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公开(公告)号：US20250145711A1
公开(公告)日：2025-05-08
申请号：US18830184
申请日：2024-09-10
Applicant: Janssen Biotech, Inc.
Inventor： Adam Zwolak , Raymond Brittingham , Scott R. Brodeur , Rajkumar Ganesan , Sherry Lynn La Porte , Jinquan Luo , Fang Yi , Colleen M. Kane , Triveni K. Bhatt
Abstract: The disclosure provides antigen binding domains that bind cluster of differentiation 3 (CD3) protein, comprising the antigen binding domains that bind CD3ε, polynucleotides encoding them, vectors, host cells, methods of making and using them.
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2.发明申请公开(公告)号：US20210040210A1
公开(公告)日：2021-02-11
申请号：US16937285
申请日：2020-07-23
Applicant: Janssen Biotech, Inc.
Inventor： Rajkumar Ganesan , John Lee , Jinquan Luo , Theresa McDevitt , Fei Shen , Degang Song , Raymond Brittingham , Sathyadevi Venkataramani , Sanjaya Singh , Yonghong Zhao , Fang Yi , Sherry Lynn La Porte
Abstract: Embodiments of the present invention provide isolated proteins comprising antigen binding domains that bind kallikrein related peptidase 2 (hK2), including monospecific and bispecific antibodies. Additional embodiments of the invention provide polynucleotides encoding the hk2-specific proteins, vectors, host cells, and methods of making and using them.
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公开(公告)号：US20220411504A1
公开(公告)日：2022-12-29
申请号：US17330462
申请日：2021-05-26
Applicant: Janssen Biotech, Inc.
Inventor： Raymond Brittingham , Scott R. Brodeur , Rajkumar Ganesan , Jaclyn Hoover , Steven A. Jacobs , Colleen M. Kane , Jinquan Luo , Sanjaya Singh , Fang Yi , Adam Zwolak , Triveni K. Bhatt , Michael Dennis Feldkamp , Sherry Lynn La Porte
Abstract: The disclosure provides antigen binding domains that bind cluster of differentiation 3 (CD3) protein, comprising the antigen binding domains that bind CD3ε, polynucleotides encoding them, vectors, host cells, methods of making and using them.
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4.发明授权公开(公告)号：US12077585B2
公开(公告)日：2024-09-03
申请号：US16937285
申请日：2020-07-23
Applicant: Janssen Biotech, Inc.
Inventor： Rajkumar Ganesan , John Lee , Jinquan Luo , Theresa McDevitt , Fei Shen , Degang Song , Raymond Brittingham , Sathyadevi Venkataramani , Sanjaya Singh , Yonghong Zhao , Fang Yi , Sherry Lynn La Porte
CPC classification number: C07K16/2809 , C07K16/34 , C07K2317/14 , C07K2317/31 , C07K2317/565
Abstract: Embodiments of the present invention provide isolated proteins comprising antigen binding domains that bind kallikrein related peptidase 2 (hK2), including monospecific and bispecific antibodies. Additional embodiments of the invention provide polynucleotides encoding the hk2-specific proteins, vectors, host cells, and methods of making and using them.
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公开(公告)号：US11827708B2
公开(公告)日：2023-11-28
申请号：US17388056
申请日：2021-07-29
Applicant: Janssen Biotech, Inc.
Inventor： Natasa Obermajer , Adam Zwolak , Sylvie Laquerre , Dirk Brehmer , Desiree De Lange , Julien Häsler , Shana Versmissen , Theodore D. Petley , Kelly van de Ven , Fang Yi , Sanjaya Singh , Rajkumar Ganesan
CPC classification number: C07K16/2833 , A61P35/00 , C07K16/2809 , A61K2039/505 , A61K2039/545 , C07K2317/31 , C07K2317/55 , C07K2317/622
Abstract: The invention provides antigen binding domains that bind human leukocyte antigen G (HLA-G) protein comprising the antigen binding domains that bind HLA-G, polynucleotides encoding them, vectors, host cells, methods of making and using them.
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Patent Agency Ranking
公开(公告)号：US20220033505A1
公开(公告)日：2022-02-03
申请号：US17388056
申请日：2021-07-29
Applicant: Janssen Biotech, Inc.
Inventor： Natasa Obermajer , Adam Zwolak , Sylvie Laquerre , Dirk Brehmer , Desiree De Lange , Julien Häsler , Shana Versmissen , Theodore D. Petley , Kelly van de Ven , Fang Yi , Sanjaya Singh
Abstract: The invention provides antigen binding domains that bind human leukocyte antigen G (HLA-G) protein comprising the antigen binding domains that bind HLA-G, polynucleotides encoding them, vectors, host cells, methods of making and using them.
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公开(公告)号：US12084501B2
公开(公告)日：2024-09-10
申请号：US17701764
申请日：2022-03-23
Applicant: Janssen Biotech, Inc.
Inventor： Adam Zwolak , Raymond Brittingham , Scott R. Brodeur , Rajkumar Ganesan , Sherry Lynn La Porte , Jinquan Luo , Fang Yi , Colleen M. Kane , Triveni K. Bhatt
CPC classification number: C07K16/2809 , C07K16/468 , C12N15/85 , A61K2039/507 , C07K2317/31 , C07K2317/55 , C07K2317/622
Abstract: The disclosure provides antigen binding domains that bind cluster of differentiation 3 (CD3) protein, comprising the antigen binding domains that bind CD3ε, polynucleotides encoding them, vectors, host cells, methods of making and using them.
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公开(公告)号：US12071466B2
公开(公告)日：2024-08-27
申请号：US16936719
申请日：2020-07-23
Applicant: Janssen Biotech, Inc.
Inventor： Raymond Brittingham , Rajkumar Ganesan , Sherry La Porte , John T. Lee , Jinquan Luo , Theresa McDevitt , Fei Shen , Sanjaya Singh , Degang Song , Sathyadevi Venkataramani , Fang Yi , Yonghong Zhao
IPC: A61K35/17 , A61K38/00 , C07K14/705 , C07K14/725 , C07K16/40
CPC classification number: C07K14/7051 , A61K35/17 , C07K14/70517 , C07K14/70596 , C07K16/40 , A61K38/00 , C07K2317/53 , C07K2317/565 , C07K2317/622 , C07K2319/02 , C07K2319/03
Abstract: The present disclosure provides for chimeric antigen receptors (CARs) that specifically target a human Kallikrein-2 (hK2), and immunoresponsive cells comprising such CARs, for the treatment of cancer.
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9.发明公开公开(公告)号：US20240124583A1
公开(公告)日：2024-04-18
申请号：US18397711
申请日：2023-12-27
Applicant: Janssen Biotech, Inc.
Inventor： Rajkumar Ganesan , John Lee , Jinquan Luo , Theresa McDevitt , Fei Shen , Degang Song , Raymond Brittingham , Sathyadevi Venkataramani , Sanjaya Singh , Yonghong Zhao , Fang Yi , Sherry Lynn LaPorte
CPC classification number: C07K16/2809 , C07K16/34 , C07K2317/14 , C07K2317/31 , C07K2317/565
Abstract: Embodiments of the present invention provide isolated proteins comprising antigen binding domains that bind kallikrein related peptidase 2 (hK2), including monospecific and bispecific antibodies. Additional embodiments of the invention provide polynucleotides encoding the hk2-specific proteins, vectors, host cells, and methods of making and using them.
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公开(公告)号：US20230040715A1
公开(公告)日：2023-02-09
申请号：US17701764
申请日：2022-03-23
Applicant: Janssen Biotech, Inc.
Inventor： Adam Zwolak , Raymond Brittingham , Scott R. Brodeur , Rajkumar Ganesan , Sherry Lynn La Porte , Jinquan Luo , Fang Yi , Colleen M. Kane , Triveni K. Bhatt
Abstract: The disclosure provides antigen binding domains that bind cluster of differentiation 3 (CD3) protein, comprising the antigen binding domains that bind CD3ε, polynucleotides encoding them, vectors, host cells, methods of making and using them.
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