘要翻译： 用于开窗或分枝的支架移植物（13）的引入装置，其用于展开到具有从其延伸的盲血管的血管的内腔中。 导引器（1）具有旨在在使用中保持在患者外部的远端和具有鼻锥形扩张器（11）的近端和用于将分支的支架移植物保持在鼻锥扩张器的远侧的布置。 引导器上的护套（15）在分支支架移植物上延伸到鼻锥扩张器。 留置导管（22）从引导器的远端延伸并进入开窗或侧臂并通过鼻锥扩张器，留置导管具有延伸通过其的导丝（29）。 引导线可以延伸到使用中的鼻锥扩张器之外，然后将护套从分支的支架移植物中取出，使得其可以从对侧动脉中截获。

公开(公告)号：US06734424B2

公开(公告)日：2004-05-11

申请号：US10146134

申请日：2002-05-16

申请人： John Lennon ,  Taraneh Norouzi

发明人： John Lennon ,  Taraneh Norouzi

IPC分类号： B01D5944

CPC分类号： G01N35/1016 ,  B01L3/0262 ,  B01L2400/022 ,  B01L2400/0487 ,  G01N35/1004 ,  G01N2035/102 ,  H01J49/00

摘要： An automated pipetting apparatus and method for forming sample spots on a support include a pipette. A robotic assembly moves a sample container, such as a multiwell microtiter plate, and the support to the pipette for receiving and dispensing liquid samples. The pipette draws a predetermined volume of the liquid sample from the sample container into the axial passage of the pipette and forms a pocket of a gaseous material above and forms a barrier material below the volume of the liquid sample. The liquid sample is drawn into the pipette a distance sufficient to form a space between the liquid sample and the outlet of the pipette and to contain the liquid sample completely within the pipette. The volume of the barrier material, which is typically air or other fluid, separates the liquid sample a suitable distance from the outlet end of the pipette to prevent the liquid sample from flowing outward under gravity and being drawn along the outer surfaces of the pipette by the surface tension of the liquid, thereby preventing or inhibiting evaporation and preventing deposits from forming on the outer surface of the pipette. The pipette dispenses the liquid sample with sufficient force so that substantially the entire volume of the liquid sample is dispensed from the pipette directly onto the support. The support can be, for example, a sample plate of a MALDI mass spectrometer. The pipette deposits the liquid samples to form sample spots on the sample plate for analysis by the mass spectrometer.

摘要翻译： 用于在支撑体上形成样品斑点的自动移液装置和方法包括移液管。 机器人组件将诸如多孔微量滴定板的样品容器移动到移液管上以接收和分配液体样品。 移液管将样品容器中的预定体积的液体样品从吸液管的轴向通道吸入，并在上面形成气态物质的口袋，并在液体样品的体积之下形成阻隔材料。 将液体样品吸入移液管中足以在液体样品和移液管出口之间形成空间并将液体样品完全包含在移液管内的距离。 通常为空气或其他流体的阻隔材料的体积将液体样品与吸液管的出口端隔开合适的距离，以防止液体样品在重力作用下向外流动并沿着吸液管的外表面被拉伸 液体的表面张力，从而防止或抑制蒸发并防止沉积物在移液管的外表面上形成。 移液管以足够的力分配液体样品，使得液体样品的基本上整个体积从移液管直接分配到载体上。 载体可以是例如MALDI质谱仪的样品板。 移液管沉积液体样品，在样品板上形成样品点，用于质谱仪分析。