公开(公告)号：US20220411504A1

公开(公告)日：2022-12-29

申请号：US17330462

申请日：2021-05-26

Applicant: Janssen Biotech, Inc.

Inventor： Raymond Brittingham ,  Scott R. Brodeur ,  Rajkumar Ganesan ,  Jaclyn Hoover ,  Steven A. Jacobs ,  Colleen M. Kane ,  Jinquan Luo ,  Sanjaya Singh ,  Fang Yi ,  Adam Zwolak ,  Triveni K. Bhatt ,  Michael Dennis Feldkamp ,  Sherry Lynn La Porte

IPC: C07K16/28 ,  A61P35/00 ,  C07K16/30 ,  C07K16/42

Abstract: The disclosure provides antigen binding domains that bind cluster of differentiation 3 (CD3) protein, comprising the antigen binding domains that bind CD3ε, polynucleotides encoding them, vectors, host cells, methods of making and using them.