公开(公告)号：US12295997B2

公开(公告)日：2025-05-13

申请号：US17366946

申请日：2021-07-02

Applicant: Janssen Biotech, Inc.

Inventor： Jason Lee DeHart ,  Vipul Bhargava ,  Manuel Alejandro Sepulveda

IPC: A61K39/00 ,  A61K9/51 ,  A61K45/06 ,  A61P35/00 ,  C07K14/005 ,  C07K14/47 ,  C12N7/00 ,  C12N15/86

Abstract: Disclosed herein are self-replicating RNA molecules encoding prostate neoantigens, vaccines, and methods of treating and preventing prostate cancer.

公开(公告)号：US20230029453A1

公开(公告)日：2023-02-02

申请号：US17366946

申请日：2021-07-02

Applicant: Janssen Biotech, Inc.

Inventor： Jason Lee DeHart ,  Vipul Bhargava ,  Manuel Alejandro Sepulveda

IPC: A61K39/00 ,  C07K14/005 ,  C07K14/47 ,  A61P35/00 ,  A61K45/06 ,  C12N7/00 ,  C12N15/86 ,  A61K9/51

Abstract: Disclosed herein are self-replicating RNA molecules encoding prostate neoantigens, vaccines, and methods of treating and preventing prostate cancer.

公开(公告)号：US20230024133A1

公开(公告)日：2023-01-26

申请号：US17366545

申请日：2021-07-02

Applicant: Janssen Biotech, Inc.

Inventor： Jason Lee DeHart ,  Vipul Bhargava ,  Patrick Wilkinson ,  Manuel Alejandro Sepulveda

IPC: A61K39/12 ,  A61K39/00

Abstract: Disclosed herein are self-replicating RNA molecules encoding prostate neoantigens, vaccines, and method of treating and preventing prostate cancer using the self-replicating RNA molecules and vaccines.